Tantum verde forte ref. d / local approx. dosage. 0.51mg / dose vial 15ml (88 doses)

Dosage form

colorless transparent liquid with a characteristic mint odor.

Structure

per 100 ml of spray for topical application, dosed 0.51 mg / dose:

Active ingredient: benzydamine hydrochloride 0.30 g

Auxiliary components: glycerol 5.0 g, ethanol 96% 8.0 g, macrogol glyceryl hydroxystearate 1.5 g, menthol flavor (flavoring additive) 0.5 g, methyl parahydroxybenzoate 0.1 g, sodium saccharinate 0.07 g, purified water up to 100 ml.

With one press on the pump, approximately 0.17 g of the drug is released, which corresponds to 0.51 mg of benzydamine hydrochloride.

pharmachologic effect

Benzydamine is a non-steroidal anti-inflammatory drug that belongs to the indazole group.

It has anti-inflammatory and local anesthetic effect, has an antiseptic effect against a wide range of microorganisms.

The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.

Benzydamine has an antibacterial and specific antimicrobial effect due to the rapid penetration of microorganisms through membranes with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes.

Has antifungal action against Candida albicans.

It causes structural modifications of the cell wall of fungi and their metabolic chains, thus interfering with their reproduction, which was the basis for the use of benzydamine in inflammatory processes in the oral cavity, including infectious etiology.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues, is found in blood plasma in an amount insufficient to obtain systemic effects.

Excretion of the drug occurs mainly by the kidneys in the form of inactive metabolites.

Side effects

The classification of the incidence of side effects of the World Health Organization (WHO):

very often -> 1/10

often - from> 1/100 to < 1/10

infrequently - from> 1/1000 to < 1/100

rarely - from> 1/10000 to < 1/1000

very rarely - < 1/10000

frequency unknown - cannot be estimated from the available data.

Local reactions: rarely - dryness, burning sensation in the mouth

frequency unknown - feeling of numbness in the mouth.

Allergic reactions: infrequently - photosensitivity

rarely - hypersensitivity reactions, skin rash, pruritus

very rarely - angioedema, laryngospasm

frequency unknown - anaphylactic reactions.

If any of the side effects indicated in the instructions are aggravated, or other side effects not indicated in the instructions are noted, you should immediately inform your doctor about it.

Selling features

Available without a prescription

Special conditions

When using Tantum® Verde Forte, hypersensitivity reactions may develop.

In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy.

In the presence of ulcerative lesions of the mucous membrane of the oropharynx, the patient should see a doctor if symptoms persist for more than three days.

The use of Tantum® Verde Forte is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.

The drug Tantum® Verde Forte should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm while taking the drug.

Tantum® Verde Forte contains methyl parahydroxybenzoate, which can cause allergic reactions.

Influence on the ability to drive vehicles and use mechanisms

The drug does not affect the ability to drive vehicles and other activities that require increased attention.

Indications

Symptomatic therapy of inflammatory pain syndrome

Name ENG

TANTUM VERDE FORTE

Clinical and pharmacological group

NSAIDs for topical use in ENT practice and dentistry

ATX code

Benzydamine

Dosage

0.51mg / dose x 15ml

Structure

per 100 ml of spray for topical application dosed 0.51 mg / dose: Active ingredient: benzydamine hydrochloride 0.30 g. Auxiliary components: glycerol 5.0 g, ethanol 96% 8.0 g, macrogol glyceryl hydroxystearate 1.5 g, flavor menthol (flavoring) 0.5 g, methyl parahydroxybenzoate 0.1 g, sodium saccharinate 0.07 g, purified water up to 100 ml.

With one press on the pump, approximately 0.17 g of the drug is released, which corresponds to 0.51 mg of benzydamine hydrochloride.

Indications

Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiology):

- gingivitis, glossitis, stomatitis (including after radiation and chemotherapy)

-pharyngitis, laryngitis, tonsillitis

- candidiasis of the oral mucosa (as part of combination therapy)

-calculous inflammation of the salivary glands

-after surgery and trauma (tonsillectomy, jaw fractures)

-after the treatment and tooth extraction

- periodontal disease.

For infectious and inflammatory diseases requiring systemic treatment, it is necessary to use Tantum Verde Forte as part of a combination therapy.

INN / Active ingredient

benzydamine hydrochloride

Storage conditions and periods

In a dark place at a temperature not exceeding 25 degrees.

Expiration date: 4 years

Contraindications

Hypersensitivity to benzydamine or other components of the drug.

Children under 18 years of age.,

Carefully,

Hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including a history).

Specifications

Category

Sore throat

Scope of the medicinal product

Ear, Throat, Nose

Release form

Spray

Manufacturer country

Italy

Package quantity, pcs

one

Way of introduction

On the mucous membrane

Vacation conditions

Without recipe

Volume, ml.

15 ml

Brand name

Angelini francesco

The amount of the dosage form in the primary package

15 ml

Primary packaging type

Polyethylene bottle with a dosing device

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

NSAIDs

Anatomical and therapeutic characteristics

A01AD02 Benzidamine

Dosage form

Dosed topical spray

Dosage (volume) of the substance in the preparation

benzydamine hydrochloride 0.255 mg

Expiration date in days

1460

Package weight, g

35

Mode of application

:

Spray for topical application, dosed 0.51 mg / dose: adults are prescribed 2-4 doses 2-6 times a day.

< br> To use the spray: lift the cannula, insert it into the oral cavity and direct it to the area of ​​inflammation

press the cap (marked with an arrow).

Information on technical characteristics, delivery set, country of manufacture