trimethazidine | Antisten MV tablets 35 mg, 60 pcs.
Special Price
$23.28
Regular Price
$31.00
In stock
SKU
BID470198
Latin name
Antisten MB
Antisten MB
Latin name
Antisten MB
Release form
Coated tablets.
Packing
10 pcs - blister packagings (6) - cardboard boxes.
Pharmacological action
An agent that normalizes the energy metabolism of cells undergoing hypoxia or ischemia. Prevents a decrease in the intracellular ATP content, ensures the normal functioning of membrane ion channels, transmembrane transfer of potassium and sodium ions and preservation of cell homeostasis.
Trimetazidine inhibits fatty acid oxidation by selectively inhibiting long-chain 3-ketoacetyl-CoA thiolase, which leads to increased glucose oxidation and to the restoration of conjugation between glycolysis and oxidative decarboxylation and, as shown, protects the myocardium from ischemia. Switching fatty acid oxidation to glucose oxidation underlies the antianginal action of trimetazidine.
In experimental animal studies, trimetazidine supports the energy metabolism of the heart and neurosensory organs during periods of ischemic episodes, reduces the magnitude of intracellular acidosis and the degree of change in the transmembrane ion flux resulting from ischemia reduces the level of migration and infiltration of polynuclear neutrophils in ischemic and reperfusion tissues reduces the size of myocardial damage while it does not affect hemodynamics.
Indications
Long-term therapy for coronary heart disease: prevention of angina attacks (monotherapy or as part of combination therapy) treatment of cochleo-vestibular disorders of ischemic nature (including dizziness, tinnitus, hearing impairment) chorioretinal vascular disorders with ischemic component.
Contraindications
Pregnancy, lactation (breastfeeding), hypersensitivity to trimetazidine.
Use during pregnancy and lactation
Trimetazidine is contraindicated in pregnancy and lactation (breastfeeding).
Dosage and administration
Take orally at a dose of 40-60 mg / day, frequency of administration 2-3 times / day. The duration of therapy is set individually, depending on the clinical situation.
Side effects
Possible: allergic reactions (including skin rash, itching).
Rarely: nausea, vomiting, gastralgia.
Overdose
No overdose has been reported at this time.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 РC. Protect from moisture.
Keep out of the reach and sight of children.
Shelf life
3 years.
Do not use after the expiration date printed on the package.
Deystvuyushtee substance
trimetazidine
Terms and conditions
prescription
Dosage PMA
Prescribing
Prescribing
For adults as prescribed by a doctor
Antisten MB
Release form
Coated tablets.
Packing
10 pcs - blister packagings (6) - cardboard boxes.
Pharmacological action
An agent that normalizes the energy metabolism of cells undergoing hypoxia or ischemia. Prevents a decrease in the intracellular ATP content, ensures the normal functioning of membrane ion channels, transmembrane transfer of potassium and sodium ions and preservation of cell homeostasis.
Trimetazidine inhibits fatty acid oxidation by selectively inhibiting long-chain 3-ketoacetyl-CoA thiolase, which leads to increased glucose oxidation and to the restoration of conjugation between glycolysis and oxidative decarboxylation and, as shown, protects the myocardium from ischemia. Switching fatty acid oxidation to glucose oxidation underlies the antianginal action of trimetazidine.
In experimental animal studies, trimetazidine supports the energy metabolism of the heart and neurosensory organs during periods of ischemic episodes, reduces the magnitude of intracellular acidosis and the degree of change in the transmembrane ion flux resulting from ischemia reduces the level of migration and infiltration of polynuclear neutrophils in ischemic and reperfusion tissues reduces the size of myocardial damage while it does not affect hemodynamics.
Indications
Long-term therapy for coronary heart disease: prevention of angina attacks (monotherapy or as part of combination therapy) treatment of cochleo-vestibular disorders of ischemic nature (including dizziness, tinnitus, hearing impairment) chorioretinal vascular disorders with ischemic component.
Contraindications
Pregnancy, lactation (breastfeeding), hypersensitivity to trimetazidine.
Use during pregnancy and lactation
Trimetazidine is contraindicated in pregnancy and lactation (breastfeeding).
Dosage and administration
Take orally at a dose of 40-60 mg / day, frequency of administration 2-3 times / day. The duration of therapy is set individually, depending on the clinical situation.
Side effects
Possible: allergic reactions (including skin rash, itching).
Rarely: nausea, vomiting, gastralgia.
Overdose
No overdose has been reported at this time.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 РC. Protect from moisture.
Keep out of the reach and sight of children.
Shelf life
3 years.
Do not use after the expiration date printed on the package.
Deystvuyushtee substance
trimetazidine
Terms and conditions
prescription
Dosage PMA
Prescribing
Prescribing
For adults as prescribed by a doctor
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