Stop-coccid 5% (Stop-coccid) suspension for oral administration 250ml

DESCRIPTION

Dosage form: suspension for oral administration. In appearance, the drug is a white liquid; stratification is allowed during storage.

COMPOSITION

Stop-coccid in 1 ml contains toltrazuril - 50 mg as an active ingredient (DV), as well as auxiliary substances: sodium benzoate - 1.5 mg, carboxymethyl cellulose - 1.5 mg, cyclamate - 0.67 mg, saccharin - 0, 67 mg, aspartame - 0.67 mg, lactose - 2 mg, polypropylene glycol - 100 mg, Tween-80 - 6 mg, Aerosil - 6 mg and distilled water - up to 1 ml.

PHARMACOLOGICAL PROPERTIES

Stop-coccid is one of the anti-coccidial drugs of the triazintrione group. Toltrazuril, which is part of the drug, has a wide spectrum of coccidicidal action at the stages of intracellular development of parasites, is effective against all types of coccidia, including Eimeria spp., Isospora spp., Cistoisospora spp., Parasitizing in pigs, calves, lambs and dog puppies. Toltrazuril has a damaging effect on mitochondria and the processes of fission of the nucleus of coccidia, disrupting the formation of macrogametocytes, blocking respiratory enzymes, which leads to the death of parasites. After oral administration of the drug, toltrazuril is slowly absorbed and has a coccidiocidal effect on the mucous and submucosal membranes of the gastrointestinal tract. In the body, toltrazuril is metabolized by sulfooxidation and hydroxylation, to form sulfoxide and sulfone. It is excreted from the body mainly unchanged - up to 70%, and also in the form of metabolites with feces and partly with urine.

According to the degree of impact on the body, the drug belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in recommended doses does not cause side effects and complications in animals, does not prevent the formation of immunity to coccidiosis.

INDICATIONS

The drug is prescribed to calves, lambs, kids, piglets and puppies of dogs for the treatment and prevention of coccidiosis.

APPLICATION

Stop-coccid is administered orally to animals individually using a syringe dispenser. If sediment appears, the container with the suspension should be shaken thoroughly before use.

Doses and dosage regimens of the drug are presented in the table:

Kind of animal Age Dose of medicinal product per 1 kg of animal weight Frequency rate and duration of drug use

DV, mg / kg suspension, ml / kg

Calves, lambs and kids from 14 days 15 0.3 once

Piglets from 3 days 20 0.4 (not less than 0.5 and not more than 2 ml / animal) once

Dog puppies from 14 days ten 0.2 Once a day, 3 days in a row

In dysfunctional farms for coccidiosis, to achieve the maximum prophylactic effect and reduce the number of oocysts released into the environment, the drug should be administered to susceptible animals before the first clinical signs of the disease appear in the herd.

It is prohibited to use Stop-coccid after the expiration date.

CONTRAINDICATIONS

Contraindication to the use of Stop-coccid is the increased individual sensitivity of the animal to the components of the drug, serious violations of the liver and / or kidneys.

It is forbidden to use the drug in dairy animals, due to its excretion in milk; the drug should not be used in adult ruminants with developed cicatricial digestion.

Stop-coccid should not be used concurrently with other anticoccid drugs. There is no information on the incompatibility of the drug with drugs of other groups and feed additives.

OVERDOSE

In case of an overdose of the drug, the animal may experience a decrease in appetite, a decrease in water consumption, and an upset of the gastrointestinal tract.

SPECIAL INSTRUCTIONS

Failure to comply with the recommended interval for repeated administration of the drug to puppies can lead to a decrease in its effectiveness. If the next dose of the drug is missed, it should be administered as soon as possible.

SIDE EFFECTS

When using Stop-coccid in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. With increased individual sensitivity to the drug and the appearance of allergic reactions, the animal is prescribed antihistamines and symptomatic therapy.

Slaughter of calves, lambs and kids for meat is allowed no earlier than 70 days, piglets - no earlier than 91 days after the application of Stop-Coccid. The meat of animals that were forcedly killed earlier than the established deadlines can be used as feed for fur animals.

SHELF LIFE AND STORAGE

Stop-coccid should be stored in places inaccessible to children, in the manufacturer's closed packaging, in a dry, dark place, separate from food and feed, at a temperature from 0 В° C to 25 В° C. The shelf life of the medicinal product, subject to storage conditions in a sealed package, is 3 years from the date of production. Unused medicinal product is disposed of in accordance with legal requirements.

PACKAGING

The drug is produced in 250 ml polymer vials with screw caps for the first opening control, complete with a syringe-dispenser.

Specifications

KolVUP

ten

Manufacturer

APICENNA

Teaser

prescribed to calves, lambs, kids, piglets and puppies of dogs for the treatment and prevention of coccidiosis