Stopdiar oral suspension 220mg / 5ml, 90ml

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BIDL3179349
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Expiration Date: 05/2027

Russian Pharmacy name:

Стопдиар суспензия для приема внутрь 220мг/5мл, 90мл

Stopdiar oral suspension 220mg / 5ml, 90ml

Acute bacterial diarrhea, proceeding without deterioration of the general condition, fever, intoxication.

Before taking the drug, shake the bottle several times so that the suspension becomes homogeneous.
The drug can be taken with water.

Children aged 1 to 6 months:

110 mg (1 small scoop of suspension) 2-3 times a day (interval between doses 8-12 hours).

Children aged 6 months to 3 years:

110 mg (1 small scoop of suspension) 3 times a day (interval between doses 8 hours).

Children aged 3 to 6 years: 220 mg (1 large scoop of suspension) 3 times a day (interval between doses 8 hours).

Children aged 6 to 18 years: 220 mg (1 large scoop of suspension) 3-4 times a day (interval between doses 6-8 hours).

Adults: 220 mg (1 large scoop of suspension) 4 times a day (interval between doses 6 hours).

Stopdiar should be used for 5-7 days, but not more than 7 days. If there is no improvement during the first 3 days of taking, then you should consult a doctor.
Use the drug only according to the method of administration and in the doses indicated in the instructions. If necessary, please consult your doctor before using this medication.

in 5 ml

Active ingredient: nifuroxazide - 220 mg

Excipients: carbomer, sucrose, citric acid monohydrate, sodium hydroxide, methyl parahydroxybenzoate, 30% simethicone emulsion (antifoam emulsion), banana flavor, water.

Hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug; fructose intolerance, glucose-galactose malabsorption syndrome or sucrase and isomaltase deficiency; pregnancy; neonatal period up to 1 month, prematurity.

International non-proprietary name

Nifuroxazide.

Tradename:

STOPDIAR.

Description of the dosage form

Suspension of light yellow color, with a banana smell; during storage, the formation of a precipitate is possible, after shaking it returns to the state of a homogeneous suspension.

Ingredients: in 5 ml

Active ingredient: nifuroxazide - 220 mg

Excipients: carbomer, sucrose, citric acid monohydrate, sodium hydroxide, methyl parahydroxybenzoate, 30% simethicone emulsion (antifoam emulsion), banana flavor, water.

pharmachologic effect

Antimicrobial.

Pharmacodynamics

Nifuroxazide is an antimicrobial agent derived from nitrofuran. Blocks the activity of dehydrogenases and inhibits the respiratory chain, the tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell. Destroys the membrane of a microbial cell, reduces the production of toxins by microorganisms.
Highly active against Campylobacteg jejuni, Escherichia coli, Salmonella spp, Shigella spp; Clostgidium pegfringens, Vibgio cholerae, pathogenic Vibrions and Vibrio pagahaemolytique, Staphylococcus spp. The drug is practically not absorbed from the digestive tract, it acts exclusively in the intestinal lumen. Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae and Proteus indologenes. Nifuroxazide resistant: Klebsiella spp, Proteus mirabilis, Providencia spp., Pseudomonas spp. Nifuroxazide does not disturb the balance of the intestinal microflora. In case of acute bacterial diarrhea, it restores intestinal eubiosis. When infected with enterotropic viruses, it prevents the development of bacterial superinfection.

Pharmacokinetics

After oral administration, nifuroxazide is practically not absorbed from the digestive tract and exerts its antibacterial effect exclusively in the intestinal lumen. Nifuroxazide is excreted by the intestines: 20% is unchanged, and the rest of nifuroxazide is chemically altered.

Indications

Acute bacterial diarrhea, proceeding without deterioration of the general condition, fever, intoxication.

Contraindications

Hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug; fructose intolerance, glucose-galactose malabsorption syndrome or sucrase and isomaltase deficiency; pregnancy; neonatal period up to 1 month, prematurity.

Application during pregnancy and lactation

In animal studies, no teratogenic effect was found. However, it is not recommended to take nifuroxazide during pregnancy as a precautionary measure.
During the lactation period, it is possible to continue breastfeeding in the case of a short course of drug treatment.
It is necessary to consult a doctor.

Side effects

Allergic reactions (skin rash, urticaria, Quincke's edema, anaphylactic shock). If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects that are not indicated in the instructions, inform your doctor.

Interaction

Simultaneous use with drugs that cause the development of disulfiram-like reactions, drugs that inhibit the function of the central nervous system is not recommended.
If you are taking other medicines (including over-the-counter medicines), consult your doctor before using Stopdiar.

Method of administration and dosage

Before taking the drug, shake the bottle several times so that the suspension becomes homogeneous.
The drug can be taken with water.

Children aged 1 to 6 months:

110 mg (1 small scoop of suspension) 2-3 times a day (interval between doses 8-12 hours).

Children aged 6 months to 3 years:

110 mg (1 small scoop of suspension) 3 times a day (interval between doses 8 hours).

Children aged 3 to 6 years: 220 mg (1 large scoop of suspension) 3 times a day (interval between doses 8 hours).

Children aged 6 to 18 years: 220 mg (1 large scoop of suspension) 3-4 times a day (interval between doses 6-8 hours).

Adults: 220 mg (1 large scoop of suspension) 4 times a day (interval between doses 6 hours).

Stopdiar should be used for 5-7 days, but not more than 7 days. If there is no improvement during the first 3 days of taking, then you should consult a doctor.
Use the drug only according to the method of administration and in the doses indicated in the instructions. If necessary, please consult your doctor before using this medication.

Overdose

Overdose symptoms are unknown.
Treatment is symptomatic.

special instructions

When treating diarrhea, rehydration therapy should be carried out concurrently with nifuroxazide therapy.
Treatment of diarrhea in children under 3 years of age is recommended under medical supervision.
In the case of bacterial diarrhea with signs of systemic damage (deterioration of the general condition, fever, symptoms of intoxication or infection), you should consult a doctor to decide on the use of antibacterial drugs of systemic action.
If symptoms of hypersensitivity (shortness of breath, rash, itching) appear, the drug should be discontinued.
During therapy, alcohol is prohibited.
Stopdiar contains sucrose. Patients with rare hereditary disorders of fructose tolerance, glucose-galactose malabsorption or sucrase and isomaltase deficiency should not take this drug.
Due to the content of methyl parahydroxybenzoate, Stopdiar may cause allergic reactions (possibly delayed).
One small measuring spoon of the suspension contains 0.09 XE (bread units), one large measuring spoon of the suspension contains 0.18 XE.
The daily dose of the suspension for children aged 1 month to 3 years contains 0.27 XE. The daily dose of the suspension for children aged 3 to 6 years contains 0.54 XE. The maximum daily dose of the suspension for children aged 6 to 18 years contains 0.72 XE. The daily dose of the suspension for adults contains 0.72 XE.

Influence on the ability to drive vehicles and work with mechanisms

The drug does not affect the ability to drive vehicles and mechanisms.

Release form

Oral suspension, 220 mg / 5 ml.
90 ml of suspension in a 125 ml orange glass bottle, equipped with a polyethylene insert, which facilitates pouring out the suspension, sealed with a polyethylene screw cap.
1 bottle together with a double dosing spoon made of polystyrene with a capacity of 2.5 ml and 5 ml and instructions for use in a cardboard box.

Conditions of dispensing from pharmacies

Without recipe.

Storage conditions

At a temperature not exceeding 25 ? C.
Keep out of the reach of children.

Shelf life

3 years.
Do not use after the expiration date printed on the package.
An opened bottle should be stored for no more than 14 days.

Manufacturer

LLC 'Gedeon Richter Poland'. 05-825, Grodzisk Mazowiecki, st. book Y. Poniatowski, 5, Poland.
The owner of the RU: Gedeon Richter OJSC. Budapest, st. Demrei, 19-21, Hungary.
Consumer claims should be sent to the following address: Moscow Representative Office of Gedeon Richter OJSC. 119049, Moscow, 4th Dobryninsky per., 8.
Tel .: (495) 363-39-50; fax: (495) 363-39-49.

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