Vetmedin 1.25mg for the treatment of heart failure with meat flavor 50 tablets

DESCRIPTION

Vetmedin (Vetmedin) - a drug for the treatment of heart failure in dogs. In appearance, the drug is an oval-shaped tablet, rough, brown in color with white blotches, the company logo, symbols and a line for breaking into two equal parts.

COMPOSITION

1 tablet of the drug contains 1.25 mg of pimobendan as an active ingredient (DV), respectively, as well as auxiliary substances: anhydrous citric acid, croscarmellose sodium, maize starch, lactose monohydrate, povidone 25, meat flavoring, colloidal anhydrous silicon and stearate magnesium.

PHARMACOLOGICAL PROPERTIES

Pharmacotherapeutic group: cardiotonic agent.

Pimobendan, which is part of the drug Vetmedin, has a positive inotropic and pronounced vasodilating effect. In contrast to cardiac glycosides, the positive inotropic effect of the drug is due to an increase in the sensitivity of cardiac muscle fibers to calcium. The vasodilating effect is associated with inhibition of the activity of phosphodiesterase III. Due to the presence of a positive inotropic and vasodilating effect in heart failure, the drug increases the force of heart contractions and reduces both preload and afterload.

After oral administration, pimobendan is rapidly absorbed into the bloodstream, its bioavailability is 60 - 63%; the half-life of the compound in blood plasma is 0.4 В± 0.1 hours, and the half-life of its active metabolite is 2.0 В± 0.3 hours. Most of the metabolites of pimobendan are excreted from animals through bile in the faeces.

According to the degree of impact on the body, Vetmedin belongs to low-hazard substances (hazard class 4 in accordance with GOST 12.1.007-76), does not possess sensitizing, embryotoxic, teratogenic and mutagenic properties.

PURPOSE

Vetmedin is used in dogs to treat heart failure caused by dilated cardiomyopathy, bicuspid or tricuspid valve insufficiency, which is accompanied by characteristic symptoms: cough, shortness of breath, fainting, decreased activity, exercise intolerance or ascites.

DOSAGE AND APPLICATION

Vetmedin is administered to animals orally 1 hour before feeding. The dose of the drug is prescribed by the veterinarian, depending on the severity of the disease and the condition of the animal.

The daily dose of pimobendan (DV) ranges from 0.2 mg to 0.6 mg per 1 kg of animal body weight and is divided into two doses.

Vetmedin is available in the form of tablets or capsules. The daily dose is divided into 2 doses and given 1 hour before feeding in the morning and evening. For details, see the instructions for use.

For a more accurate determination of the dose corresponding to the weight of the animal, the tablet can be divided along the break line into halves.

With congestive heart failure, dogs are used for life with the selection of an individual dose.

SPECIAL INSTRUCTIONS

In case of an overdose of Vetmedin, the animal may experience vomiting, apathy, tachycardia, heart murmurs and a decrease in pressure. In this case, the use of the drug is discontinued and adsorbents (for example, activated carbon) are immediately prescribed to the animal.

The peculiarities of the action of the drug during the first administration or upon its withdrawal were not revealed.

Puppy and lactating bitches Vetmedin is used for health reasons under the supervision of the attending veterinarian if the potential risk to the mother outweighs the risk to the fetus and puppies.

CONTRAINDICATIONS

A contraindication to the use of the drug is the animal's hypersensitivity to its components.

It is prohibited to use Vetmedin in hypertrophic cardiomyopathy and clinical conditions in which cardiac output cannot be increased due to functional or anatomical features (for example, aortic stenosis), in severe liver damage, due to the fact that the drug is mainly metabolized in the liver ...

SIDE EFFECTS

As a rule, side effects and complications when using the drug Vetmedin in accordance with this instruction are not observed. With increased individual sensitivity and the manifestation of allergic reactions, the use of the drug is discontinued and the animal is prescribed means of symptomatic therapy.

SHELF LIFE AND STORAGE

The shelf life of the drug Vetmedin, subject to storage conditions, is 3 years from the date of production. Do not use the drug after the expiration date.

Vetmedin is stored in closed manufacturer's packaging separately from food and feed in a dry, dark place at a temperature of 8 В° C to 25 В° C.

PACKAGING

Vetmedin is produced in packs of 50 tablets in plastic bottles of appropriate capacity. Vials together with instructions for use are packed in individual cardboard boxes.

Specifications

Bonus points

0

KolVUP

1

Manufacturer

Boehringer

Temperature regime

from +8 to +25

Teaser

for the treatment of heart failure in dogs