Zinocap cream 0.2%, 25 g

• psoriasis

• atopic dermatitis (eczema, neurodermatitis)

• seborrheic dermatitis

• dry skin

The drug is intended for external use.

Used in adults and children from 1 year old.

The cream is applied in a thin layer to the affected areas 2-3 times a day.

Duration of treatment for:

• psoriasis - 1-1.5 months, repeated courses - when signs of exacerbation appear;

• atopic dermatitis - 3-4 weeks;

• seborrheic dermatitis - 2 weeks;

100 g of cream contain:

active substance - zinc pyrithione (in terms of 100% substance) - 0.2 g (0.2%);

excipients : macrogol cetostearate, cetostearyl alcohol, liquid paraffin (vaseline oil), propylene glycol, dexpanthenol (D-Panthenol), sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dodecahydrate, purified water

Hypersensitivity, children under 1 year of age.

Trade name: TsinocapЃ

International non-proprietary name: Zinc pyrithione

Dosage form: cream for external use

Composition:

100 g of cream contain:

active substance - zinc pyrithione (in terms of 100% substance) - 0.2 g (0.2%);

excipients : macrogol cetostearate, cetostearyl alcohol, liquid paraffin (vaseline oil), propylene glycol, dexpanthenol (D-Panthenol), sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dodecahydrate, purified water.

Description

Cream, white or white with a yellowish tinge, odorless or with a weak specific odor.

Pharmacotherapeutic group: dermatoprotective agent

pharmachologic effect

Zinc pyrithione has anti-inflammatory, antibacterial and antifungal activity. The antibacterial activity of zinc pyrithione is manifested against a number of gram-positive and gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp.). Zinc pyrithione reduces the intracellular level of ATP, promotes depolarization of cell membranes, and promotes depolarization of cell membranes.

Antifungal activity is especially pronounced against fungi of the genus Malassezia (formerly Pityrosporum ovale and Pityrosporum orbiculare), which cause inflammation and excessive flaking in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action has not been studied.

Pharmacokinetics

Systemic absorption is negligible. The drug is found in the blood in trace amounts.

Indications for use

• psoriasis

• atopic dermatitis (eczema, neurodermatitis)

• seborrheic dermatitis

• dry skin

Contraindications

Hypersensitivity, children under 1 year of age.

Method of administration and dosage

The drug is intended for external use.

Used in adults and children from 1 year old.

The cream is applied in a thin layer to the affected areas 2-3 times a day.

Duration of treatment for:

• psoriasis - 1-1.5 months, repeated courses - when signs of exacerbation appear;

• atopic dermatitis - 3-4 weeks;

• seborrheic dermatitis - 2 weeks;

Side effect

The drug is usually well tolerated. Allergic reactions are sometimes noted.

Overdose

To date, no cases of zinc pyrithione overdose have been reported.

Interaction with other medicinal products

No clinically significant interaction of zinc pyrithione with other drugs has been identified.

Release form

Cream for external use 0.2%.

25 g or 50 g in aluminum tubes. The tube, together with the instructions for use, is placed in a cardboard box.

Storage conditions

In a dry place, at a temperature of 4 to 25 ? C. Keep out of the reach of children.

Shelf life

3 years. Do not use after the expiration date printed on the package.

Conditions of dispensing from pharmacies

Without recipe.

Marketing Authorization Holder / Consumer Claims Organization

PJSC 'Otisipharm', Russia, 123317, Moscow, st. Test, 10

Tel .: +7 (800) 775-98-19 Fax: +7 (495) 221-18-02 www: otcpharm.ru

Manufacturer

OJSC 'Pharmstandard-Tomskkhimfarm'