Snoop spray 0.05%, 15ml

• Acute respiratory diseases with symptoms of rhinitis (rhinitis);

• acute allergic rhinitis;

• hay fever;

• sinusitis;

• eustachitis;

• otitis media (as part of combination therapy to reduce swelling of the nasopharyngeal mucosa);

• to facilitate rhinoscopy and other diagnostic procedures in the nasal passages.

Intranasally.

SnoopЃ nasal spray dosed 45 mcg / dose

Children aged 2 to 5 years, 1 injection into each nasal passage 1-3 times / day.

Adults and children from 6 years old, 1-2 injections into each nasal passage 2-3 times / day.

Should not be used more than 3 times / day.

SnoopЃ nasal spray dosed 90 mcg / dose

Adults and children from 6 years old, 1 injection into each nasal passage 2-3 times / day.

Should not be used more than 3 times / day.

In children, the drug should be used under adult supervision.

It is recommended that the last injection be carried out just before bedtime.

Before use, you must clean the nasal passages.

When using the nozzle, insert it into the nasal cavity and press the rim once. Keep the bottle upright. Do not spray horizontally or downward. It is recommended to inhale slightly through the nose immediately after injection. After use, close the bottle with a protective cap.

Each bottle should be used individually.

After completion of therapy, the drug can be re-prescribed only after a few days.

The duration of use in children should be consulted with a doctor.

If after treatment there is no improvement or the symptoms worsen, or new symptoms appear, the patient should consult a doctor.

The drug should be used only according to the indications, the method of administration and the doses indicated in the instructions.

Dosed nasal spray in the form of a colorless transparent solution.

1 dose of xylometazoline hydrochloride 45 mcg

Excipients: sea water, potassium dihydrogen phosphate, purified water.

• Hypersensitivity to xylometazoline and any other component of the drug;

• arterial hypertension;

• tachycardia;

• severe atherosclerosis;

• increased intraocular pressure, especially angle-closure glaucoma;

• atrophic rhinitis;

• hyperthyroidism;

• surgical interventions on the meninges (in history);

• inflammatory diseases of the skin or mucous membrane of the vestibule of the nose;

• conditions after transsphenoidal hypophysectomy;

• pregnancy;

• children under 6 years of age (for 0.1% solution);

• children under 2 years of age (for a 0.05% solution).

Do not use during therapy with MAO inhibitors (including 14 days after their cancellation), tricyclic and tetracyclic antidepressants, other local vasoconstrictor agents (decongestants), as well as other drugs that increase blood pressure.

Carefully

Diabetes mellitus, severe cardiovascular diseases (including coronary artery disease, angina pectoris), prostatic hyperplasia, pheochromocytoma, porphyria, breastfeeding, with hypersensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.

pharmachologic effect

Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity. It causes narrowing of the blood vessels of the nasal mucosa, eliminating edema and hyperemia of the nasal mucosa, restores the patency of the nasal passages, and facilitates nasal breathing.

The action of the drug occurs 5-10 minutes after its application and lasts up to 12 hours.

Pharmacokinetics

When applied topically, the drug is practically not absorbed, therefore its concentration in the blood plasma is very low (it is not determined by modern analytical methods).

Side effect

From the immune system: very rarely - hypersensitivity reactions (angioedema, rash, itching).

From the nervous system: often - headache; rarely - insomnia, depression (with prolonged use in high doses); very rarely - anxiety, fatigue, paresthesia, hallucinations and convulsions (mainly in children).

From the senses: very rarely - a violation of the clarity of visual perception.

From the side of the cardiovascular system: rarely - a feeling of palpitations, increased blood pressure; very rarely - tachycardia, arrhythmia.

From the respiratory system: often - irritation and / or dryness of the nasal mucosa, burning, tingling, sneezing, hypersecretion of the nasopharyngeal mucosa; rarely - after using the drug, there may be an increase in edema of the nasal mucosa (reactive hyperemia), nosebleeds.

From the digestive system: often - nausea; rarely - vomiting.

Local reactions: often - burning at the site of application.

If the patient develops or aggravates the above side effects, or any other side effects are noted, he should inform the doctor about it.

Application during pregnancy and lactation

During pregnancy, the use of the drug is contraindicated.

During the period of breastfeeding, the drug should be used only after a careful assessment of the risk-benefit ratio for the mother and the child, it is not allowed to exceed the recommended dose. During breastfeeding, you should consult your doctor before using SnoopЃ.

Application in children

Contraindication: children under 6 years of age (for nasal spray dosed 90 mcg / dose); children under 2 years of age (for nasal spray dosed 45 mcg / dose).

special instructions

Sea water, which is part of the drug, helps to maintain the normal physiological state of the mucous membrane of the nasal cavity due to the ability to improve the function of the ciliated epithelium and normalize the production of mucus in the goblet cells of the mucous membrane.

It is not recommended to apply continuously for more than 7 days.

The recommended doses should not be exceeded, especially in children and elderly patients.

Long-term (more than 7 days) use or overdose of xylometazoline can weaken the therapeutic effect of the drug, and also increase the risk of reactive hyperemia and atrophy of the nasal mucosa.

Patients with long QT syndrome receiving xylometazoline may be at increased risk of developing serious ventricular arrhythmias.

If a medicinal product has expired, it should not be thrown into wastewater or outdoors. Place the medication in the trash can. These measures will help protect the environment.

Influence on the ability to drive vehicles and mechanisms

If the dosage regimen is observed, xylometazoline does not affect concentration and psychomotor speed.

Overdose

Symptoms: in case of an overdose of the drug, the clinical picture is an alternation of phases of excitation of the central nervous system (anxiety, excitement, hallucinations, convulsions) with phases of depression of the central nervous system (decrease in body temperature, lethargy, drowsiness, coma). The following symptoms may also occur: miosis, mydriasis, increased sweating, fever, pallor, cyanosis, nausea and vomiting, tachycardia, bradycardia, cardiac arrhythmias, cardiac arrest, palpitations, increased blood pressure, decreased blood pressure up to shock, pulmonary edema, depression breathing and apnea, psychogenic disorders.

In children with overdose, dominant central effects are observed with convulsions, coma and bradycardia, apnea, as well as an increase in blood pressure, followed by arterial hypotension.

Treatment: symptomatic, under medical supervision.

In case of accidental ingestion of the drug inside - the introduction of activated carbon, gastric lavage.

In case of severe overdose, intensive care is indicated in a hospital. In severe cases, non-selective alpha-blockers can be used to lower blood pressure, antipyretics, intubation, and mechanical ventilation.

Drug interactions

The simultaneous use of xylometazoline with MAO inhibitors, tricyclic and tetracyclic antidepressants, other local vasoconstrictors (decongestants), as well as other drugs that increase blood pressure, can lead to an increase in blood pressure, therefore, the simultaneous use of these drugs is contraindicated. If the patient uses the above or other drugs (including over-the-counter), consult a doctor before using SnoopЃ.