Tantum rose since. prigot. vag. solution 0.5 g pack. 9.44g # 10

Release form, composition and packaging

Powder for the preparation of vaginal solution in the form of homogeneous white granules, without lumps and foreign particles.

1 sachet

benzydamine hydrochloride 500 mg

trimethyl acetylammonium-p-toluenesulfonate, povidone, sodium chloride.

9.44 g - thermally sealed paper and polypropylene sachets (10) - cardboard boxes.

pharmachologic effect

NSAIDs for topical use, belongs to the indazole group.

It has anti-inflammatory and local analgesic effects, antibacterial, antifungal and antiseptic effects.

The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.

Benzydamine has an antibacterial effect due to the rapid penetration of microorganisms through membranes with subsequent damage to cellular structures, disruption of metabolic processes and cell lysis.

Has antifungal action against Candida albicans.

It causes structural modifications of the cell wall of fungi and the metabolic chains of mycetes and, thus, prevents their reproduction.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues.

Benzydamine is excreted mainly by the kidneys and through the intestines in the form of metabolites or conjugation products.

Indications for use

- in the postpartum period as a therapeutic and prophylactic agent for the prevention of postpartum infectious complications

- specific vulvovaginitis (as part of complex therapy)

- nonspecific vulvovaginitis and cervicovaginitis of any etiology, including those secondary to chemotherapy and radiotherapy

- bacterial vaginosis

- prevention of postoperative infectious complications in operative gynecology.

Contraindications for use

- hypersensitivity to drug components.

Dosage regimen

The drug is used intravaginally.

Powder for preparation of vaginal solution 500 mg (contents of 1 sachet) is dissolved in 500 ml of boiled water.

For a single douching, use 140 ml of the resulting solution.

The prepared solution can be stored for up to 5 days at room temperature.

When reapplying, the solution must be warmed up to body temperature.

The procedure should be carried out lying down, the liquid should remain in the vagina for several minutes.

In the postpartum period, as a therapeutic and prophylactic agent to accelerate the rehabilitation process and prevent postpartum infectious complications, vaginal irrigation is carried out 1 time / day for 3-5 days.

With bacterial vaginosis, the drug is used 1-2 times / day for 7-10 days.

For nonspecific vulvovaginitis and cervicovaginitis of any etiology, including those secondary to chemotherapy and radiotherapy, the drug is used 2 times / day for at least 10 days.

For specific vulvovaginitis (as part of complex therapy), the drug is used 2 times / day for 3-5 days.

For the prevention of postoperative infectious complications in surgical gynecology, the drug is used 1 time / day for 3-5 days.

Overdose

At present, no cases of overdose of the drug TantumRosa have been reported.

Side effect

Rarely: possible allergic reactions, dryness of the oral mucosa.

Drug interactions

There is no clinically significant interaction of TantumRosa with other drugs.

Application during pregnancy and lactation

There are no contraindications to the local use of TantumRosa during pregnancy and lactation (breastfeeding).

special instructions

Long-term use of the drug can lead to hypersensitivity.

When using the drug for a long time

Name ENG

TANTUM ROSA

Clinical and pharmacological group

NSAIDs for topical use in gynecology

ATX code

Benzydamine

Dosage

500mg x 9.44g

Structure

For one sachet of powder for preparation of vaginal solution 500 mg: Active ingredient - benzydamine hydrochloride - 0.500 g. Auxiliary components: trimethylacetylammonium-para-toluenesulfonate, povidone, sodium chloride.

Indications

In the postpartum period as a therapeutic and prophylactic agent for the prevention of postpartum infectious complications.

specific vulvovaginitis (in combination therapy)

nonspecific vulvovaginitis and cervicovaginitis of any etiology, including those secondary to chemotherapy and radiotherapy

bacterial vaginosis

prevention of postoperative infectious complications in operative gynecology.

INN / Active ingredient

Benzydamine

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 5 years

Contraindications

Hypersensitivity to drug components

Specifications

Category

Thrush

Scope of the drug

Metabolism

Release form

Powder

Manufacturer country

Italy

Package quantity, pcs

ten

Way of introduction

Vaginally

Vacation conditions

Without recipe

Brand name

Tantum

The amount of the dosage form in the primary package

9.44 g

Primary packaging type

Sachet (sachet)

Type of consumer packaging

Cardboard box

Pharmaco-therapeutic group

NSAIDs

Anatomical and therapeutic characteristics

G02CC03 Benzydamine

Dosage form

Powder for preparation of vaginal solution

The target audience

Adult

Expiration date in days

1825

Package weight, g

120

Mode of application

:

Powder for preparation of vaginal solution 500 mg - the contents of 1 sachet are dissolved in 500 ml of boiled water.

For a single douching, use 140 ml of the resulting solution.

The prepared solution can be stored for up to 5 days at room temperature.

With repeated use, the solution must be warmed up to body temperature.

Information on technical characteristics, delivery set, country of manufacture