Tsitovir-3 syrup for children fl. 50ml per set with a spoon dosing / measuring cap.

Release form, composition and packaging

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Colorless to yellow syrup (for children).

1 ml

alpha-glutamyl-tryptophan sodium (in terms of alpha-glutamyl-tryptophan) 0.15 mg

ascorbic acid 12 mg

bendazole hydrochloride 1.25 mg

sucrose - 800 mg, purified water - up to 1 ml.

50 ml - dark glass bottles with first opening control (1) complete with a dosing device (measuring cup or dosing spoon, or dosing pipette) - cardboard packs.

50 ml - dark glass bottles with first opening control and child protection (1) complete with a dosing device (measuring cup or dosing spoon, or dosing pipette) - cardboard packs.

pharmachologic effect

The drug, is a means of etiotropic and immunostimulating therapy, has an indirect antiviral effect against influenza A and B viruses and other viruses that cause acute respiratory viral diseases. The drug reduces the severity of the main clinical symptoms of influenza and ARVI, and also reduces the duration of the manifestation of the symptoms of the disease. Bendazol induces the production of endogenous interferon in the body, has an immunomodulatory effect (normalizes the body's immune response). Enzymes, the production of which is induced by interferon in cells of various organs, inhibit viral replication. Alpha-glutamyl-tryptophan (thymogen) is a synergist of the immunomodulatory action of bendazole, normalizing the T-cell link of immunity. Ascorbic acid activates the humoral link of immunity,normalizes capillary permeability, thereby reducing inflammation, and exhibits antioxidant properties, neutralizing oxygen radicals accompanying the inflammatory process, increases the body's resistance to infection.

Pharmacokinetics

Absorption and distribution When taken orally, the drug is completely absorbed from the gastrointestinal tract. Bioavailability of bendazole is about 80%, alpha-glutamyl-tryptophan is no more than 15%, ascorbic acid is up to 70%. Ascorbic acid is absorbed from the gastrointestinal tract (mainly in the jejunum). Plasma protein binding - 25%. Tmax after oral administration - 4 hours. It easily penetrates into leukocytes, platelets, and then into all tissues, penetrates the placental barrier. Diseases of the gastrointestinal tract (peptic ulcer and duodenal ulcer, intestinal motility disorders, helminthic invasion, giardiasis), the use of fresh vegetable and fruit juices, alkaline drinks reduce the binding of ascorbic acid in the intestine. Metabolism and excretion Ascorbic acid is metabolized mainly in the liver with the formation of deoxyascorbic, then oxaloacetic and diketogulonic acids.It is excreted by the kidneys, through the intestines, with sweat, breast milk unchanged and in the form of metabolites. Biotransformation products of bendazole in the blood are two conjugates formed as a result of methylation and carboethoxylation of the imino group of the imidazole ring of bendazole: 1-methyl-2-benzylbenzimidazole and 1-carboethoxy-2-benzylbenzimidazole. Bendazole metabolites are excreted in the urine. Alpha-glutamyl-tryptophan is cleaved by peptidases into L-glutamic acid and L-tryptophan, which are used by the body in protein synthesis.1-methyl-2-benzylbenzimidazole and 1-carboethoxy-2-benzylbenzimidazole. Bendazole metabolites are excreted in the urine. Alpha-glutamyl-tryptophan is cleaved by peptidases into L-glutamic acid and L-tryptophan, which are used by the body in protein synthesis.1-methyl-2-benzylbenzimidazole and 1-carboethoxy-2-benzylbenzimidazole. Bendazole metabolites are excreted in the urine. Alpha-glutamyl-tryptophan is cleaved by peptidases into L-glutamic acid and L-tryptophan, which are used by the body in protein synthesis.

Indications for use

- prevention and complex therapy of influenza and ARVI in children from 1 year old.

Contraindications for use

- hypersensitivity to drug components

- diabetes

- pregnancy

- children under 1 year old.

If necessary, the patient should consult a doctor before taking the drug.

With caution: in case of arterial hypertension, the patient should consult a doctor before taking the drug.

Dosage regimen

The therapeutic and prophylactic regimens are identical.

The drug is taken orally 30 minutes before meals.

Children aged 1 to 3 years - 2 ml 3 times / day.

Children aged 3 to 6 years - 4 ml 3 times / day.

Children aged 6 to

Name ENG

CYTOVIR-3

Clinical and pharmacological group

Immunostimulating drug

ATX code

Other immunostimulants

Dosage

0.15mg / ml + 12mg / ml + 1.25mg / ml x 50ml

Structure

1 ml contains ascorbic acid 12 mg, bendazole 1.25 mg, sodium thymogen 150 mcg

excipients: sucrose, purified water

INN / Active ingredient

bendazole hydrochloride, ascorbic acid, alpha-glutamyl-tryptophan sodium (sodium thymogen)

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 2 years

Specifications

Category

Antiviral

,

Antimicrobial agents

Scope of the medicinal product

Ear, Throat, Nose

Release form

Syrup

Manufacturer country

Russia

Package quantity, pcs

one

Minimum age from

1 year

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Cytomed

Components

dosage spoon

The amount of the dosage form in the primary package

50 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Immunostimulating agent

Anatomical and therapeutic characteristics

L03AX Other immunostimulants

Dosage form

Syrup [for children]

The target audience

Children

Expiration date in days

730

Package weight, g

150

Mode of application

:

Cytovir-3 is taken orally, orally 30 minutes before meals, 3 times a day for 4 days.

Schemes of admission for the purpose of prevention and treatment are identical. < br> Children aged 1 to 3 years are prescribed 2 ml of syrup

children aged 3 to 6 years - 4 ml of syrup, children from 6 to 10 years old - 8 ml, children over 10 years old - 12 ml 3 times a day for 4 days. < br> < br> With preventive the purpose of a second course of treatment can be carried out in 3-4 weeks.

Dosage (volume) of the substance in the preparation

:

alpha-glutamyl-tryptophan sodium (in terms of alpha-glutamyl-tryptophan) 0.15 mg, ascorbic acid 12 mg, bendazole hydrochloride 1.25 mg

Information on technical characteristics, delivery set, country of manufacture