Terzhinan vaginal tablets, No. 10

• Treatment of vaginitis caused by sensitive microorganisms, including: bacterial vaginitis;

• Trichomoniasis of the vagina;

• Vaginitis caused by fungi of the genus Candida;

• Mixed vaginitis.

• Prevention of urogenital infections / vaginitis, including: before gynecological operations;

• Before childbirth or abortion;

• Before and after the installation of the IUD;

• Before and after diathermocoagulation of the cervix;

• Before hysterography.

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Administered intravaginally 1 time / day.

The average duration of a treatment course is 10 days; in the case of confirmed mycosis, the duration of treatment can be increased to 20 days; the average duration of a preventive course is 6 days.

Vaginal tablets are light yellow in color, with possible inclusions of darker or lighter shades, flat, oblong, beveled at the edges and printed in the form of the letter 'T' on both sides.

1 tab.

ternidazole - 200 mg

neomycin sulfate - 100 mg (65,000 IU)

nystatin - 100,000 IU

prednisolone sodium metasulfobenzoate 4.7 mg, which corresponds to the content of prednisolone 3 mg

Excipients: wheat starch - 264 mg, lactose monohydrate - qs up to 1.2 g, colloidal silicon dioxide - 6 mg, magnesium stearate - 10 mg, sodium carboxymethyl starch - 48 mg.

Hypersensitivity to the components of the drug.

Clinical and pharmacological group: A drug with antibacterial, antiprotozoal, antifungal and anti-inflammatory action for local use in gynecology

Pharmaco-therapeutic group: Antimicrobial combined agent (antibiotic + antimicrobial and antiprotozoal agent + antifungal agent + glucocorticosteroid)

pharmachologic effect

Combined drug for topical use in gynecology. Has antimicrobial, anti-inflammatory, antiprotozoal, antifungal effect; ensures the integrity of the vaginal mucosa and the constancy of pH.

Ternidazole - an antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (an integral part of the cell membrane), changes the structure and properties of the cell membrane. It has a Trichomonacid effect and is also active against anaerobic bacteria, in particular Gardnerella spp.

Neomycin is a broad-spectrum antibiotic from the aminoglycoside group. Acts bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) Microorganisms; inactive against Streptococcus spp. Resistance of microorganisms develops slowly and to a small extent.

Nystatin is an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.

Prednisolone - a dehydrated analogue of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.

Indications

• Treatment of vaginitis caused by sensitive microorganisms, including: bacterial vaginitis;

• Trichomoniasis of the vagina;

• Vaginitis caused by fungi of the genus Candida;

• Mixed vaginitis.

• Prevention of urogenital infections / vaginitis, including: before gynecological operations;

• Before childbirth or abortion;

• Before and after the installation of the IUD;

• Before and after diathermocoagulation of the cervix;

• Before hysterography.

Dosage regimen

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Administered intravaginally 1 time / day.

The average duration of a treatment course is 10 days; in the case of confirmed mycosis, the duration of treatment can be increased to 20 days; the average duration of a preventive course is 6 days.

Side effect

Local reactions: rarely - a burning sensation, itching and irritation in the vagina (especially at the beginning of therapy).

Others: in some cases - allergic reactions.

Contraindications for use

Hypersensitivity to the components of the drug.

Application during pregnancy and lactation

It can be used from the second trimester of pregnancy.

Application in the first trimester of pregnancy and during lactation (breastfeeding) is possible only in cases where the expected benefit of therapy to the mother outweighs the potential risk to the fetus or infant.

special instructions

In the case of treatment of vaginitis, trichomoniasis, simultaneous treatment of sexual partners is recommended.

Treatment should not be discontinued during menstruation.