Sialor tablets for solution preparation 200mg, 10ml

Locally, in the form of a 2% solution.

Prepare the solution immediately before use.

Store the prepared solution at room temperature. Use the solution within 30 days after preparation.

To prepare a 2% solution, 1 tablet of the drug (200 mg) is dissolved in 10 ml of a solvent (water for injection).

Method of preparation of the drug solution before use:

1. Pour the solvent into the bottle

2. Add the Sialor tablet to the bottle

3. Shake until the tablet is completely dissolved (about 15 minutes)

Before using the drug, it is recommended to rinse and clean the nasal passages.

Children from 3 to 6 years old - 1-2 drops in each nasal passage 3 times a day.

Adults and children over 6 years old - 2-3 drops in each nasal passage 3 times a day. The duration of the course of treatment is 5-7 days.

If after 7 days of treatment there is no improvement or symptoms worsen, or new symptoms appear, you should consult your doctor.

Use the drug only according to the indications, the route of administration and the doses indicated in the instructions.

Composition for one tablet

Active substance:

Silver proteinate - 200 mg

Excipient: povidone K 30 - 20 mg

1 ampoule of solvent contains: water for injection.

• Hypersensitivity to the drug,

• pregnancy, lactation period,

• atrophic rhinitis,

• children's age up to 3 years

Pharmacodynamics

Silver preparation (silver proteinate contains 7.5-8.5% silver). It has an astringent, antiseptic and anti-inflammatory effect. Dissociates to form silver ions, which bind to bacterial DNA and prevent them from multiplying on mucous membranes under conditions of topical application. The mechanism of action of silver proteinate is based on the fact that silver ions precipitate proteins and form a protective film on the damaged mucous membrane, which helps to reduce the sensitivity of nerve endings and narrowing of blood vessels (this leads to a decrease in edema), which in turn causes inhibition of inflammatory reactions. Silver ions also inhibit the growth of various bacteria. It is active against gram-positive and gram-negative microorganisms: B. cereus, C. albicans, E. coli, P. aeruginosa, S. aureus, A. niger, S.Abony and others.

Pharmokinetics

When applied topically, it is practically not absorbed.

Special conditions

It is possible to stain the discharge from the nose in gray or blue.

Influence on the ability to drive vehicles, mechanisms

Does not affect.

Drug interactions

Pharmacodynamic, pharmacokinetic interaction: not studied. Pharmaceutical interaction: salts of zinc, copper, lead, silver, mercury, iron, aluminum form insoluble precipitates with the drug solution; the solution of the drug is inactivated by alkaloid salts and organic bases (epinephrine).

If you are using the above or other drugs (including over-the-counter), consult your doctor before using the drug.

Overdose

With the recommended route of administration, overdose is unlikely.

Symptoms: Possible increased side affects. If a large amount is accidentally swallowed, it may cause irritation of the gastrointestinal tract.

Treatment: in case of severe irritation, burning, itching of the mucous membranes, rinse with plenty of water for 15 minutes. If symptoms persist, seek medical attention. Treatment is symptomatic.

Side effects

Slight irritation of the mucous membrane, burning, itching, allergic reactions (urticaria, atopic dermatitis, Quincke's edema, anaphylactic shock).

If you have any side effects indicated in the instructions or they are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor about it.