Trimetin powder 500g

DESCRIPTION

Trimetin (Trimetin) - powder for oral administration for the treatment of farm animals, dogs and cats in diseases of bacterial etiology.

ADVANTAGES

Complex antibacterial drug with a wide spectrum of activity

Synergistic action of the components

50% more profitable than imported analogues

COMPOSITION

1 g of powder contains as active ingredients: sulfamethoxazole 0.1 g, trimethoprim - 0.02 g and an auxiliary substance - lactose - up to 1 g.

PHARMACOLOGICAL PROPERTIES

Pharmacotherapeutic group of the drug: sulfonamides. The mechanism of action is due to the double blocking effect on the metabolism of gram-positive and gram-negative microorganisms that cause infectious diseases in animals.

Sulfamethoxazole, which is structurally similar to para-aminobenzoic acid (PABA), is captured by the microbial cell and prevents the incorporation of PABA into the dihydrofolic acid molecule.

Trimethoprim reversibly inhibits bacterial dihydrofolate reductase, disrupts the synthesis of tetrahydrofolic acid from dihydrofolic acid, the formation of purine and pyrimidine bases, nucleic acids; inhibits the growth and reproduction of microorganisms. After oral administration, both components are rapidly and almost completely absorbed in the gastrointestinal tract.

The maximum antibacterial concentration in the blood is observed 3-4 hours after taking the drug and is maintained at a therapeutic level for 12 hours. Sulfamethoxazole and trimethoprim are excreted mainly in the urine. According to the degree of impact on the body, the drug is classified as a moderately hazardous substance (hazard class 3 according to GOST 12.1.007).

DOSAGE AND APPLICATION

Trimetin is used in calves, foals, lambs and pigs, dogs and cats for diseases of the genitourinary system, respiratory system, gastrointestinal tract, salmonellosis, colibacillosis, as well as for other diseases, the causative agents of which are sensitive to sulfamethoxazole.

The drug is used individually or in a group way to calves, foals, lambs and pigs, cats and dogs mixed with food or individually in the form of a suspension by dissolving the powder in a small amount of water (milk) 2 times a day at a dose of 250 mg per 1 kg of animal weight , until the clinical signs of the disease disappear and within the next two days, but not more than 10 days. During treatment, animals are provided with free access to water.

SPECIAL INSTRUCTIONS

The peculiarities of the action of the drug during its first use and withdrawal have not been established.

Avoid skipping the next dose of the drug, as this can lead to a decrease in therapeutic effectiveness. If one dose is missed, the use of the drug is resumed in the same dosage and according to the same scheme.

With increased individual sensitivity of animals to sulfonamides and trimethoprim, loss of appetite, diarrhea and vomiting are possible. The use of the drug in these cases is stopped immediately.

Interaction with other medicinal products has not been established.

Slaughter of animals for meat is allowed no earlier than 7 days after the last use of Trimetin. In case of forced slaughter earlier than the established deadline, the meat can be used as feed for carnivores.

CONTRAINDICATIONS

Contraindications for the use of Trimetin are diseases of the hematopoietic organs, optic nerve, acute hepatitis, nephritis, B12-deficiency anemia, and hypersensitivity to sulfanilamide drugs. It is forbidden to use Trimetin in animals with developed cicatricial digestion.

SIDE EFFECTS

Overdose symptoms: anorexia, nausea, vomiting, weakness, colic, drowsiness. The use of Trimetin in these cases is stopped. The animal needs to undergo a gastric lavage and provide an abundant drink.

SHELF LIFE AND STORAGE

Store Trimetin in sealed manufacturer's packaging in a dry place protected from direct light, separately from food and feed, at a temperature from minus 20 В° C to 20 В° C.

The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of manufacture. It is prohibited to use the medicinal product after the expiration date.

PACKAGING

The drug is produced in 0.5 kg cans in polypropylene cans with a sealing element made of high-pressure polyethylene, in which bags made of polyethylene film are previously inserted, hermetically sealed or in polyethylene bags, hermetically sealed. Each packing unit is supplied with instructions for use.

Specifications

KolVUP

12

Manufacturer

Askont +

Temperature regime

from -20 to +25

Teaser

for the treatment of farm animals, dogs and cats in diseases of bacterial etiology