Stomatidin solution, 200ml

• Infectious and inflammatory diseases of the oral cavity and pharynx: tonsillitis (including tonsillitis with lesions of the lateral ridges, Plaut-Vincent sore throat), pharyngitis, gingivitis, bleeding gums, periodontopathy, stomatitis, glossitis, aphthous ulcers in order to prevent superinfection;

• in order to prevent infection of the alveoli after tooth extraction;

• fungal infections of the oral cavity and pharynx (especially candidal stomatitis);

• before and after operations in the oral cavity and pharynx;

• additional oral hygiene for common diseases;

• in order to eliminate bad breath, especially in the case of collapsing tumors of the oral cavity and pharynx.

Locally.

Always use undiluted product for rinsing. The solution must not be swallowed. It is necessary to spit out the solution after rinsing.

For diseases of the oral cavity in adults and children over the age of 5 years, rinse the mouth with 10-15 ml (1 tablespoon) of undiluted drug solution for 30 s.

For throat diseases in adults and children over the age of 5 years, rinse with the same amount of undiluted drug solution for 30 seconds.

When treating diseases of the oral cavity, the drug can be applied using a tampon.

Apply 2 times a day (preferably in the morning and in the evening), after meals. The duration of the drug is set individually. If the symptoms of the disease do not disappear after 5 days of using the drug and / or are accompanied by a fever, you should consult a doctor.

Solution for topical application in the form of a transparent liquid of red color.

1 ml hexetidine 1 mg

Excipients: propylene glycol - 100 mg, polysorbate 20 - 10 mg, citric acid monohydrate - 0.4 mg, sodium saccharinate - 0.3 mg, racementol - 0.15 mg, methyl salicylate - 0.1 mg, azorubin dye - 0.1 mg, ethanol 96% - 0.1 ml, water - up to 1 ml.

• Atrophic pharyngitis;

• children under 5 years of age;

• I trimester of pregnancy;

• hypersensitivity to the components of the drug.

pharmachologic effect

Antiseptic preparation for local use in ENT practice and dentistry.

The antimicrobial effect of hexetidine is associated with the suppression of oxidative reactions of the metabolism of microbial cells (thiamine antagonist).

The drug has an antibacterial effect against gram-negative and gram-positive bacteria, Pseudomonas aeruginosa and Proteus spp. and antifungal action (including against fungi of the genus Candida). At a concentration of 100 mg / ml, inhibition of the growth of most bacterial strains is achieved.

No development of resistance was observed.

Hexetidine has a weak analgesic effect on the mucous membrane.

Pharmacokinetics

Hexetidine adheres well to the mucous membrane and is practically not absorbed. After a single application, hexetidine is found on the oral mucosa for 65 hours. In dental plaques, active concentrations remain for 10-14 hours after application.

Side effect

Local reactions: burning, irritation and moderate dryness of the oral mucosa.

Others: allergic reactions; with prolonged use, a change in taste is possible.

After stopping the use of the drug, side effects disappear.

Application during pregnancy and lactation

There are insufficient data on the penetration of hexetidine through the placental barrier and on excretion in breast milk.

The use of the drug in the first trimester of pregnancy is contraindicated. It is possible to use the drug in the II and III trimesters of pregnancy if the potential benefit to the mother outweighs the risk to the fetus.

If it is necessary to use the drug during lactation, it is necessary to decide on the termination of breastfeeding.

Application in children

The drug is contraindicated in children under 4 years of age.

special instructions

Do not use the drug in a category of patients who cannot carry out this procedure on their own (rinsing).

Influence on the ability to drive vehicles and mechanisms

The drug contains 10% ethanol (ethyl alcohol 96%). The drug should be taken no later than 30 minutes before driving.

Overdose

Symptoms: if large amounts of the drug are accidentally swallowed, nausea and vomiting may occur.

Treatment: gastric lavage, symptomatic therapy.