Vibrocil nasal drops 15ml

Release form, composition and packaging

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Nasal drops in the form of a clear solution from colorless to slightly yellow, with a faint lavender scent.

1 ml

phenylephrine 2.5 mg

dimethindene maleate 0.25 mg

benzalkonium chloride 50% solution (in terms of benzalkonium chloride) - 0.2 mg (0.1 mg), citric acid monohydrate - 2.6 mg, sodium hydrogen phosphate - 4.4 mg, sorbitol - 35 mg, lavender oil - 0.2 mg, water - up to 1 ml.

15 ml - dark glass bottles (1) complete with pipette cap - cardboard packs.

pharmachologic effect

Vibrocil® is a combined preparation containing phenylephrine and dimethindene.

Phenylephrine is a sympathomimetic, when applied topically, it has a moderate vasoconstrictor effect (due to stimulation of β 1-adrenergic receptors located in the venous vessels of the nasal mucosa), eliminates edema of the nasal mucosa and its paranasal sinuses.

Dimetindene is an antiallergic agent - an antagonist of histamine H1 receptors

does not reduce the activity of the ciliated epithelium of the nasal mucosa.

Pharmacokinetics

Vibrocil® is intended for local use, and its activity does not depend on the concentration of active substances in the blood plasma.

Indications for use

- Acute rhinitis (including colds)

- allergic rhinitis (including hay fever)

- vasomotor rhinitis

- chronic rhinitis

- acute and chronic sinusitis

- Acute otitis media (as an adjuvant)

- preparation for surgical interventions in the nasal area and elimination of edema of the nasal mucosa and paranasal sinuses after surgery in this area.

Contraindications for use

- atrophic rhinitis (including with fetid discharge - ozena) - simultaneous administration of MAO inhibitors and a period up to 14 days after their cancellation - angle-closure glaucoma - children's age up to 1 year - hypersensitivity to phenylephrine, dimethindene maleate or other components of the drug. The drug should be used with caution in cardiovascular diseases (arterial hypertension, arrhythmias, generalized atherosclerosis), hyperthyroidism, prostate adenoma, diabetes mellitus, obstruction of the bladder neck (for example, due to prostatic hypertrophy), epilepsy. As in the case of the use of any local vasoconstrictor drugs, care should be taken when prescribing Vibrocil® to patients with severe reactions to sympathomimetics, manifested in the form of insomnia, dizziness, tremor,cardiac arrhythmias or increased blood pressure.

Dosage regimen

Children under 1 year of age: Contraindicated.

Children aged 1 to 6 years (under the supervision of adults): 1-2 drops in each nasal passage 3-4 times / day.

Children aged 6 to 12 years (under the supervision of adults): 3-4 drops in each nasal passage 3-4 times / day.

For adolescents over the age of 12 and adults: 3-4 drops in each nasal passage 3-4 times / day.

It is recommended to thoroughly clean the nasal passages before use

buried in the nose, head thrown back.

This head position is maintained for several minutes.

The drug should not be used continuously for more than 7 days.

If symptoms persist, you should consult your doctor.

Overdose

An overdose of Vibrocil® can cause sympathomimetic effects, for example, heart palpitations, premature contraction of the ventricles of the heart, headache in the occiput, tremors, fatigue, increased blood pressure, emotional arousal, insomnia, pallor of the skin.

The drug can also cause mild sedation, dizziness, stomach pain, nausea, and vomiting.

Treatment: the use of activated carbon, laxatives in young children

in adults and children over 6 years old - taking a large amount of liquid.

There is no specific antidote.

Increased blood pressure, call

Name ENG

VIBROCIL

Clinical and pharmacological group

A drug with a vasoconstrictor and antiallergic effect for local use in ENT practice

ATX code

Phenylephrine in combination with other drugs

Dosage

15ml

Structure

Excipients: benzalkonium chloride 50% solution (in terms of benzalkonium chloride) - 0.2 mg (0.1 mg), citric acid monohydrate - 2.6 mg, sodium hydrogen phosphate - 4.4 mg, sorbitol - 35 mg, lavender oil - 0.2 mg, water - up to 1 ml.

Indications

acute rhinitis (including with colds)

allergic rhinitis (including hay fever)

vasomotor rhinitis

chronic rhinitis

acute and chronic sinusitis

acute otitis media (as an adjuvant)

preparation for surgical interventions in the nasal area and elimination of edema of the nasal mucosa and paranasal sinuses after surgery in this area.

Storage conditions and periods

At a temperature not higher than 30 degrees.

Expiration date: 3 years

Contraindications

hypersensitivity to drug components,

atrophic rhinitis (including fetid discharge - ozena),

simultaneous administration of MAO inhibitors and a period up to 14 days after their cancellation,

children under 6 years old,

pregnancy and lactation.,

With care: in case of cardiovascular diseases (arterial hypertension, arrhythmias, generalized atherosclerosis), thyroid diseases, angle-closure glaucoma, benign prostatic hyperplasia, insulin-dependent diabetes mellitus.,

Precaution: in patients with severe reactions to sympathomimetics such as insomnia and dizziness.

INN / Active ingredient

Phenylephrine + Dimethindene

Specifications

Category

Runny nose

Scope of the medicinal product

Ear, Throat, Nose

Release form

Drops

Manufacturer country

Switzerland

Package quantity, pcs

one

Minimum age from

1 year

Way of introduction

Through the respiratory tract

Vacation conditions

Without recipe

Volume, ml.

15 ml

Brand name

Vibrocil

The amount of the dosage form in the primary package

15 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

R01AB01 Phenylephrine, in combination with other drugs

Dosage form

Nasal drops

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

2.5 mg + 0.25 mg / 1 ml

The target audience

Children

Package weight, g

15

Mode of application

:

Children under 1 year of age: Contraindicated.

Children aged 1 to 6 years (under the supervision of adults): 1-2 drops in each nasal passage 3-4 times / day.

Children aged 6 to 12 years (under the supervision of adults): 3-4 drops in each nasal passage 3-4 times / day.

For adolescents over the age of 12 and adults: 3-4 drops in each nasal passage 3-4 times / day.

It is recommended to thoroughly clean the nasal passages before use

buried in the nose, head thrown back.

This head position is maintained for several minutes.

The drug should not be used continuously for more than 7 days.

If symptoms persist, you should consult your doctor.

Pharmaco-therapeutic group

:

Combined antiallergic agent (H1-histamine receptor blocker + alpha-adrenergic agonist)

Information on technical characteristics, delivery set, country of manufacture