Zovirax cream for external use 5% tube 5g

Dosage form

Cream for external use 5% white or almost white, homogeneous.

Structure

acyclovir 5 g

Excipients: propylene glycol, white soft paraffin, cetostearyl alcohol, liquid paraffin, poloxamer 407, sodium lauryl sulfate, dimethicone, glycerol monostearate, macrogol stearate, purified water.

pharmachologic effect

Antiviral drug for external and local use.

Acyclovir is active against Herpes simplex types 1 and 2, Varicella zoster virus, Epstein-Barr virus and cytomegalovirus.

Thymidine kinase of cells infected with a virus through a series of consecutive reactions actively converts acyclovir to mono-, di- and acyclovir triphosphate.

The latter interacts with viral DNA polymerase and is incorporated into DNA, which is synthesized for new viruses.

Thus, defective" viral DNA is formed, which leads to suppression of replication of new generations of viruses.

Pharmacokinetics

With repeated use of the cream, systemic absorption is minimal.

Side effects

Local reactions: sometimes - short-term redness, itching, peeling, burning or tingling in the areas of application of the drug.

Allergic reactions: rarely - allergic dermatitis (more often associated with a reaction to excipients)

in isolated cases - Quincke's edema

Selling features

Available without a prescription

Special conditions

To achieve the maximum therapeutic effect, it is necessary to use the drug already at the first signs of the disease (burning, itching, tingling, feeling of tension and redness).

With pronounced manifestations of herpes of the lips, it is recommended to consult a doctor.

The cream is not recommended to be applied to the mucous membranes of the mouth and eyes, because

development of local inflammation is possible.

When treating genital herpes, it is advisable to avoid sexual intercourse or use condoms.

the use of acyclovir does not prevent sexual transmission of the virus.

Immunocompromised patients should follow the advice of a physician when treating any infectious disease.

Indications

infections of the skin and mucous membranes caused by the Herpes simplex virus types 1 and 2, incl.

herpes of the lips.

Contraindications

hypersensitivity to acyclovir and other components of the drug.

Drug interactions

No interaction of Zovirax® with other drugs has been identified.

Dosage

The drug is recommended to be applied 5 times / (approximately every 4 hours) in a thin layer on the affected and adjacent areas of the skin and mucous membranes.

The duration of treatment is at least 4 days.

In the absence of healing, treatment can be continued for up to 10 days.

If the symptoms of the disease persist for more than 10 days, you should consult your doctor.

The cream is applied either with a cotton swab or with clean hands to avoid additional infection of the affected areas.

Overdose

There are no data on Zovirax® overdose.

Name ENG

ZOVIRAX

Clinical and pharmacological group

Antiviral drug for external use

ATX code

Aciclovir

Dosage

5% x 5g

Structure

acyclovir 5 g. Excipients: propylene glycol, white soft paraffin, cetostearyl alcohol, liquid paraffin, poloxamer 407, sodium lauryl sulfate, dimethicone, glycerol monostearate, macrogol stearate, purified water.

INN / Active ingredient

Acyclovir

Storage conditions and periods

At a temperature not exceeding 25 degrees (do not freeze).

Expiration date: 3 years - tubes

2 years - vials

Specifications

Category

Wound healing

,

Scarring

,

Regenerating agents

Scope of the medicinal product

Dermatology

Release form

Cream

Manufacturer country

Great Britain

Package quantity, pcs

one

Way of introduction

On the skin

,

On the mucous membrane

Vacation conditions

Without recipe

Brand name

Zovirax

The amount of the dosage form in the primary package

5 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiviral agent

Anatomical and therapeutic characteristics

D06BB03 Acyclovir

Dosage form

Cream for external use

Expiration date in days

730

Package weight, g

ten

Mode of application

:

The drug is recommended to be applied 5 times / day (approximately every 4 hours) in a thin layer on the affected and adjacent areas of the skin and mucous membranes. < br> < br> Duration of treatment - at least 4 days.

In the absence of healing, treatment can be continued for up to 10 days.

If the symptoms of the disease persist for more than 10 days, you should consult a doctor. < br> < br> The cream is applied either with a cotton swab or with clean hands to avoid additional infection of the affected areas.

"