Vitamin E capsules 100mg, No. 10

Hypovitaminosis E.

In complex therapy: muscular dystrophies; dermatomyositis; atherosclerosis, myocardial dystrophies; menstrual irregularities; threats of termination of pregnancy, dysfunction of the sex glands in men; dermatoses, psoriasis.

Inside, 100-300 mg / day, if necessary, up to 1 g / day.

For diseases of the neuromuscular system - 100 mg per day for 1-2 months. Repeated courses in 2-3 months.

In case of spermatogenesis and potency disorders - 100 - 300 mg per day in combination with hormonal therapy for a month.

With threatening abortion - 100 mg per day for 7-14 days, with the usual abortion and deterioration of intrauterine development of the fetus - 100 mg per day for the first 2-3 months of pregnancy every day or every other day.

For peripheral vascular diseases, myocardial dystrophy, atherosclerosis - 100 mg per day (with vitamin A) for 20 - 40 days, after 3-6 months the course of treatment can be repeated.

In dermatology - 100 mg per day for 20 - 40 days.

1 caps. vitamin E (tocopherol acetate) 100 mg

Excipients: sunflower oil - 100 mg.

The composition of the capsule shell: gelatin - 44.73 mg, glycerol - 14.67 mg, methyl parahydroxybenzoate - 0.29 mg, azorubin dye - 0.31 mg.

Individual hypersensitivity to the components of the drug, acute myocardial infarction, childhood.

With caution: hypoprothrombinemia, severe cardiosclerosis, myocardial infarction, increased risk of thromboembolism.

pharmachologic effect

Vitamin E is an antioxidant. Protects the cell membranes of body tissues from oxidative changes; stimulates the synthesis of heme and heme-containing enzymes - hemoglobin, myoglobin, cytochromes, catalase, peroxidase. Inhibits the oxidation of unsaturated fatty acids and selenium. Inhibits cholesterol synthesis. Prevents hemolysis of erythrocytes, increased permeability and fragility of capillaries, dysfunction of seminiferous tubules and testicles, placenta, normalizes reproductive function.

Indications

Hypovitaminosis E.

In complex therapy: muscular dystrophies; dermatomyositis; atherosclerosis, myocardial dystrophies; menstrual irregularities; threats of termination of pregnancy, dysfunction of the sex glands in men; dermatoses, psoriasis.

Contraindications

Individual hypersensitivity to the components of the drug, acute myocardial infarction, childhood. With caution: hypoprothrombinemia, severe cardiosclerosis, myocardial infarction, increased risk of thromboembolism.

Application during pregnancy and lactation

The drug in this dosage is not recommended for use in the normal course of pregnancy. For pregnant and lactating mothers, the recommended dose of vitamin E is 10-14 mg.

Composition

1 caps. vitamin E (tocopherol acetate) 100 mg

Excipients: sunflower oil - 100 mg.

The composition of the capsule shell: gelatin - 44.73 mg, glycerol - 14.67 mg, methyl parahydroxybenzoate - 0.29 mg, azorubin dye - 0.31 mg.

Method of administration and dosage

Inside, 100-300 mg / day, if necessary, up to 1 g / day. For diseases of the neuromuscular system - 100 mg per day for 1-2 months. Repeated courses in 2-3 months. In case of spermatogenesis and potency disorders - 100 - 300 mg per day in combination with hormonal therapy for a month. With threatening abortion - 100 mg per day for 7-14 days, with the usual abortion and deterioration of intrauterine development of the fetus - 100 mg per day for the first 2-3 months of pregnancy every day or every other day. For peripheral vascular diseases, myocardial dystrophy, atherosclerosis - 100 mg per day (with vitamin A) for 20 - 40 days, after 3-6 months the course of treatment can be repeated. In dermatology - 100 mg per day for 20 - 40 days.

Side effects

Allergic reactions, dyspepsia are possible.

Drug interactions

Vitamin E enhances the effect of glucocorticosteroid drugs, non-steroidal anti-inflammatory drugs, cardiac glycosides. Reduces the effectiveness and toxicity of vitamins A and D. Increases the effectiveness of antiepileptic drugs in patients with epilepsy. The simultaneous use of other multivitamin complexes containing vitamin E is not recommended in order to avoid overdose. The simultaneous intake of large doses of vitamin E with iron, vitamin K, or anticoagulants (drugs that prevent blood clotting), increases the time of blood clotting.

Overdose

Symptoms: when taking vitamin E for a long period at doses of 400-800 mg / day: - blurred vision, dizziness, headache, nausea, fatigue, diarrhea, gastralgia, asthenia.

When taking more than 800 mg / day for a long period - an increase in the risk of bleeding in patients with hypovitaminosis K, impaired metabolism of thyroid hormones, disorders of sexual function, thrombophlebitis, thromboembolism, necrotizing colitis, sepsis, hyperbilirubinemia, renal failure, retinal hemorrhage , hemorrhagic stroke, ascites. Treatment: symptomatic. Cancellation of the drug, the appointment of glucocorticosteroid drugs.

Storage conditions

Store in a dry, dark place at a temperature not exceeding 25 ? C. Keep out of the reach of children.

Shelf life is 2 years. Do not use after the expiration date.