Septolete Total tablets elderberry-lemon, No. 16
Expiration Date: 05/2027
Russian Pharmacy name:
Септолете Тотал таблетки бузина-лимон, №16
The tablets should be slowly dissolved in the mouth every 3-6 hours.
Adults, elderly patients and children over 12 years of age
The recommended dose is 3-4 tablets per day.
Children from 6 to 12 years old
The recommended dose is 3 tablets per day.
Do not exceed the indicated dose.
SeptoleteЃ total should not be used concurrently with other drugs from the antiseptic group.
SeptoleteЃ total should not be used for more than 7 days.
Active ingredients:
Benzydamine hydrochloride 3,000 mg
Cetylpyridinium chloride monohydrate 1.050 mg,
equivalent to cetylpyridinium chloride 1,000 mg
Excipients: isomalt (type M) (E953), citric acid (E330), elderberry flavor, sucralose (E955), citrus flavor, levomenthol, dye curcumin (E100) 1), dye chlorophyllin copper complex (E141), peppermint butter
Hypersensitivity to active ingredients, or to any auxiliary components of the drug. Children under 6 years of age.
With caution Hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including history).
Pharmacodynamics
Benzydamine is a non-steroidal anti-inflammatory drug that has anti-inflammatory, analgesic and local anesthetic effects. Cetylpyridinium chloride - an antiseptic from the group of quaternary ammonium compounds, has antimicrobial, antifungal, virucidal effect.
Pharmokinetics
Suction
Of the two active ingredients, cetylpyridinium chloride and benzydamine, only benzydamine is absorbed through the mucous membranes. Therefore, cetylpyridinium chloride does not enter into pharmacokinetic interaction with benzydamine at the systemic level.
The absorption of benzydamine through the mucous membranes of the oral cavity and pharynx was shown by identifying the active substance in the blood serum, the amount of which, however, was insufficient to provide a systemic effect. The absorption of benzydamine is higher when using dosage forms that dissolve in the oral cavity compared to dosage forms for topical application (for example, oral spray).
Distribution
The volume of distribution of all dosage forms is the same.
Withdrawal
Excretion occurs mainly by the kidneys, to a greater extent, in the form of inactive metabolites. The half-life and total clearance are similar for all dosage forms.
Special conditions
SeptoleteЃ total should not be used for more than 7 days. In the absence of noticeable signs of improvement, you should consult a doctor.
When using the drug SeptoleteЃ total, hypersensitivity reactions may develop. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy.
In the presence of ulcerative lesions of the mucous membrane of the oropharynx, the patient should see a doctor if symptoms persist for more than three days.
The use of SeptoleteЃ Total is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
SeptoleteЃ Total should not be used simultaneously with anionic compounds (for example, present in toothpaste). To achieve an optimal effect, you should not use SeptoleteЃ Total immediately before or after brushing your teeth.
Simultaneous administration with milk can reduce the antimicrobial effect of cetylpyridinium chloride, therefore SeptoleteЃ Total should not be used simultaneously with milk.
Influence on the ability to drive vehicles, mechanisms
SeptoleteЃ total does not affect the ability to drive vehicles and work with mechanisms.