Torendo Ku-tab tablets 0.5mg, No. 30

schizophrenia (acute and chronic) and other psychotic conditions with productive and / or negative symptoms;

affective disorders in various mental illnesses;

behavioral disorders in patients with dementia with the manifestation of symptoms of aggressiveness (outbursts of anger, physical violence), with mental disorders (agitation, delirium) or psychotic symptoms;

as an adjunct therapy in the treatment of manias in bipolar disorders;

as an adjunct therapy for behavioral disorders in adolescents from 15 years of age and adult patients with a reduced intellectual level or mental retardation in cases where destructive behavior (aggressiveness, impulsivity, autoaggression) is leading in the clinical picture of the disease.

Sublingual. Lozenges are fragile, they should not be squeezed through the foil of the packaging, because they can break. Open the package by gently pulling on the edge of the blister foil marked with a dot, remove the tablet and immediately put it on the tongue. The tablet begins to dissolve in the mouth within a few seconds and can be swallowed without water; you should also not mix the drug in the mouth with food, bite or chew.

Schizophrenia (acute and chronic) and other psychotic conditions with productive and / or negative symptoms. For adults and children over 15 years of age, the drug is prescribed 1 or 2 times a day. The initial dose is 2 mg / day. On the second day, the dose should be increased to 4 mg / day. From this point on, the dose can either be kept at the same level or individually adjusted if necessary. Usually the optimal dose is 4-6 mg / day. In some cases, a slower dose increase and lower initial and maintenance doses may be justified.

Doses above 10 mg / day do not show higher efficacy compared to lower doses and may cause extrapyramidal symptoms. Due to the fact that the safety of doses above 16 mg / day has not been studied, doses above this level should not be used.

Behavioral disorders in patients with dementia with symptoms of aggressiveness (outbursts of anger, physical violence). Mental disorders (agitation, delusions) or psychotic symptoms. The recommended initial dose is 0.25 mg 2 times a day (an adequate dosage form should be used). The dosage, if necessary, can be individually increased by 0.25 mg 2 times a day, not more often than every other day. For most patients, the optimal dose is 0.5 mg 2 times a day. However, some patients are shown taking 1 mg 2 times a day. Upon reaching the optimal dose, it may be recommended to take the drug once a day.

Mania in bipolar disorder. The recommended starting dose is 2 mg once a day. If necessary, this dose can be increased by 2 mg / day no more often than every other day. For most patients, the optimal dose is 2Ц6 mg / day.

Behavioral disorders in adolescents from 15 years of age and adult patients with a reduced intellectual level or mental retardation. Patients weighing 50 kg or more. The recommended starting dose is 0.5 mg once a day. If necessary, this dose can be increased by 0.5 mg / day, not more often than every other day. For most patients, the optimal dose is 1 mg / day. However, for some patients, a dose of 0.5 mg / day is preferable, while some require an increase in the dose to 1.5 mg / day.

Special patient groups

Elderly patients. The initial dose is 0.5 mg 2 times a day. The dosage can be individually increased by 0.5 mg 2 times a day to 1-2 mg 2 times a day.

Children. The use of TorendoЃ Ku-tab in children under 15 years of age is contraindicated.

Long-term use of TorendoЃ Ku-tab in adolescents over 15 years old requires constant medical supervision.

Impaired renal and / or liver function. It is recommended to start therapy with TorendoЃ Ku-tab with 0.5 mg 2 times a day. The dose can be gradually increased by 0.5 mg of risperidone 2 times a day to 1-2 mg / day. In this group of patients, the drug TorendoЃ Ku-tab should be used with caution until more complete information is obtained.

Drug abuse or drug dependence. The recommended daily dose of the drug is 2-4 mg.

Patients weighing less than 50 kg. The recommended initial dose of the drug is 0.25 mg once a day. If necessary, this dose can be increased by 0.25 mg / day, not more often than every other day. For most patients, the optimal dose is 0.5 mg / day. However, for some patients, a dose of 0.25 mg / day is preferable, while others require an increase in dose to 0.75 mg / day.

hypersensitivity to drug components;

mania in bipolar affective disorders in children under the age of 18 (efficacy and safety have not been established);

schizophrenia (acute and chronic) and other psychotic conditions with productive and / or negative symptoms in children under 15;

affective disorders in various mental illnesses in children under 15 years of age;

period of breastfeeding.

With care: pregnancy; CVS diseases (chronic heart failure, myocardial infarction, cardiac muscle conduction disorders); dehydration and hypovolemia; cerebral circulation disorders; Parkinson's disease; convulsions (including history); severe renal and / or hepatic impairment; drug abuse or drug dependence; conditions predisposing to the development of tachycardia of the 'pirouette' type (bradycardia, electrolyte imbalance, simultaneous use of drugs that lengthen the QT interval); brain tumor, intestinal obstruction, cases of acute drug overdose, Reye's syndrome (the antiemetic effect of risperidone can mask the symptoms of these conditions); old age with dementia; use in combination with furosemide; thrombophlebitis; hyperglycemia.