Triderm Cream For External Use 15 g

Structure

1 g of cream contains: betamethasone 0.5 mg, clotrimazole 10 mg, gentamicin 1 mg.

Excipients: liquid paraffin, white petrolatum I, cetostearyl alcohol, propylene glycol, cetomacrogol-1000.

gasoline alcohol, J sodium dibasic phosphate dihydrate, phosphoric acid, sodium hydroxide (to establish the required pH value), purified water (qs ad 1000 mg).

pharmachologic effect

Pharmaceutical group: glucocorticosteroid + antibiotic-aminoglycoside + antifungal agent.

Pharmaceutical action: Triderm is a combined preparation.

Triderm® ointment and cream combine the anti-inflammatory, antipruritic, anti-allergic and anti-exudative effect of betamethasone dipropionate with the antifungal activity of clotrimazole and the broad antibacterial effect of gentamicin sulfate.

Clotrimazole has an antifungal effect (inhibits the synthesis of ergosterol in the cell membrane of fungi). Active against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furfur (Pityrosporum orbiculare).

Gentamicin sulfate, a broad-spectrum aminoglycoside antibiotic, is bactericidal and provides highly effective topical treatment of primary and secondary bacterial skin infections.

Active against gram-negative microorganisms: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae

gram-positive microorganisms: Streptococcus spp.

(sensitive strains of alpha and beta hemolytic group A streptococcus), Staphylococcus aureus (coagulase-positive, coagulase-negative, and some strains producing penicillinase).

Indications

- reduction of inflammatory manifestations of dermatoses, complicated by primary and secondary infections (simple and allergic dermatitis, atopic dermatitis, diffuse neurodermatitis, limited neurodermatitis)

- athlete's foot

- pityriasis versicolor

- simple chronic lichen

- dermatomycosis (including inguinal and in large folds of the skin), caused by pathogens sensitive to the drug: dermatophytosis, candidiasis

versicolor versicolor.

Application during pregnancy and lactation

The use of TRIDERM during pregnancy is possible only if the intended benefit to the mother outweighs the potential risk to the fetus.

It is not known whether the components of the drug are excreted in breast milk.

Therefore, when prescribing TRIDERM during lactation, the issue of stopping breastfeeding should be resolved.

Contraindications

- hypersensitivity to any of the components of the drug Triderm

- tuberculosis of the skin

- cutaneous manifestations of syphilis

- chickenpox

- herpes simplex

- post-vaccination skin reactions

- age up to 2 years.

Side effects

Local reactions: burning sensation, erythema, exudation, pigmentation disorders, itching.

Adverse reactions caused by betamethasone: burning sensation, itching, irritation and dryness of the skin, folliculitis, hypertrichosis, acne-like rashes, hypopigmentation, perioral dermatitis, skin maceration, secondary infection, skin atrophy, striae, prickly heat.

Adverse reactions due to clotrimazole: erythema, scaling, local edema, itching, urticaria, skin maceration, paresthesia.

Adverse reactions due to gentamicin: hyperemia, itching.

How to take, course of administration and dosage

The cream is used in the treatment of acute weeping skin lesions - in processes with weeping and severe inflammation.

TRIDERM cream should be applied in a thin layer to the entire affected skin surface and surrounding tissue twice a day - in the morning and at night.

To ensure the effectiveness of treatment, TRIDERM cream must be used regularly.

The duration of therapy depends on the size and location of the lesion, as well as the patient's response.

If clinical improvement does not occur after 3-4 weeks of treatment, this may be a reason for

Name ENG

TRIDERM

Clinical and pharmacological group

Drug with antibacterial, antifungal and anti-inflammatory action for external use

ATX code

Betamethasone in combination with other drugs

Dosage

0.05% + 0.1% + 1% x 15g

Structure

1 g of cream contains: betamethasone 0.5 mg, clotrimazole 10 mg, gentamicin 1 mg.

Excipients: liquid paraffin, white petrolatum I, cetostearyl alcohol, propylene glycol, cetomacrogol-1000.

gasoline alcohol, J sodium dibasic phosphate dihydrate, phosphoric acid, sodium hydroxide (to establish the required pH value), purified water (qs ad 1000 mg).

Indications

Triderm cream is indicated for the reduction of inflammatory manifestations of skin diseases: dermatoses complicated by primary and secondary infection

athlete's foot

pityriasis lichen

dermatomycosis (including inguinal) caused by pathogens sensitive to the drug.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

INN / Active ingredient

Betamethasone + Gentamicin + Clotrimazole

Contraindications

Hypersensitivity to drug components

Specifications

Category

Psoriasis

Scope of the drug

Dermatology

Release form

Cream

Manufacturer country

Belgium

Package quantity, pcs

one

Way of introduction

On the skin

Vacation conditions

Without recipe

Brand name

Triderm

The amount of the dosage form in the primary package

15 g

Primary packaging type

Aluminum tube

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

D07XC01 Betamethasone, in combination with other drugs

Dosage form

Cream for external use

Item weight, g

15

The target audience

Children

Expiration date in days

1095

Package weight, g

twenty

Mode of application

:

The cream is used in the treatment of acute weeping skin lesions - in processes with weeping and severe inflammation.

TRIDERM cream should be applied in a thin layer to the entire affected skin surface and surrounding tissue twice a day - in the morning and at night.

To ensure the effectiveness of treatment, TRIDERM cream must be used regularly.

The duration of therapy depends on the size and location of the lesion, as well as the patient's response.

If clinical improvement does not occur after 3-4 weeks of treatment, this may serve as a reason for clarifying the diagnosis.

Pharmaco-therapeutic group

:

Anti-inflammatory, antibacterial, antifungal agent

Dosage (volume) of the substance in the preparation

:

betamethasone dipropionate 643 mcg, which corresponds to the content of betamethasone 500 mcg, clotrimazole 10 mg, gentamicin (in the form of sulfate) 1 mg (1000 IU)

Information on technical characteristics, delivery set, country of manufacture