Strepsils Intensive honey / lemon tab. d / rassas. # 24
Category
Sore throat
Scope of the medicinal product
Ear, Throat, Nose
Release form
Tablet
Manufacturer country
Great Britain
Package quantity, pcs
24
Release form, composition and packaging
?
Lozenges (honey-lemon) are round, made of a translucent caramel mass from light yellow to light brown, with the image of the letter S" on both sides of the tablet
the presence of air bubbles in the caramel mass and slight roughness of the edges are allowed
the appearance of a white coating is possible.
1 tab.
flurbiprofen 8.75 mg
macrogol 300 - 5.47 mg, potassium hydroxide - 2.19 mg, liquid sucrose - 1407 mg, levomenthol - 2 mg, dextrose - 1069 mg, honey - 50.4 mg, lemon flavor (502904 A) - 3.6 mg.
4 things.
- blisters PVC / PVDC / Aluminum (1) - cardboard packs.
4 things.
- blisters PVC / PVDC / Aluminum (2) - packs of cardboard.
4 things.
- blisters of PVC / PVDC / Aluminum (3) - packs of cardboard.
4 things.
- PVC / PVDC / Aluminum blisters (4) - cardboard packs.
4 things.
- blisters PVC / PVDC / Aluminum (5) - packs of cardboard.
6 pcs.
- blisters PVC / PVDC / Aluminum (1) - cardboard packs.
6 pcs.
- blisters PVC / PVDC / Aluminum (2) - packs of cardboard.
6 pcs.
- blisters of PVC / PVDC / Aluminum (3) - packs of cardboard.
6 pcs.
- PVC / PVDC / Aluminum blisters (4) - cardboard packs.
6 pcs.
- blisters PVC / PVDC / Aluminum (5) - packs of cardboard.
8 pcs.
- blisters PVC / PVDC / Aluminum (1) - cardboard packs.
8 pcs.
- blisters PVC / PVDC / Aluminum (2) - packs of cardboard.
8 pcs.
- blisters of PVC / PVDC / Aluminum (3) - packs of cardboard.
8 pcs.
- PVC / PVDC / Aluminum blisters (4) - cardboard packs.
8 pcs.
- blisters PVC / PVDC / Aluminum (5) - packs of cardboard.
10 pieces.
- blisters PVC / PVDC / Aluminum (1) - cardboard packs.
10 pieces.
- blisters PVC / PVDC / Aluminum (2) - packs of cardboard.
10 pieces.
- blisters of PVC / PVDC / Aluminum (3) - packs of cardboard.
10 pieces.
- PVC / PVDC / Aluminum blisters (4) - cardboard packs.
10 pieces.
- blisters PVC / PVDC / Aluminum (5) - packs of cardboard.
12 pcs.
- blisters PVC / PVDC / Aluminum (1) - cardboard packs.
12 pcs.
- blisters PVC / PVDC / Aluminum (2) - packs of cardboard.
12 pcs.
- blisters of PVC / PVDC / Aluminum (3) - packs of cardboard.
12 pcs.
- PVC / PVDC / Aluminum blisters (4) - cardboard packs.
12 pcs.
- blisters PVC / PVDC / Aluminum (5) - packs of cardboard.
pharmachologic effect
NSAIDs for local use in ENT practice and dentistry. Flurbiprofen is a propionic acid derivative from the NSAID group and has a significant analgesic, anti-inflammatory and antipyretic effect due to the suppression of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), with some selectivity in relation to COX-1, as a result which reduces the production of prostaglandins - mediators of pain, inflammation and hyperthermic reaction. The drug has a local analgesic and anti-inflammatory effect on the mucous membrane of the mouth and throat: reduces swelling, difficulty in swallowing, pain and irritation in the throat. The calming effect starts from the 2nd minute. A significant decrease in the intensity of sore throat begins from the 22nd minute with the achievement of the maximum effect after 70 minutes and lasts up to 4 hours.
Pharmacokinetics
Absorption and distribution The tablet dissolves completely in the oral cavity within 5-12 minutes. The degree of absorption is high, flurbiprofen is rapidly and almost completely absorbed, distributed throughout the body and largely binds to plasma proteins. Flurbiprofen is found in the blood after 5 minutes, Cmax of flurbiprofen in blood plasma is reached 40–45 minutes after resorption. Flurbiprofen can be absorbed in the oral cavity by passive diffusion. The absorption rate depends on the dosage form with resorption, the Cmax of flurbiprofen is achieved faster than when flurbiprofen is taken orally in an equivalent dose. Flurbiprofen is excreted in breast milk in small amounts (< 0.05 μg / ml). Metabolism and excretion It is metabolized in the liver by hydroxylation. It is excreted by the kidneys and, to a lesser extent, with bile.T1 / 2 - 3-6 hours. Approximately 20-25% of an oral dose of flurbiprofen in
Name ENG
STREPSILS INTENSIVE
Clinical and pharmacological group
NSAIDs for topical use in ENT practice and dentistry
ATX code
Flurbiprofen
Dosage
8.75mg
Structure
1 lozenge contains:.
Active ingredients: flurbiprofen 8.75 mg
Excipients: macrogol 300 5.47 mg, potassium hydroxide 2.19 mg, lemon flavor [502904 A) 3.6 mg, levomenthol 2 mg, honey 50.4 mg, liquid sucrose 1407 mg, dextrose 1069 mg.
Indications
infectious and inflammatory diseases of the oral cavity and pharynx (as a symptomatic remedy for pain relief).
INN / Active ingredient
flurbiprofen
Contraindications
a history of hypersensitivity reactions (bronchial asthma, bronchospasm, rhinitis, Quincke's edema, urticaria, recurrent polyposis of the nose or paranasal sinuses) in response to the use of acetylsalicylic acid or other NSAIDs
erosive and ulcerative diseases of the gastrointestinal tract (including peptic ulcer and duodenal ulcer, Crohn's disease, ulcerative colitis)
peptic ulcer bleeding in the acute phase or in history (2 or more confirmed episodes of peptic ulcer disease or ulcer bleeding)
a history of bleeding or perforation of a gastrointestinal ulcer, provoked by the use of NSAIDs
deficiency of glucose-6-phosphate dehydrogenase
hemophilia and other blood clotting disorders (including hypocoagulation)
hemorrhagic diathesis
severe liver failure
active liver disease
renal failure of severe severity (CC < 30 ml / min)
confirmed hyperkalemia
decompensated heart failure
period after coronary artery bypass grafting
deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption
pregnancy (III trimester)
children under 12 years of age
hypersensitivity to flurbiprofen or any of the components that make up the drug.,
With caution and only after consulting a doctor, you should take the drug if you have a history of a single episode of gastric ulcer or ulcerative bleeding of the gastrointestinal tract a history of gastrointestinal diseases (ulcerative colitis, Crohn's disease), gastritis, enteritis, colitis, the presence of Helicobacter pylori infection bronchial asthma or allergic diseases in the stage of exacerbation or in history (development of bronchospasm is possible) systemic lupus erythematosus or mixed connective tissue disease (Sharp's syndrome), because increased risk of aseptic meningitis (with short-term use of flurbiprofen, the risk is negligible) renal failure, incl. with dehydration (CC less than 30-60 ml / min), nephrotic syndrome liver failure liver cirrhosis with portal hypertension hyperbilirubinemia arterial hypertension and / or heart failure, edema concomitant use of other NSAIDs the simultaneous use of drugs that can increase the risk of ulcers or bleeding, in particular GCS for oral administration (including prednisolone), anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel ), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) in the I and II trimesters of pregnancy, during breastfeeding elderly patients when drinking alcohol.anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) in the I and II trimesters of pregnancy, during breastfeeding elderly patients when drinking alcohol.anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) in the I and II trimesters of pregnancy, during breastfeeding elderly patients when drinking alcohol.
Storage conditions and periods
At a temperature not higher than 25 degrees.
Expiration date: 3 years
Specifications
Category
Sore throat
Scope of the medicinal product
Ear, Throat, Nose
Release form
Tablet
Manufacturer country
Great Britain
Package quantity, pcs
24
Minimum age from
6 years
Way of introduction
Through the mouth
Vacation conditions
Without recipe
Brand name
Reckitt benckiser
The amount of the dosage form in the primary package
8 pcs.
Primary packaging type
Blister
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
NSAIDs
Anatomical and therapeutic characteristics
R02AX01 Flurbiprofen
Dosage form
Lozenges, [honey-lemon]
Dosage (volume) of the substance in the preparation
flurbiprofen 8.75 mg
The target audience
Children
Expiration date in days
1095
Package weight, g
ten
Mode of application
:
The tablets must be dissolved in the mouth until they are completely dissolved.
When resorption, the tablet should be moved throughout the mouth to avoid damage to the mucous membrane at the site of resorption.
Recommended for adults and children over 12 years of age, one tablet as needed.
Do not take more than five tablets in a 24 hour period.
Do not take tablets for more than 3 days.
Information on technical characteristics, delivery set, country of manufacture "