Terbinafine | Thermicon Cream 1%, 15 g
Special Price
$19.40
Regular Price
$27.00
In stock
SKU
BID608746
Latin name
TERMICON
TERMICON
Latin name
TERMICON
Release form
Cream for external use 1% white, uniform, with a slight specific smell.
Packaging
15 g - aluminum tubes (1) - packs of cardboard.
Pharmacological action
Antifungal drug for topical use. It has a wide range of antifungal effects.
Active against dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, Microsporum canis, Epidermophyton floccosum.
In small concentrations, in addition to dermatophytes, terbinafine has a fungicidal effect on mold, yeast (mainly Candida albicans) and certain dimorphic fungi (Pityrospomm orbiculare). Activity against yeast fungi, depending on their type, can be fungicidal or fungistatic.
Terbinafine specifically modifies the early stage of sterol biosynthesis in fungi. This leads to a deficiency of ergosterol and intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus.
Thermicon® does not affect the isoenzymes of the cytochrome P450 system in humans and, accordingly, the metabolism of hormones or other drugs.
Indications
- prevention and treatment of fungal infections of the skin, including foot mycosis (tinea pedis), inguinal epidermophytosis (tinea cruris), fungal infections of the smooth skin of the body (tinea corporis) caused by
dermatophytes - yeast infections of the skin (mainly caused by Candida albicans), in particular, diaper rash
- multicolored versicolor (Pity versity versity ), called by Pityrosporum orbiculare.
Contraindications
- Hypersensitivity to the drug.
Caution should be used in patients with hepatic and / or renal failure, alcoholism, inhibition of bone marrow hematopoiesis, tumors, metabolic diseases, occlusive vascular diseases of the limbs, in children under 12 years of age (lack of sufficient clinical experience).
Use during pregnancy and lactation
To date, no malformations have been reported with Thermicon. However, since the clinical experience with Thermicon during pregnancy is very limited, it should be used only for strict indications.
Terbinafine is excreted in breast milk.
If Thermicon is used by the nursing mother, a small amount of the active substance is absorbed through the skin, therefore, an adverse effect on the baby is unlikely.
In experimental studies of teratogenic properties of terbinafine have not been identified.
Composition of
1 g of terbinafine hydrochloride 10 g of
Dosage and administration
Thermicon® is prescribed topically for adults and children over 12 years of age.
Before applying the cream, clean and dry the affected areas. The cream is applied 1-2 times / day with a thin layer on the affected skin and adjacent areas, gently rubbed.
For infections accompanied by diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the place of application of the cream can be covered with gauze, especially at night.
The average duration of treatment for dermatomycosis of the trunk, legs, feet - 1 time / day for 1 week with skin candidiasis - 1-2 times / day for 1-2 weeks with colored lichen - 1-2 times / day for 2 weeks .
A decrease in the severity of clinical manifestations is usually observed in the early days of treatment. In the case of irregular treatment or premature termination of it, there is a risk of a renewed infection. When, if after 1-2 weeks of treatment there are no signs of improvement, the diagnosis should be verified.
Dosage regimen for elderly patients is the same as for patients of other age groups.
Side effects
Local reactions: redness, itching or burning sensation, allergic reactions are possible at the places where the cream is applied.
No drug interaction
There is no data on the drug's drug interaction.
Overdose
No cases of overdose have been reported.
If Termicon® is accidentally taken orally, you may expect the same symptoms as overdose: headache, nausea, epigastric pain, and dizziness.
Treatment: activated charcoal, if necessary - symptomatic supportive therapy.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 30 РC.
Expiration
2 years. Do not use after the expiry date.
Active ingredient
Terbinafine
Sundlkp pharmacy leave without conditions 24 prescription 5646p46 dfpf dp17 pfpfdfpfd17
pharmacies Over-the-counter
Formulation
Formulation
cream
Pharmstandard-Leksredstva, Russia
TERMICON
Release form
Cream for external use 1% white, uniform, with a slight specific smell.
Packaging
15 g - aluminum tubes (1) - packs of cardboard.
Pharmacological action
Antifungal drug for topical use. It has a wide range of antifungal effects.
Active against dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, Microsporum canis, Epidermophyton floccosum.
In small concentrations, in addition to dermatophytes, terbinafine has a fungicidal effect on mold, yeast (mainly Candida albicans) and certain dimorphic fungi (Pityrospomm orbiculare). Activity against yeast fungi, depending on their type, can be fungicidal or fungistatic.
Terbinafine specifically modifies the early stage of sterol biosynthesis in fungi. This leads to a deficiency of ergosterol and intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus.
Thermicon® does not affect the isoenzymes of the cytochrome P450 system in humans and, accordingly, the metabolism of hormones or other drugs.
Indications
- prevention and treatment of fungal infections of the skin, including foot mycosis (tinea pedis), inguinal epidermophytosis (tinea cruris), fungal infections of the smooth skin of the body (tinea corporis) caused by
dermatophytes - yeast infections of the skin (mainly caused by Candida albicans), in particular, diaper rash
- multicolored versicolor (Pity versity versity ), called by Pityrosporum orbiculare.
Contraindications
- Hypersensitivity to the drug.
Caution should be used in patients with hepatic and / or renal failure, alcoholism, inhibition of bone marrow hematopoiesis, tumors, metabolic diseases, occlusive vascular diseases of the limbs, in children under 12 years of age (lack of sufficient clinical experience).
Use during pregnancy and lactation
To date, no malformations have been reported with Thermicon. However, since the clinical experience with Thermicon during pregnancy is very limited, it should be used only for strict indications.
Terbinafine is excreted in breast milk.
If Thermicon is used by the nursing mother, a small amount of the active substance is absorbed through the skin, therefore, an adverse effect on the baby is unlikely.
In experimental studies of teratogenic properties of terbinafine have not been identified.
Composition of
1 g of terbinafine hydrochloride 10 g of
Dosage and administration
Thermicon® is prescribed topically for adults and children over 12 years of age.
Before applying the cream, clean and dry the affected areas. The cream is applied 1-2 times / day with a thin layer on the affected skin and adjacent areas, gently rubbed.
For infections accompanied by diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the place of application of the cream can be covered with gauze, especially at night.
The average duration of treatment for dermatomycosis of the trunk, legs, feet - 1 time / day for 1 week with skin candidiasis - 1-2 times / day for 1-2 weeks with colored lichen - 1-2 times / day for 2 weeks .
A decrease in the severity of clinical manifestations is usually observed in the early days of treatment. In the case of irregular treatment or premature termination of it, there is a risk of a renewed infection. When, if after 1-2 weeks of treatment there are no signs of improvement, the diagnosis should be verified.
Dosage regimen for elderly patients is the same as for patients of other age groups.
Side effects
Local reactions: redness, itching or burning sensation, allergic reactions are possible at the places where the cream is applied.
No drug interaction
There is no data on the drug's drug interaction.
Overdose
No cases of overdose have been reported.
If Termicon® is accidentally taken orally, you may expect the same symptoms as overdose: headache, nausea, epigastric pain, and dizziness.
Treatment: activated charcoal, if necessary - symptomatic supportive therapy.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 30 РC.
Expiration
2 years. Do not use after the expiry date.
Active ingredient
Terbinafine
Sundlkp pharmacy leave without conditions 24 prescription 5646p46 dfpf dp17 pfpfdfpfd17
pharmacies Over-the-counter
Formulation
Formulation
cream
Pharmstandard-Leksredstva, Russia
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