Vibrocil nasal drops 15ml
Category
Runny nose
Scope of the medicinal product
Ear, Throat, Nose
Release form
Drops
Manufacturer country
Switzerland
Package quantity, pcs
one
Release form, composition and packaging
?
Nasal drops in the form of a clear solution from colorless to slightly yellow, with a faint lavender scent.
1 ml
phenylephrine 2.5 mg
dimethindene maleate 0.25 mg
benzalkonium chloride 50% solution (in terms of benzalkonium chloride) - 0.2 mg (0.1 mg), citric acid monohydrate - 2.6 mg, sodium hydrogen phosphate - 4.4 mg, sorbitol - 35 mg, lavender oil - 0.2 mg, water - up to 1 ml.
15 ml - dark glass bottles (1) complete with pipette cap - cardboard packs.
pharmachologic effect
Vibrocil® is a combined preparation containing phenylephrine and dimethindene.
Phenylephrine is a sympathomimetic, when applied topically, it has a moderate vasoconstrictor effect (due to stimulation of β 1-adrenergic receptors located in the venous vessels of the nasal mucosa), eliminates edema of the nasal mucosa and its paranasal sinuses.
Dimetindene is an antiallergic agent - an antagonist of histamine H1 receptors
does not reduce the activity of the ciliated epithelium of the nasal mucosa.
Pharmacokinetics
Vibrocil® is intended for local use, and its activity does not depend on the concentration of active substances in the blood plasma.
Indications for use
- Acute rhinitis (including colds)
- allergic rhinitis (including hay fever)
- vasomotor rhinitis
- chronic rhinitis
- acute and chronic sinusitis
- Acute otitis media (as an adjuvant)
- preparation for surgical interventions in the nasal area and elimination of edema of the nasal mucosa and paranasal sinuses after surgery in this area.
Contraindications for use
- atrophic rhinitis (including with fetid discharge - ozena) - simultaneous administration of MAO inhibitors and a period up to 14 days after their cancellation - angle-closure glaucoma - children's age up to 1 year - hypersensitivity to phenylephrine, dimethindene maleate or other components of the drug. The drug should be used with caution in cardiovascular diseases (arterial hypertension, arrhythmias, generalized atherosclerosis), hyperthyroidism, prostate adenoma, diabetes mellitus, obstruction of the bladder neck (for example, due to prostatic hypertrophy), epilepsy. As in the case of the use of any local vasoconstrictor drugs, care should be taken when prescribing Vibrocil® to patients with severe reactions to sympathomimetics, manifested in the form of insomnia, dizziness, tremor,cardiac arrhythmias or increased blood pressure.
Dosage regimen
Children under 1 year of age: Contraindicated.
Children aged 1 to 6 years (under the supervision of adults): 1-2 drops in each nasal passage 3-4 times / day.
Children aged 6 to 12 years (under the supervision of adults): 3-4 drops in each nasal passage 3-4 times / day.
For adolescents over the age of 12 and adults: 3-4 drops in each nasal passage 3-4 times / day.
It is recommended to thoroughly clean the nasal passages before use
buried in the nose, head thrown back.
This head position is maintained for several minutes.
The drug should not be used continuously for more than 7 days.
If symptoms persist, you should consult your doctor.
Overdose
An overdose of Vibrocil® can cause sympathomimetic effects, for example, heart palpitations, premature contraction of the ventricles of the heart, headache in the occiput, tremors, fatigue, increased blood pressure, emotional arousal, insomnia, pallor of the skin.
The drug can also cause mild sedation, dizziness, stomach pain, nausea, and vomiting.
Treatment: the use of activated carbon, laxatives in young children
in adults and children over 6 years old - taking a large amount of liquid.
There is no specific antidote.
Increased blood pressure, call
Name ENG
VIBROCIL
Clinical and pharmacological group
A drug with a vasoconstrictor and antiallergic effect for local use in ENT practice
ATX code
Phenylephrine in combination with other drugs
Dosage
15ml
Structure
Excipients: benzalkonium chloride 50% solution (in terms of benzalkonium chloride) - 0.2 mg (0.1 mg), citric acid monohydrate - 2.6 mg, sodium hydrogen phosphate - 4.4 mg, sorbitol - 35 mg, lavender oil - 0.2 mg, water - up to 1 ml.
Indications
acute rhinitis (including with colds)
allergic rhinitis (including hay fever)
vasomotor rhinitis
chronic rhinitis
acute and chronic sinusitis
acute otitis media (as an adjuvant)
preparation for surgical interventions in the nasal area and elimination of edema of the nasal mucosa and paranasal sinuses after surgery in this area.
Storage conditions and periods
At a temperature not higher than 30 degrees.
Expiration date: 3 years
Contraindications
hypersensitivity to drug components,
atrophic rhinitis (including fetid discharge - ozena),
simultaneous administration of MAO inhibitors and a period up to 14 days after their cancellation,
children under 6 years old,
pregnancy and lactation.,
With care: in case of cardiovascular diseases (arterial hypertension, arrhythmias, generalized atherosclerosis), thyroid diseases, angle-closure glaucoma, benign prostatic hyperplasia, insulin-dependent diabetes mellitus.,
Precaution: in patients with severe reactions to sympathomimetics such as insomnia and dizziness.
INN / Active ingredient
Phenylephrine + Dimethindene
Specifications
Category
Runny nose
Scope of the medicinal product
Ear, Throat, Nose
Release form
Drops
Manufacturer country
Switzerland
Package quantity, pcs
one
Minimum age from
1 year
Way of introduction
Through the respiratory tract
Vacation conditions
Without recipe
Volume, ml.
15 ml
Brand name
Vibrocil
The amount of the dosage form in the primary package
15 ml
Primary packaging type
Bottle
Type of consumer packaging
Pack of cardboard
Anatomical and therapeutic characteristics
R01AB01 Phenylephrine, in combination with other drugs
Dosage form
Nasal drops
Expiration date in days
1095
Dosage (volume) of the substance in the preparation
2.5 mg + 0.25 mg / 1 ml
The target audience
Children
Package weight, g
15
Mode of application
:
Children under 1 year of age: Contraindicated.
Children aged 1 to 6 years (under the supervision of adults): 1-2 drops in each nasal passage 3-4 times / day.
Children aged 6 to 12 years (under the supervision of adults): 3-4 drops in each nasal passage 3-4 times / day.
For adolescents over the age of 12 and adults: 3-4 drops in each nasal passage 3-4 times / day.
It is recommended to thoroughly clean the nasal passages before use
buried in the nose, head thrown back.
This head position is maintained for several minutes.
The drug should not be used continuously for more than 7 days.
If symptoms persist, you should consult your doctor.
Pharmaco-therapeutic group
:
Combined antiallergic agent (H1-histamine receptor blocker + alpha-adrenergic agonist)
Information on technical characteristics, delivery set, country of manufacture