Wessel duet f capsules 250LE, No. 60

angiopathies with an increased risk of thrombus formation, incl. after myocardial infarction;

disorders of cerebral circulation, including the acute period of ischemic stroke and the period of early recovery;

discirculatory encephalopathy due to atherosclerosis, diabetes mellitus, hypertension;

vascular dementia;

occlusive lesions of peripheral arteries of atherosclerotic and diabetic genesis;

phlebopathy, deep vein thrombosis;

microangiopathy (nephropathy, retinopathy, neuropathy) and macroangiopathy (diabetic foot syndrome, encephalopathy, cardiopathy) in diabetes mellitus;

thrombophilic conditions, antiphospholipid syndrome (together with acetylsalicylic acid, as well as after low molecular weight heparins);

treatment of heparin-induced thrombotic thrombocytopenia (HTT), since the drug does not cause or aggravate HTT.

In / m, in / in (in 150-200 ml of saline), inside. At the beginning of treatment, the contents of 1 ampoule should be injected daily intramuscularly for 15Ц20 days, then 1 caps. 2 times a day inside between meals for 30-40 days. The full course should be repeated at least 2 times a year. At the discretion of the doctor, the dosage regimen can be changed.

Solution for injection 1 amp. Sulodexide 600 LE Auxiliary substances: sodium chloride - 18 mg; water for preparation of injections - qs up to 2 ml

in ampoules of 2 ml; in a box of 10 ampoules.

Capsules 1 capsule sulodexide 250 LE Auxiliary substances: sodium lauryl sulfate - 3.3 mg; colloid of silicon dioxide - 3.0 mg; triglycerides - 86.1 mg capsule composition: gelatin - 55.0 mg; glycerin - 21.0 mg; sodium ethyl p-oxybenzoate - 0.24 mg; sodium propyl paraoxybenzoate - 0.12 mg; titanium dioxide (E171) - 0.30 mg; red iron oxide - 0.90 mg

in a blister 25 pcs.; 2 blisters in a box.

hypersensitivity;

hemorrhagic diathesis and diseases accompanied by decreased blood coagulability;

pregnancy (I trimester).

Pharmachologic effect:

Wessel Douai F is an angioprotective, profibrinolytic, antithrombotic agent.

Indications:

• angiopathies with an increased risk of thrombus formation, including after myocardial infarction;

• violation of cerebral circulation, including the acute period of ischemic stroke and the period of early recovery; discirculatory encephalopathy due to atherosclerosis, diabetes mellitus, hypertension; vascular dementia;

• occlusive lesions of peripheral arteries of both atherosclerotic and diabetic genesis;

• phlebopathy, deep vein thrombosis;

• microangiopathy (nephropathy, retinopathy, neuropathy) and macroangiopathy in diabetes mellitus (diabetic foot syndrome, encephalopathy, cardiopathy);

• thrombophilic conditions, antiphospholipid syndrome (prescribed in conjunction with acetylsalicylic acid, as well as after low molecular weight heparins);

• treatment of heparin-induced thrombotic thrombocytopenia, since it does not cause or aggravate it.

Contraindications:

• hypersensitivity;

• hemorrhagic diathesis and diseases accompanied by decreased blood coagulability;

• pregnancy I trimester.

Method of administration and dosage:

1-2 capsules 2 times a day before meals for 30-40 days. Usually, treatment begins with the use of the drug in the dosage form 'solution for intravenous and intramuscular use', 1 ampoule per day, intramuscularly or intravenously, for 15-20 days.

The full course of treatment should be repeated at least 2 times a year.

Side effects:

Nervous system: infrequently - headache, very rarely - loss of consciousness.

Hearing organ: often - dizziness.

Gastrointestinal tract: often - pain in the upper abdomen, diarrhea, nausea, infrequently - abdominal discomfort, dyspepsia, flatulence, vomiting, very rarely - stomach bleeding.

Allergic reactions: often - skin rash of various localization, infrequently - eczema, erythema, urticaria.

Overdose:

Bleeding is the only occurrence that can occur with an overdose. If bleeding develops, it is necessary to administer protamine sulfate (1% solution), which is used for bleeding caused by heparin.