Thrombital Tablets p / o captive, 75mg + 15.20mg, # 30

Amount in a package

thirty

Dosage form

pills

Manufacturer

Pharmstandard, Russia

pharmachologic effect

Thrombital - a combination of acetylsalicylic acid (ASA) and magnesium hydroxide

ASA reduces platelet aggregation mainly by suppressing thromboxane synthesis in platelets, thus disrupting thrombus formation.

Magnesium hydroxide helps to protect the gastrointestinal mucosa from the local irritating effect of ASA and thus improves the tolerance of ASA.

Indications

Primary prevention of cardiovascular diseases such as thrombosis and congestive heart failure in the presence of risk factors (eg, diabetes mellitus, hyperlipidemia, arterial hypertension, obesity, smoking, old age)

Prevention of recurrent myocardial infarction and blood vessel thrombosis

Prevention of thromboembolism after vascular surgery

Unstable angina

How to take, course and dosage

1 tablet per day

Release form

White or white film-coated tablets, round, biconvex

on a cross section, the kernel is white or almost white.

Active substance

Acetylsalicylic acid, [Magnesium hydroxide]

Terms of dispensing from pharmacies

Without recipe

Name ENG

TROMBITAL

Clinical and pharmacological group

Antiplatelet agent

ATX code

Combinations of antiplatelet agents

Dosage

75mg + 15.2mg

Structure

Excipients: microcrystalline cellulose - 12.07 mg, corn starch - 9.5 mg, potato starch - 2 mg, magnesium stearate - 0.15 mg.

Shell composition: hypromellose (hydroxypropyl methylcellulose 15 cps) - 0.6 mg, macrogol (polyglycol 4000) - 0.12 mg, talc - 0.36 mg.

Indications

primary prevention of cardiovascular lesions, including thrombosis and acute heart failure with existing risk factors (eg, arterial hypertension, hyperlipidemia, diabetes mellitus, smoking, obesity, old age)

prevention of blood vessel thrombosis and repeated myocardial infarction

prevention of thromboembolism after surgical interventions on vessels, such as coronary artery bypass grafting, percutaneous transluminal coronary angioplasty

unstable angina.

INN / Active ingredient

magnesium hydroxide + acetylsalicylic acid

Contraindications

Absolute: gastrointestinal bleeding, erosive and ulcerative lesions of the gastrointestinal tract during an exacerbation hemorrhage in the brain chronic heart failure III – IV functional class according to the NYHA classification (New York Heart Association) partial or complete combination of recurrent polyposis rhinosinusitis and bronchial asthma with intolerance to acetylsalicylic acid or any other non-steroidal anti-inflammatory drugs (NSAIDs), including cyclooxygenase-2 (COX-2) inhibitors, including indications in history bronchial asthma caused by the intake of salicylates and other NSAIDs predisposition to bleeding (hemorrhagic diathesis, thrombocytopenia, vitamin K deficiency) renal failure of severe degree with creatinine clearance (CC) below 30 ml / min severe hepatic impairment (child-Pugh grades B and C) deficiency of glucose-6-phosphate dehydrogenase I and III trimesters of pregnancy and lactation concomitant use of methotrexate at a dose of 15 mg per week or more age up to 18 years hypersensitivity to any of the constituents of the drug and other NSAIDs. Relative (take Trombital tablets with extreme caution): a history of gastrointestinal bleeding or erosive and ulcerative gastrointestinal defects impaired renal function (CC above 30 ml / min) liver failure (class A on the Child-Pugh scale) diabetes chronic respiratory diseases, bronchial asthma, nasal polyposis, hay fever, allergic conditions, drug allergies, including in the form of skin reactions, itching,urticaria (since acetylsalicylic acid can lead to bronchospasm, as well as provoke attacks of bronchial asthma or the development of other hypersensitivity reactions) gout, hyperuricemia, since acetylsalicylic acid, taken in small doses, reduces the excretion of uric acid II trimester of pregnancy the proposed surgical intervention (including such a minor one as tooth extraction), since Trombital can cause bleeding for several days after taking it elderly age combined administration with the following drugs: NSAIDs and salicylic acid derivatives in high doses, digoxin, valproic acid, anticoagulants, antiplatelet / thrombolytic agents, methotrexate at a dose below 15 mg per week,insulin and oral hypoglycemic agents (sulfonylurea derivatives), selective serotonin reuptake inhibitors, ethanol (including ethanol-containing drinks), ibuprofen, systemic glucocorticosteroids (GCS), lithium preparations, carbonic anhydrase inhibitors, sulfonamides, narcotic analgesics.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Specifications

Category

Anticoagulants

Scope of the medicinal product

Heart, vessels, blood

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

thirty

Scope of application

Cardiology

Way of introduction

Through the mouth

Mode of application

1 tablet per day

Vacation conditions

Without recipe

Brand name

OTCPharm

The amount of the dosage form in the primary package

30 pcs.

Primary packaging type

Bank

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiplatelet agent

Anatomical and therapeutic characteristics

B01AC30 Platelet aggregation inhibitors in combination

Dosage form

Film-coated tablets

Dosage (volume) of the substance in the preparation

acetylsalicylic acid 75 mg, magnesium hydroxide 15.2 mg

Expiration date in days

730

Package weight, g

ten

Information on technical characteristics, delivery set, country of manufacture