Tryptorelyn | Dekapeptil solution for p / dermal introduced. 0.1 mg / ml 1 ml syringe with a needle 7 pcs.

Latin name

DECAPEPTYL

Release form

Injection.

Packing

7 pcs

Indications

For women: endometriosis

uterine fibroids

infertility treatment using assisted reproductive technologies (including IVF and PE / embryo transfer /).

For men: symptomatic treatment of progressive hormone-dependent prostate carcinoma.

Contraindications

For women

pregnancy

lactation period

clinical manifestations or risk of osteoporosis.

With caution: use the drug in an assisted reproductive technology (IVF) program in patients with polycystic ovary, when the number of follicles determined by ultrasound is more than 10.

For men,

is a hormone-independent prostate carcinoma

prior surgical castration.

General

hypersensitivity to triptorelin or other components of the drug.

Use during pregnancy and lactation

The use of the drug during pregnancy and during breast-feeding is contraindicated.

Composition

1 ml contains:

Active substances: tryptorelin acetate 105 μg, which corresponds to the content of tryptorelin 95.6 μg.

Excipients: sodium chloride, glacial acetic acid, water d / and.

Dosage and administration of

The drug is administered sc.

IVF treatment of women with IVF

Usually administered at a dose of 0.1 mg per day of the menstrual cycle or early follicular phase until the introduction of chorionic gonadotropin (hCG) (short protocol) or from day 1 of the menstrual cycle or early follicular phase for 3 days (ultra-short protocol).

Uterine fibroids, endometriosis, prostate carcinoma

At the beginning of the course of treatment for 1 day, 1 ml of the drug Decapeptil 0.5 mg (1 injection) is administered subcutaneously 1 time / day. Starting from the 8th day of treatment, Decapeptil 0.1 mg should be administered daily to maintain a therapeutic effect. The injection site should be changed.

For a long course of treatment, it is recommended to use the drug Decapeptil-Depot (3.75 mg of triptorelin in microcapsules of slow release) - 1 injection every 28 days.

Side effects

Side effects are caused by a decrease in the level of sex hormones in the blood, which can lead to the appearance in men and women of symptoms such as lability of mood, depression, weakening libido, frequent headaches, sleep disturbances, weight gain, hot flashes, increased sweating.

From the genitourinary system: obstruction of the urinary tract, pain during intercourse. In women - vaginal dryness, uterine bleeding. In men - a decrease in potency, gynecomastia, a decrease in the size of the testicles.

From the side of the central nervous system and peripheral nervous system: paresthesia, visual impairment.

From the digestive system: nausea, decreased appetite, increased activity of hepatic transaminases, hypercholesterolemia.

From the musculoskeletal system: back pain, bone pain, caused by metastases, spinal cord compression, muscle weakness, myalgia, arthralgia, demineralization of bones (with prolonged use).

Allergic reactions: itching, redness of the skin, fever, anaphylaxis.

Local reactions: rarely - pain at the injection site.

Other: thrombophlebitis, swollen lymph nodes, leg swelling, in men - a decrease in beard growth and loss of hair on the chest, arms and legs.

All described adverse reactions disappear after the end of the course of treatment.

Drug Interaction

Interaction of Decapeptil with other drugs has not been established.

Overdose

No drug overdose was observed. If overdose occurs, symptomatic treatment should be performed.

Storage conditions

Keep out of the reach of children, protected from light (in unopened packaging) at a temperature of 2 ° to 8 РC.

The Expiration of

is 3 years.

Deystvuyuschee substances

Tryptorelyn

Pharmacy terms of sale

Prescription

dosage form

dosage form

injection