Sustilak tab. modif. release p / o captivity. 1500mg # 60

Release form, composition and packaging

Modified release tablets, film-coated white or almost white, oval.

1 tab.

glucosamine hydrochloride 1500 mg

calcium hydrogen phosphate - 62 mg, hypromellose (K200M) - 40 mg, povidone K90 - 40 mg, microcrystalline cellulose - 83 mg, hypromellose (K100M) - 80 mg, colloidal silicon dioxide - 5 mg, stearic acid - 40 mg.

Shell composition: hypromellose E-5 - 20 mg, macrogol-6000 - 6 mg, white opadry (titanium dioxide, macrogol, hypromellose) - 11 mg.

15 pcs.

- contour cell packages (4) - cardboard packs.

pharmachologic effect

Glucosamine helps to prevent the destruction of cartilage, stimulates the restoration of cartilage tissue, has anti-inflammatory and analgesic effects, and normalizes the production of intra-articular fluid.

Improves joint mobility, reduces the need for NSAIDs.

Pharmacokinetics

Absorption and distribution

After oral administration, it is rapidly and completely absorbed in the digestive tract

the prolonged form provides continuous release of the active substance and its uniform absorption

bioavailability of glucosamine after oral administration is 25-26% (undergoes the effect of first pass" through the liver).

After distribution in tissues, the highest concentrations are observed in the liver, kidneys and cartilage tissue.

Metabolism and excretion

It is metabolized to water, carbon dioxide and urea.

It is excreted mainly by the kidneys.

Indications for use

- osteoarthritis of the peripheral joints and spine.

Contraindications for use

- severe renal dysfunction

- pregnancy

- lactation period

- age up to 18 years (efficacy and safety have not been established)

- hypersensitivity to glucosamine and other components of the drug.

The drug should be prescribed with caution for bronchial asthma, diabetes mellitus, intolerance to seafood (shrimp, shellfish).

Dosage regimen

The drug is taken orally.

The tablets are swallowed whole with water.

The recommended dose is 1 tab.

1 time / day for 6-12 weeks.

On the recommendation of a doctor, the course of treatment is repeated at intervals of 2 months.

A stable therapeutic effect is achieved when taking the drug for 6 months.

Overdose

Overdose cases are unknown.

Treatment: gastric lavage, symptomatic therapy.

Side effect

The drug is well tolerated, in some cases the following are possible: gastrointestinal tract dysfunction (epigastric pain, flatulence, constipation or diarrhea, nausea allergic skin reactions (urticaria, itching).

Drug interactions

Increases the absorption of tetracyclines, reduces the effect of semi-synthetic penicillins, chloramphenicol.

The drug is compatible with paracetamol, NSAIDs and GCS.

When used together with NSAIDs, it enhances the anti-inflammatory and analgesic effect of the latter.

Application during pregnancy and lactation

The drug is contraindicated during pregnancy and lactation.

special instructions

The risk of allergic reactions increases with intolerance to seafood.

Influence on the ability to drive vehicles and use mechanisms

There are no restrictions on driving vehicles and complex mechanisms during the period of drug use.

Name ENG

SUSTILAK

Clinical and pharmacological group

A drug that affects the metabolism in cartilage tissue.

Proteoglycan biosynthesis stimulator

ATX code

Glucosamine

Dosage

1.5g

Structure

1 tab.

glucosamine hydrochloride 1500 mg.

Excipients: calcium hydrogen phosphate - 62 mg, hypromellose (K200M) - 40 mg, povidone K90 - 40 mg, microcrystalline cellulose - 83 mg, hypromellose (K100M) - 80 mg, colloidal silicon dioxide - 5 mg, stearic acid - 40 mg.

Shell composition: hypromellose E-5 - 20 mg, macrogol-6000 - 6 mg, white opadry (titanium dioxide, macrogol, hypromellose) - 11 mg.

INN / Active ingredient

Glucosamine

Storage conditions and periods

In a dry, dark place at a temperature not exceeding 25 degrees.

Expiration date: 3 years

Specifications

Scope of the drug

General

Release form

Tablet

Manufacturer country

India

Package quantity, pcs

60

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Medric Ltd IN

The amount of the dosage form in the primary package

15 pcs.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Tissue repair stimulant

Anatomical and therapeutic characteristics

M01AX05 Glucosamine

Expiration date in days

1095

The target audience

Adult

Dosage (volume) of the substance in the preparation

glucosamine hydrochloride 1500 mg

Package weight, g

fifty

Category

:

Joints

,

Treatment of diseases of the musculoskeletal system

,

Synovial fluid

,

Bone metabolism

Mode of application

:

The drug is taken orally.

The tablets are swallowed whole with water.

The recommended dose is 1 tab.

1 time / day for 6-12 weeks.

On the recommendation of a doctor, the course of treatment is repeated at intervals of 2 months.

A stable therapeutic effect is achieved when taking the drug for 6 months.

Dosage form

:

Modified release film-coated tablets

"