Thymogen solution for intravenous injection 0.01%, 1ml No. 5

In the complex therapy of acute and chronic viral and bacterial diseases, accompanied by a decrease in immunity:

• viral hepatitis;

• acute and chronic nonspecific lung diseases (COPD) - chronic bronchitis, acute and chronic pneumonia;

• diseases of the skin and subcutaneous tissue (pyoderma, furunculosis, erysipelas);

• in the complex therapy of severe diffuse forms of atopic dermatitis;

• in the complex therapy of severe mechanical, chemical, radiation and thermal injuries (burn disease);

• complex treatment of wound and surgical infection, incl. purulent-septic complications in the postoperative period;

• during the period of preoperative preparation for planned surgical operations in order to prevent infectious complications and stimulate regeneration processes;

• after radiation therapy, chemotherapy, as well as long-term antibiotic therapy in high doses.

Injected intramuscularly 1 time / day. Adults and children from 14 years old, 100 mcg (300-1000 mcg per course). Children from 6 months to 1 year old - 10 mcg, from 1 year to 3 years old - 10-20 mcg, from 4 to 6 years old - 20-30 mcg, from 7 to 14 years old - 50 mcg The duration of the course of treatment is from 3 to 10 days. A repeated course is possible no earlier than 1 month later. It is possible to conduct 4 courses during the year.

Solution for intramuscular injection is colorless, transparent, odorless.

1 ml alpha-glutamyl-tryptophan sodium (in terms of alpha-glutamyl-tryptophan) 100 mcg

Excipients: sodium chloride - 9000 mcg, water d / i - up to 1 ml.

• Hypersensitivity to the components of the drug;

• children's age up to 6 months.

pharmachologic effect

Immunomodulatory drug. It has a regulating effect on the reactions of cellular, humoral immunity and nonspecific resistance of the organism. Stimulates regeneration processes if they are suppressed. Improves the course of cellular metabolic processes. It enhances the expression of differentiation receptors on lymphocytes, normalizes the number of T-helpers, cytotoxic T-lymphocytes and their ratio in patients with various immunodeficiency states.

Pharmacokinetics

The drug quickly enters the systemic circulation after parenteral administration. Alpha-glutamyl-tryptophan sodium under the influence of peptidases is cleaved into L-glutamic acid and L-tryptophan, which are used by the body in peptide synthesis.

Side effect

Possibly: allergic reactions.

Application during pregnancy and lactation

For safety reasons, due to insufficient data, the appointment of the drug during pregnancy and the period of breastfeeding is possible only if the intended benefit to the mother outweighs the potential risk to the fetus or child. Application in children

It is contraindicated for use in children under 6 months of age.

special instructions

No precautions are required for use. The drug has no peculiarities of action during the first application and when it is canceled. There are no peculiarities of using the drug TimogenЃ in children and adults with chronic diseases. Influence on the ability to drive vehicles and mechanisms The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Overdose

Symptoms of an overdose of TimogenЃ are not described.

Drug interactions

Drug interaction of the drug TimogenЃ has not been identified.