Tantum Verde forte spray 88doses, 15ml

• Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies): gingivitis, glossitis, stomatitis (including after radiation and chemotherapy);

• pharyngitis, laryngitis, tonsillitis;

• oral mucosa candidiasis (as part of combination therapy);

• calculous inflammation of the salivary glands;

• after surgical interventions and injuries (tonsillectomy, jaw fractures);

• after treatment and tooth extraction;

• periodontal disease.

• For infectious and inflammatory diseases requiring systemic treatment, it is necessary to use TantumЃ Verde Forte as part of a combination therapy.

Spray TantumЃ Verde Forte for topical application dosed 0.51 mg / dose: adults are prescribed 2-4 doses 2-6 times a day.

To use the spray: lift the cannula, insert it into the oral cavity and direct it to the area of ??inflammation; press the cap (marked with an arrow).

Benzydamine adheres to the mucous membrane and, due to this, gives a lasting effect. In this regard, the drug should be used after meals.

If it is necessary to use the drug for more than 7 days, a doctor's consultation is required. If after treatment there is no improvement or new symptoms appear, you should consult your doctor.

Active ingredient:

benzydamine hydrochloride 0.30 g

Auxiliary components: glycerol 5.0 g, ethanol 96% 8.0 g, macrogol glyceryl hydroxystearate 1.5 g, menthol flavor (flavoring additive) 0.5 g, methyl parahydroxybenzoate 0.1 g, sodium saccharinate 0.07 g, purified water up to 100 ml.

• Children and adolescents up to 18 years old;

• hypersensitivity to benzydamine or other components of the drug.

• The drug should be used with caution in case of hypersensitivity to acetylsalicylic acid or other NSAIDs; bronchial asthma (including history).

pharmachologic effect

NSAIDs for topical use, belongs to the indazole group. It has an anti-inflammatory and local anesthetic effect, has an antiseptic effect against a wide range of microorganisms. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis. Benzydamine has an antibacterial effect due to the rapid penetration of microorganisms through the membranes with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes. Has antifungal activity against Candida albicans. It causes structural modifications of the cell wall of fungi and metabolic chains, and thus interferes with their reproduction. This property was the basis for the use of benzydamine in inflammatory processes in the oral cavity, incl.infectious etiology.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into the inflamed tissues, is found in the blood plasma in an amount insufficient to obtain systemic effects. Benzydamine is excreted mainly by the kidneys in the form of inactive metabolites or conjugation products.

Side effect

Local reactions: rarely - dryness, burning sensation in the mouth; frequency unknown - feeling of numbness in the mouth. Allergic reactions: infrequently - photosensitivity; rarely - hypersensitivity reactions, skin rash, pruritus; very rarely - angioedema, laryngospasm; frequency unknown - anaphylactic reactions. If any of the side effects indicated in the instructions are aggravated or other side effects not indicated in the instructions are noted, the patient should immediately inform the doctor about it.

Application during pregnancy and lactation

It is not recommended to use the drug during pregnancy and lactation (breastfeeding), because insufficient clinical data.

Application in children

The use of the drug in children and adolescents under 18 years of age is contraindicated.

special instructions

When using the drug TantumЃ Verde Forte, hypersensitivity reactions may develop. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy. In the presence of ulcerative lesions of the mucous membrane of the oropharynx, the patient should see a doctor if symptoms persist for more than 3 days. The use of TantumЃ Verde Forte is not recommended in patients with hypersensitivity to acetylsalicylic acid or other NSAIDs. TantumЃ Verde Forte should be used with caution in patients with a history of bronchial asthma, because possible development of bronchospasm while taking the drug. TantumЃ Verde Forte contains methyl parahydroxybenzoate, which can cause allergic reactions.

Influence on the ability to drive vehicles and use mechanisms

The drug has no effect on the ability to drive vehicles and other activities that require increased attention.

Overdose

Currently, no cases of overdose of TantumЃ Verde Forte have been reported. When using the drug in accordance with the instructions for use, an overdose is unlikely. Symptoms: if the drug is accidentally swallowed, the following symptoms are possible - vomiting, abdominal cramps, anxiety, fear, hallucinations, convulsions, ataxia, fever, tachycardia, respiratory depression. The antidote is unknown. Treatment: gastric lavage is recommended, symptomatic therapy.

Drug interactions

No clinically significant interaction of TantumЃ Verde Forte with other drugs has been established.