Venoruton Capsules, for venous insufficiency, 300 mg, 50 pieces

Special Price $46.80 Regular Price $62.00
In stock
SKU
OTC102028867

Category

Diseases of the veins

Scope of the medicinal product

Heart, vessels, blood

Release form

Capsules

Manufacturer country

India

Package quantity, pcs

fifty

Description

Release form

Capsules

Packaging

50 pcs.

pharmachologic effect

Venoruton is a drug with venotonic and angioprotective effects.

Derivative routine.

Acts mainly on capillaries and veins.

Reduces the pores between endothelial cells by modifying the fibrous matrix located between endothelial cells.

Inhibits aggregation and increases the degree of deformability of erythrocytes.

Has anti-inflammatory effect.

In chronic venous insufficiency Venoruton reduces the severity of its manifestations such as edema, pain, convulsions, trophic disorders, varicose ulcers.

Reduces the symptoms associated with hemorrhoids, incl.

pain, itching and bleeding.

Providing a beneficial effect on the permeability and resistance of the capillary walls, the drug helps to slow down the development of diabetic retinopathy.

Due to the effect of rutoside on the rheological properties of blood, the drug helps prevent retinal microthrombosis.

Pharmacokinetics

Absorption and distribution

After oral administration, absorption is about 10-15%.

Cmax in blood plasma is reached within 1-9 hours.

Within 120 hours, concentrations remain detectable

their decrease occurs biexponentially.

Withdrawal

T1 / 2 is 10-25 hours. O - (? - hydroxyethyl) -rutosides and their glucuronic metabolites are excreted mainly in the bile, 3-6% is excreted by the kidneys within 48 hours.

Indications

Chronic venous insufficiency and varicose veins (heaviness and pain in the legs, swelling, convulsions, trophic disorders, varicose dermatitis, ulcers, etc.)

pain after sclerotherapy, hemorrhoids (symptomatic treatment), venous insufficiency and hemorrhoids during pregnancy (starting from the 4th month)

Contraindications

Hypersensitivity to rutosides or other components of the drug

I trimester of pregnancy.

Application during pregnancy and lactation

In the course of clinical studies, the use of Venoruton during pregnancy was studied, however, its use in the first trimester was not specifically studied.

Use in the first trimester of pregnancy is contraindicated.

In studies conducted on animals, no teratogenic and other undesirable effects of the drug on the fetus were noted.

It is recommended to prescribe Venoruton inside only starting from the second trimester of pregnancy, when the expected benefit to the mother from its use outweighs the possible risk to the fetus.

special instructions

If the severity of the symptoms of the disease does not decrease with the use of the drug, it is recommended to verify the diagnosis.

Structure

1 capsule contains:

Active ingredient: hydroxyethylrutosides 300 mg,

Excipient: macrogol 6000 - 9 mg

Empty hard gelatin capsule: gelatin - about 63.0097 mg

water - 11.02 mg

titanium dioxide - about 1.5 mg

iron dye yellow oxide - about 0.47 mg.

The capsule is printed with black ink, the capsule contains trace amounts of ink

Main ingredients of printing inks: shellac in ethanol

iron dye black oxide

n-butanol

propylene glycol

isopropanol

ammonia water.

Method of administration and dosage

Inside, during meals, swallowing whole with water.

For chronic venous insufficiency, postphlebitic syndrome, trophic disorders with varicose veins and trophic ulcers: at the initial stage of treatment (within the first 2 weeks), take 1 capsule Venoruton 2-3 times a day (no more than 3 capsules per day).

Further treatment is either continued for 2-3 months at the same dose as maintenance therapy, or is stopped.

The minimum maintenance dose is 1 capsule 2 times a day.

In this case, the achieved therapeutic effect lasts for at least 4 weeks.

The minimum course of treatment, during which the effect usually develops, is 2 weeks.

To maintain the result, it is necessary to carry out 2 courses of treatment per year.

With lymphostasis (along with bandaging with elastic bandages), as well as after sclerotherapy of veins and removal of varicose veins: the recommended dose is 10 capsules / day - 3 capsules in the morning and evening and 4 capsules at night for up to 6 months.

To eliminate the symptoms of hemorrhoids: the recommended dose is 1 capsule 2-3 times a day (no more than 3 capsules / day) until symptoms disappear, usually within 28 days.

With diabetic retinopathy, arterial hypertension and atherosclerosis (as an adjunct therapy): 2-3 capsules 2-3 times a day, not more than 3000 mg / day, for 2 months.

Side effects

From the digestive system: nausea, diarrhea, heartburn.

Allergic reactions: skin rash.

Others: headache, flushing of the face.

Side effects disappear quickly after discontinuation of the drug.

Drug interactions

The action of Venoruton is enhanced when used simultaneously with ascorbic acid.

Overdose

Overdose cases that would have been accompanied by clinical symptoms have not been reported.

Storage conditions

Store the drug in a dry, dark place at a temperature not exceeding 25 ° C.

Shelf life

3 years.

Active substance

Rutoside

Name ENG

VENORUTON

Clinical and pharmacological group

Venotonic and venoprotective drug

ATX code

Rutoside

Dosage

300mg

Structure

1 capsule contains:

Indications

Chronic venous insufficiency and varicose veins (heaviness and pain in the legs, swelling, convulsions, trophic disorders, varicose dermatitis, ulcers, etc.)

pain after sclerotherapy, hemorrhoids (symptomatic treatment), venous insufficiency and hemorrhoids during pregnancy (starting from the 4th month)

Storage conditions and periods

In a dry place, at a temperature not exceeding 30 degrees.

Expiration date: 5 years

INN / Active ingredient

Hydroxyethylrutoside

Contraindications

Hypersensitivity to rutosides or other components of the drug

I trimester of pregnancy.

Specifications

Category

Diseases of the veins

Scope of the medicinal product

Heart, vessels, blood

Release form

Capsules

Manufacturer country

India

Package quantity, pcs

fifty

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Venoruton

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Angioprotective agent

Anatomical and therapeutic characteristics

C05CA01 Rutoside

Dosage form

Capsules

Expiration date in days

1825

Dosage (volume) of the substance in the preparation

300 mg

Package weight, g

thirty

Mode of application

:

Inside, during meals, swallowing whole with water. < br> < br> For chronic venous insufficiency, postphlebitic syndrome, trophic disorders in varicose veins and trophic ulcers: at the initial stage of treatment (during the first 2 weeks), take 1 capsule Venoruton 2-3 times a day (no more than 3 capsules a day). Further treatment is either continued for 2-3 months at the same dose as maintenance therapy, or is stopped. The minimum maintenance dose is 1 capsule 2 times a day. In this case, the achieved therapeutic effect lasts for at least 4 weeks. The minimum course of treatment, during which the effect usually develops, is 2 weeks. < br> < br> To maintain the result, it is necessary to carry out 2 courses of treatment per year. < br> < br> With lymphostasis (along with bandaging with elastic bandages), as well as after sclerotherapy of veins and removal of varicose veins: the recommended dose is 10 capsules / day - 3 capsules in the morning and evening and 4 capsules at night for up to 6 months. < br> < br> To eliminate the symptoms of hemorrhoids: the recommended dose is 1 capsule 2-3 times a day (no more than 3 capsules / day) until symptoms disappear, usually within 28 days. < br> < br> For diabetic retinopathy, arterial hypertension and atherosclerosis (as an auxiliary therapy): 2-3 capsules 2-3 times a day, not more than 3000 mg / day, for 2 months.the recommended dose is 10 capsules / day - 3 capsules in the morning and evening and 4 capsules at night for up to 6 months. < br> < br> To eliminate the symptoms of hemorrhoids: the recommended dose is 1 capsule 2-3 times a day ( no more than 3 capsules / day) until the symptoms are eliminated, usually within 28 days. < br> < br> With diabetic retinopathy, arterial hypertension and atherosclerosis (as an adjuvant therapy): 2-3 capsules 2-3 times a day, no more than 3000 mg / day, for 2 months.the recommended dose is 10 capsules / day - 3 capsules in the morning and evening and 4 capsules at night for up to 6 months. < br> < br> To eliminate the symptoms of hemorrhoids: the recommended dose is 1 capsule 2-3 times a day ( no more than 3 capsules / day) until the symptoms are eliminated, usually within 28 days. < br> < br> With diabetic retinopathy, arterial hypertension and atherosclerosis (as an adjuvant therapy): 2-3 capsules 2-3 times a day, no more than 3000 mg / day, for 2 months.2-3 capsules 2-3 times a day, not more than 3000 mg / day, for 2 months.2-3 capsules 2-3 times a day, not more than 3000 mg / day, for 2 months.

Information on technical characteristics, delivery set, country of manufacture

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