Senadexin tablets, no. 20

• Constipation due to hypotension and sluggish motility of the colon.

• Stool regulation for hemorrhoids, proctitis, anal fissures;

• spastic and atonic constipation of various etiologies.

Senadexin is taken at bedtime.

Adults and children over 12 years old: 1-2 tablets. If there is no effect, the dosage of the drug is increased to 3 tablets per dose (a few days after the first dose). Children 1-6 years old are prescribed 1/3 of the tablet. Children 6-12 years old - half the adult dosage.

For one tablet:

Active ingredient

Senadexin -0.07 g

[The sum of calcium salts of sennosides A and B from cassia (senna) holly leaves in terms of dry matter 20.0%]

Excipients

Corn starch - 0.1370 g

Lactose monohydrate - 0.0340 g Talc - 0.0049 g

Calcium stearate - 0.0020 g

Magnesium stearate - 0.0015 g

Vanillin - 0.0003 g

Methyl parahydroxybenzoate (nipagin) - 0.0003 g

• Intestinal obstruction

• abdominal pain of unknown origin,

• disorders of water and electrolyte metabolism,

• strangulated hernia,

• acute inflammatory diseases of the abdominal organs,

• peritonitis,

• bleeding from the gastrointestinal tract,

• uterine bleeding

• cystitis,

• spastic constipation.

Trade name of the drug

Senadexin

International non-proprietary name

Sennosides A and B

Dosage form

pills

Composition

For one tablet:

Active ingredient

Senadexin -0.07 g

[The sum of calcium salts of sennosides A and B from cassia (senna) holly leaves in terms of dry matter 20.0%]

Excipients

Corn starch - 0.1370 g

Lactose monohydrate - 0.0340 g Talc - 0.0049 g

Calcium stearate - 0.0020 g

Magnesium stearate - 0.0015 g

Vanillin - 0.0003 g

Methyl parahydroxybenzoate (nipagin) - 0.0003 g

Description

Tablets are round, flat-cylindrical, beveled and scored, from grayish-brown to brown in color with darker and lighter blotches with a weak characteristic odor.

pharmachologic effect

Herbal laxative. Senna leaves contain dianthrone glycosides (about 3%) - sennosides A, A1, BG; a small amount of anthraquinone glycosides, incl. aloe-emodin and rhein 8-glycosides; about 10% mucus; flavonoids, incl. camferol derivatives; naphthalene glycosides.

Stimulates colon peristalsis, causes normal stools 8-10 hours after ingestion. Selectively affects the colon, restores normal bowel function, is non-addictive and does not affect digestion.

Side effect

Possibly: flatulence, colicky abdominal pain.

With prolonged use, especially in high doses, - loss of electrolytes (mainly potassium), albuminuria and hematuria, deposition of melanin in the intestinal mucosa, damage to the intermuscular plexus.

Application during pregnancy and lactation

Use with caution during pregnancy and lactation.

Application for violations of liver function

Use with caution in liver diseases.

Application for impaired renal function

Use with caution in kidney disease.

special instructions

Use with caution in liver and / or kidney diseases. Can be used for preoperative patient preparation.

Release form / dosage:

Pills.

Packaging:

10 tablets in a blister strip or bezelzheykovuyu packaging. 2 or 3 blister packs together with instructions for use are placed in a cardboard box. 60 or 200 contour non-cell packs, together with an equal number of instructions for use, are placed in a box or in a cardboard box (for hospitals).

Vacation conditions

On prescription