Tiercal 100ml

DESCRIPTION

Tierkal is an antibacterial drug in the form of a suspension for injection. In appearance, it is a light yellow oily liquid.

COMPOSITION

Contains 50 mg of ceftiofur hydrochloride and auxiliary components in 1 ml as an active ingredient.

PHARMACOLOGICAL PROPERTIES

Tierkal is an antibiotic of the third-generation cephalosporin group, has a wide spectrum of antibacterial action, is active against gram-positive and gram-negative microorganisms, including Streptococcus spp., Actinomyces pyogenes, Staphylococcus spp., Salmonella choleraesuis, Escherureichia haemolyus, , Actinobacillus pleuropneumoniae, Haemophilus parasuis, Klebsiella spp., Citrobacter spp., Enterobacter spp., Bacillus spp., Proteus spp., Fusobacterium necrophorum and Bacteroides melaninogenicus, including lactamase-producing strains. The mechanism of action of ceftiofur, which is part of tierkal, is to suppress the synthesis of the bacterial cell wall. After administration, ceftiofur is rapidly metabolized to form desfuroylceftiofur, which has an activity equivalent to ceftiofur against bacteria. The active metabolite binds reversibly to blood plasma proteins and concentrates in the tissues affected by the pathogen. The maximum concentration of ceftiofur and its metabolites in the blood is reached after 0.5 - 2 hours and is maintained at a therapeutic level for up to 24 hours from the moment of drug administration, while the activity of the drug does not decrease in the presence of necrotic tissues. Ceftiofur and its metabolites are excreted from the body of the animal mainly in the urine. 5 - 2 hours and is kept at a therapeutic level for up to 24 hours from the moment of drug administration, while the activity of the drug does not decrease in the presence of necrotic tissues. Ceftiofur and its metabolites are excreted from the animal body mainly in the urine. 5 - 2 hours and is kept at a therapeutic level for up to 24 hours from the moment of drug administration, while the activity of the drug does not decrease in the presence of necrotic tissues. Ceftiofur and its metabolites are excreted from the body of the animal mainly in the urine.

INDICATIONS

Prescribed to cattle for the treatment of necrobacteriosis associated with Fusobacterium necrophorum and Bacteroides melaninogenicus, acute postpartum endometritis, bacterial infections of the respiratory tract caused by Pasteurella haemolytica, Pasteurella multocida and Haemophilus somnus. Pigs for the treatment of bacterial infections of the respiratory tract caused by Pasteurella haemolytica, Actinobacillus pleuropneumoniae and Streptococcus suis.

DOSAGE AND APPLICATION

Tierkal is administered to cattle subcutaneously at the rate of 1 ml of the drug per 50 kg of animal weight, which corresponds to 1 mg of ceftiofur per 1 kg of animal weight, with necrobacteriosis within 3 days, with endometritis within 5 days (in the first 10 days after calving), for diseases of the respiratory tract within 3 - 5 days. Pigs - intramuscularly at the rate of 1 ml of the drug per 16 kg of animal weight, which corresponds to 3 mg of ceftiofur per 1 kg of animal weight, for 3 days. Before each use, shake the bottle with Thierkal thoroughly until a homogeneous suspension is obtained.

SIDE EFFECTS

With proper use and dosage, side effects are usually not observed.

CONTRAINDICATIONS

Increased individual sensitivity to cephalosporin antibiotics. In case of allergic reactions, the drug should be discontinued and antihistamines should be prescribed. Tierkal should not be mixed with other drugs in the same syringe.

FEATURES

Slaughter of cattle for meat is allowed after 8 days, and pigs - 5 days after the last use of tierkal. In the event of the forced slaughter of animals before the established deadline, meat is used to feed carnivores or for the production of meat and bone meal. Milk from cattle can be used for food purposes without restrictions.

SHELF LIFE AND STORAGE

With precautions according to list B. In a dry, dark place and out of reach of children and animals at a temperature of 5 to 25? C. Shelf life - 2 years, after opening the bottle - no more than 24 days.

PACKAGING

Packaged in 100 ml bottles made of dark glass, which are packed in cardboard boxes.

Specifications

KolVUP

ten

Manufacturer

Livisto

Temperature regime

from +5 to +25

Teaser

appoint cattle for the treatment of necrobacteriosis, acute postpartum endometritis, bacterial infections of the respiratory tract; pigs for the treatment of bacterial infections of the respiratory tract