Triderm ointment for external use 15 g

Release form, composition and packaging

Ointment for external use from white to light yellow, soft consistency, homogeneous, translucent, free of impurities.

1 g

betamethasone dipropionate 643 mcg, which corresponds to the content of betamethasone 500 mcg

clotrimazole

10 mg

gentamicin (as sulfate)

1 mg (1000 ME)

liquid paraffin - 50 mg, soft white paraffin - qs up to 1 g.

15 g - aluminum tubes (1) - cardboard packs.

30 g - aluminum tubes (1) - cardboard packs.

pharmachologic effect

Combined preparation for external use.

Triderm combines the anti-inflammatory, antipruritic, antiallergic and antiexudative effect of betamethasone dipropionate GCS with the antifungal activity of clotrimazole and the broad antibacterial effect of gentamicin sulfate.

Clotrimazole has an antifungal effect by disrupting the synthesis of ergosterol, which is an integral part of the fungal cell membrane.

Active against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furfur (Pityrosporum orbiculare).

Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group.

Acts bactericidal and provides highly effective local treatment of primary and secondary bacterial skin infections.

Active against gram-negative bacteria: Pseudomonas aeruginosa, Enterobacter aerogenes, Escherichia coli, Proteus vulgaris and Klebsiella pneumoniae

gram-positive bacteria: Staphylococcus aureus (coagulase-positive, coagulase-negative and some strains that produce penicillinase).

Pharmacokinetics

Data on the pharmacokinetics of Triderm are not provided.

Indications for use

Dermatoses complicated by infections caused by pathogens sensitive to the drug, or with suspicion of such infections, including:

- simple and allergic dermatitis

- atopic dermatitis (including diffuse neurodermatitis)

- limited neurodermatitis

- eczema

- dermatomycosis (dermatophytosis, candidiasis, versicolor versicolor), especially when localized in the groin and large folds of the skin.

Lichen simplex chronicus (limited neurodermatitis).

Contraindications for use

- tuberculosis of the skin

- cutaneous manifestations of syphilis

- chickenpox

- herpes simplex

- post-vaccination skin reactions

- open wounds (for ointment)

- children under 2 years old

- hypersensitivity to drug components.

The drug should be used with caution during pregnancy (especially in the first trimester), in children over the age of 2 years, for long-term treatment, on large areas of the skin or in violation of the integrity of the skin, when using occlusive dressings (especially in children).

Dosage regimen

The drug is intended for external use.

Triderm should be applied in a thin layer to the entire affected skin surface and surrounding tissue 2 times / day - in the morning and at night.

To ensure the effectiveness of treatment, Triderm must be used regularly.

The duration of therapy depends on the size and location of the lesion, as well as on the patient's response.

If clinical improvement does not occur after 3-4 weeks of treatment, this may serve as a reason for clarifying the diagnosis.

Overdose

Symptoms

With long-term use of local GCS in high doses, it is possible to suppress the function of the adrenal glands with the development of secondary adrenal insufficiency and symptoms of hypercortisolism, including Cushing's syndrome.

An overdose of clotrimazole when applied topically does not lead to the appearance of any symptoms.

With a single overdose of gentamicin, no symptoms are expected either.

Long-term treatment with gentamicin in high doses can lead to the growth of insensitive flora.

Treatment

Conducting symptomatic therapy.

Sharp

Name ENG

TRIDERM

Clinical and pharmacological group

Drug with antibacterial, antifungal and anti-inflammatory action for external use

ATX code

Betamethasone in combination with other drugs

Dosage

0.5mg / g + 1mg / g + 10mg / g x 15g

Structure

1 g of ointment contains: betamethasone 0.5 mg, clotrimazole 10 mg, gentamicin 1 mg.

Excipients: liquid paraffin (50 mg), white petrolatum (qs ad 1000).

Indications

Dermatoses complicated by infections caused by pathogens sensitive to the drug, or with suspicion of such infections, including:

simple and allergic dermatitis

atopic dermatitis (including diffuse neurodermatitis)

limited neurodermatitis

eczema

dermatomycosis (dermatophytosis, candidiasis, versicolor versicolor), especially when localized in the groin and large folds of the skin.

Lichen simplex chronicus (limited neurodermatitis).

Contraindications

lupus

cutaneous manifestations of syphilis

chickenpox

herpes simplex

post-vaccination skin reactions

open wounds (for ointment)

children under 2 years of age

hypersensitivity to drug components.

The drug should be used with caution during pregnancy (especially in the first trimester), in children over the age of 2 years, for long-term treatment, on large areas of the skin or in violation of the integrity of the skin, when using occlusive dressings (especially in children).

INN / Active ingredient

Betamethasone + Gentamicin + Clotrimazole

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 2 years

Specifications

Category

Psoriasis

Scope of the medicinal product

Dermatology

Release form

Ointment

Manufacturer country

Belgium

Package quantity, pcs

one

Way of introduction

On the skin

Vacation conditions

Without recipe

Brand name

Triderm

The amount of the dosage form in the primary package

15 g

Primary packaging type

Aluminum tube

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

D07XC01 Betamethasone, in combination with other drugs

Dosage form

Ointment for external use

Expiration date in days

730

Dosage (volume) of the substance in the preparation

0.5 mg, 10 mg, 1 mg

Package weight, g

thirty

Mode of application

:

Triderm ointment should be applied in a thin layer to the entire affected skin surface and surrounding tissue twice a day - in the morning and at night.

To ensure the effectiveness of treatment, Triderm ointment must be applied regularly.

The duration of therapy depends on the size and location of the lesion, as well as the patient's response.

If clinical improvement does not occur after 3-4 weeks of baking, this may serve as a reason for clarifying the diagnosis.

Pharmaco-therapeutic group

:

Anti-inflammatory, antibacterial, antifungal agent

Information on technical characteristics, delivery set, country of manufacture