xylometazoline | Xylen nasal spray 0.05% 10 ml

Latin name

Xylen

Release form

Nasal spray.

Packing

Bottle of 10 ml.

Pharmacological action

Xenical is a potent, specific and reversible inhibitor of gastrointestinal lipases with a long-lasting effect. Its therapeutic effect is carried out in the lumen of the stomach and small intestine and consists in the formation of a covalent bond with the active serine region of the gastric and pancreatic lipases.

Inactivated enzyme at the same time loses its ability to break down food fats, which come in the form of triglycerides, Its therapeutic effect is carried out in the lumen of the stomach and small intestine and consists in the formation of a covalent bond with the active serine region of the gastric and pancreatic lipases.

The inactivated enzyme loses its ability to break down food fats, which come in the form of triglycerides, into absorbable free fatty acids and monoglycerides.

Since undigested triglycerides are not absorbed, the resulting reduction in calorie intake leads to a decrease in body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation.

Judging by the results of the fat content in feces, the effect of orlistat begins 24-48 hours after ingestion. After discontinuation of the drug, the fat content in feces after 48-72 hours usually returns to the level reduces swelling of the nasal mucosa and the amount of secretion secreted, restores patency of the nasal passages, facilitates nasal breathing.

Indications

Acute allergic rhinitis, sinusitis, hay fever, otitis media (to reduce swelling of the nasopharyngeal mucosa), preparing the patient for diagnostic procedures in the nasal passages.

Contraindications

Angle-closure glaucoma, atrophic rhinitis, arterial hypertension, tachycardia, severe atherosclerosis, hyperthyroidism, surgical interventions on the meninges (history), hypersensitivity to xylometazoline.

Use during pregnancy and lactation

During pregnancy and lactation, it should be used only after a careful assessment of the risk-benefit ratio for the mother and the fetus, it is not allowed to exceed the recommended doses.

Ingredients

1 ml spray contains:

Active ingredient:

xylometazoline hydrochloride - 0.0005 g

Excipients:

benzalkonium chloride (in terms of anhydrous),

disodium hydrogen phosphate, sodium phosphate disodium hydrogen phosphate dodecahydrate,

sodium chloride,

purified water.

Dosage and administration of

Children under 6 years of age - 1-2 injections 0, 05% solution in each nasal passage 1-2 times a day for 3-5 days (no more).

Side effects

With frequent and / or prolonged use: irritation of the mucosa, burning, tingling, sneezing, dry nasal mucosa, hypersecretion.

Rarely: swelling of the nasal mucosa (more often with prolonged use), palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disturbances, and visual impairment.

With prolonged use in high doses: depressed.

Drug Interaction

Incompatible with monoamine oxidase (MAO) inhibitors and tricyclic antidepressants.

Overdose

Symptoms: increased side effects.

Treatment: symptomatic under the supervision of a physician.

Storage conditions

In a dry, dark place.

Expiration

3 years.

Deystvuyuschee substances

xylometazoline

Pharmacy leave conditions

Over-the-counter

dosage form

dosage form

nasal spray