Streptocid powder 2g, No. 1

Streptocid powder 2g, No. 1; 'Infectious and inflammatory diseases caused by microorganisms sensitive to sulfonamide, including tonsillitis, erysipelas, cystitis, pyelitis, enterocolitis, infectious diseases of the skin and mucous membranes.

When applied externally, it is applied to the affected areas of the skin and mucous membranes.

sulfonamide

• Severe renal failure

• blood diseases,

• deficiency of glucose-6-phosphate dehydrogenase,

• nephrosis,

• jades,

• acute porphyria

• thyrotoxicosis,

• I and II trimesters of pregnancy,

• lactation,

• hypersensitivity to sulfonamides.

pharmachologic effect

Broad-spectrum antibacterial agent. Sulfanilamide (streptocid) is one of the first representatives of chemotherapeutic agents of the sulfonamide group. Has a bacteriostatic effect. The mechanism of action is due to competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to a disruption in the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, to a disruption in the synthesis of nucleic acids. Sulfanilamide is active against gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Haemophilus influenzae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis.

Side effect

From the digestive system: nausea, vomiting, diarrhea. From the hematopoietic system: rarely - eosinophilia, thrombocytopenia, leukopenia, hypoprothrombinemia, agranulocytosis. From the side of the central nervous system and peripheral nervous system: in isolated cases - visual impairment, headache, dizziness, peripheral neuropathy, ataxia. Others: allergic skin reactions; rarely - nephrotoxic reactions (most likely in patients with impaired renal function); In isolated cases - hypothyroidism.

Application during pregnancy and lactation

Contraindicated for use in the I and II trimesters of pregnancy and lactation.

Application for impaired renal function

Contraindicated in severe renal failure, nephrosis, nephritis. Use with caution in patients with impaired renal function. During the period of treatment, it is necessary to increase the amount of fluid consumed.

Application in children

Application is possible according to the dosage regimen.

special instructions

Use with caution in patients with impaired renal function. During the period of treatment, it is necessary to increase the amount of fluid consumed. If hypersensitivity reactions appear, treatment should be discontinued. With long-term treatment, systematic monitoring of the blood picture, kidney and liver function is recommended.