Trimetazidine MV tablets p / o 35mg, No. 30

- Ischemic heart disease: prevention of angina attacks (in complex therapy): -
Chorioretinal vascular disorders -
Dizziness of vascular origin -
Cochleo-vestibular disorders of an ischemic nature (tinnitus, hearing impairment).

Inside, during meals.
The recommended dosage regimen is 20 mg (40-60 mg) per day, in 2-3 doses.
The course of treatment is according to the doctor's recommendation.

Active ingredient: trimetazidine dihydrochloride - 35 mg;

Excipients (core): hypromellose - 93.0 mg, cellulose

microcrystalline - 178.9 mg, colloidal silicon dioxide - 1.55 mg, magnesium stearate - 1.55 mg.

Excipients (shell): opadry II 85F240012 pink - 10.0 mg, incl. polyvinyl alcohol - 4.0 mg, macrogol-3350 - 2.438 mg, iron dye red oxide - 0.04 mg, iron dye yellow oxide - 0.022 mg, talc - 1.48 mg, titanium dioxide 2.02 mg

- Hypersensitivity to any component of the drug Trimetazidine;
- Renal failure (creatinine clearance below 15 ml / min);
- Severe liver dysfunction;
- Pregnancy;
- Breastfeeding period:
- Age up to 18 years (efficacy and safety have not been established).

Pharmacological action
Trimetazidine has an antihypoxic effect.

Indications
- Ischemic heart disease: prevention of angina attacks (in complex therapy): -
Chorioretinal vascular disorders -
Dizziness of vascular origin -
Cochleo-vestibular disorders of an ischemic nature (tinnitus, hearing impairment).

Contraindications
- Hypersensitivity to any component of the drug Trimetazidine;
- Renal failure (creatinine clearance below 15 ml / min);
- Severe liver dysfunction;
- Pregnancy;
- Breastfeeding period:
- Age up to 18 years (efficacy and safety have not been established).

Method of administration and dosage
Inside, during meals.
The recommended dosage regimen is 20 mg (40-60 mg) per day, in 2-3 doses.
The course of treatment is according to the doctor's recommendation.

Side effects
From the digestive system:
Often: abdominal pain, diarrhea, dyspepsia, nausea, vomiting.
General disorders:
Often: asthenia.
From the side of the central nervous system:
Often: dizziness, headache.
Very rare: extrapyramidal disorders (tremor, rigidity, akinesia), reversible after drug withdrawal.
On the part of the skin:
Often: skin rash, itching, urticaria.
From the side of the cardiovascular system:
Rarely: orthostatic hypotension, 'hot flushes' of blood to the skin of the face.