Ximedon tablets 250mg, No. 50

In the complex therapy of the following diseases:

- deep and superficial burns (preparation of patients for autodermoplasty),

- long-term non-healing wounds, trophic ulcers,

- peptic ulcer of the stomach and duodenum,

- bedsores,

- frostbite,

- purulent-inflammatory diseases of soft tissues and bones,

- chronic osteomyelitis,

- streptococcal infections (tonsillitis, erysipelas),

- microbial eczema,

- psoriasis,

- viral hepatitis,

- pulmonary tuberculosis,

- pneumonia, chronic bronchitis,

- chronic cystic sinusitis,

- salmonellosis,

- rheumatism,

- deep vein thrombophlebitis of the lower extremities,

- pre- and postoperative periods for the prevention of pyo-inflammatory complications of postoperative wounds, especially in patients with a high risk of failure of the abdominal wall sutures (anemia, diabetes mellitus, etc.) and the gastrointestinal tract.

Apply orally before meals.

For deep and superficial burns (preparing patients for autodermoplasty) - 0.5 g 3 times a day for 20 days.

When carrying out skin-plastic operations, the drug is prescribed before and after the operation for 10 days.

For long-term non-healing wounds, trophic ulcers, bedsores - 0.5 g 3 times a day for 25-30 days.

For gastric ulcer and duodenal ulcer - 0.5 g 2 times a day for 12 days.

In case of frostbite - 0.25-0.5 g 3-4 times a day for 2-5 weeks.

For purulent-inflammatory diseases of soft tissues and bones - 0.5 g 4 times a day for 10-30 days.

In chronic osteomyelitis - before and after surgery, 0.5 g 4 times a day for 20-25 days. Repeated courses of treatment are carried out after 6 months for 1.5 years.

For angina, erysipelas - 0.5 g 3 times a day for 7-10 days.

With microbial eczema - 0.5 g 3 times a day for 10 days.

With psoriasis - 0.5 g 3 times a day for 2-3 weeks.

For viral hepatitis B and C - 0.5 g 3 times a day for 10 days.

With pulmonary tuberculosis - 0.5 g 4 times a day for 2 months.

With pneumonia and chronic bronchitis - 0.5 g 4 times a day for 18-21 days.

In chronic cystic sinusitis - 0.25-0.5 g 4 times a day for 1 month.

With salmonellosis - 0.5 g 3 times a day for 7 days.

For rheumatism - 0.5 g 3 times a day for 3-4 weeks.

In the pre- and postoperative periods for the prevention of pyo-inflammatory complications of postoperative wounds, especially in patients with a high risk of failure of the abdominal wall sutures (anemia, diabetes mellitus, etc.) and the gastrointestinal tract - 0.5 g 4 times a day for 10-20 days (from the first day after the operation or in the preoperative period 3-5 days and then from the first day after the operation).

per tablet: Active substance - xymedon 0.25 g. Excipients - calcium stearate, potato starch, talc

• hypersensitivity.

• Leukemia (acute and chronic),

• erythremia,

• children under 18 years of age.

• With caution: Patients with diabetes mellitus should more often determine glucose tolerance, due to a possible decrease in insulin requirements

Pharmacodynamics

Xymedon accelerates the processes of tissue regeneration and shortens the healing time of the burn surface, improves engraftment of skin grafts during autodermoplasty. Contributes to the normalization of the ratio between the content of fibrinogen in the blood and its fibrinolytic activity, improves regional blood circulation. Normalizes the immune system, increases the phagocytic activity of T-lymphocytes and nonspecific resistance of the body. Stimulates erythro- and leukopoiesis, cellular and humoral defense factors, has anti-inflammatory and antimicrobial effects.

Pharmacokinetics

When taken orally, xymedon is rapidly absorbed within 0.5-1 h; the maximum concentration of the drug in the blood serum is reached after 1.7 hours. The half-life of the drug is 5.5 hours. As a result of the low percentage of binding with serum albumin (9%) and the absence of biotransformation in the body, the drug does not have a competitive effect when taking other drugs ...

Application during pregnancy and during breastfeeding

The use of the drug is indicated only in cases where the intended benefit to the mother outweighs the potential risk to the fetus. During the period of treatment, it is necessary to resolve the issue of stopping breastfeeding.

Side effect:

Possible - dyspepsia, allergic reactions.

Overdose:

Due to the low toxicity and the large breadth of the therapeutic action of xymedon, no cases of toxic manifestations were observed.

Interaction with other medicinal products

Incompatibility of xymedon with any medicinal products has not been identified. Can be combined with anabolic steroids, chemical and biological antiseptics.

Influence on the ability to drive a car and equipment

The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.