Selank nasal drops 0.15%, 3ml

Anxiety states:

• unmotivated anxiety, worry;

• panic attacks;

• neurasthenia;

• asthenia;

• instability of mood;

• sleep disorders;

• decreased will, initiation of activity, indecision, difficulty in making decisions, self-doubt;

• lack of confidence in communication;

• adjustment disorders; Prevention and Treatment of Stress Disorders.

SelankЃ is administered intranasally using a bottle sealed with a plastic screw cap or dropper cap.

If the vial is sealed with a plastic screw cap, upon initial use, remove the plastic screw cap and replace it with the supplied pipette with cap. Draw up the drug into a pipette.

Squeeze the required number of drops of the drug onto the clean mucous membrane of the nasal passage, then pinch the nostril with your finger for a short time.

If the bottle is sealed with a dropper cap, carefully cut off the tip of the pipette, tightly close the pipette cap. Invert the bottle before use so that the liquid fills the entire space of the pipette. Remove the cap. Squeeze the required number of drops of the drug onto the clean mucous membrane of the nasal passage, then pinch the nostril with your finger for a short time. The instillation of the drug into the nasal passages is carried out in a sitting position with the head slightly thrown or tilted to one side, after which each nostril is clamped with a finger for a short time. The effectiveness of absorption may be reduced in the presence of increased secretions of the nasal mucosa, therefore, it is recommended to clear the nasal passage before use (instillation).

Dose: 2 drops in each nasal passage 3 times a day.

The duration of the course of the drug is 14 days. If necessary, the course of treatment can be repeated after 1-3 weeks, after consulting a doctor.

Use the drug only according to the method of administration and in the doses indicated in the instructions. If necessary, please consult your doctor before using this medication.

for 1 ml:

Active ingredient: SelankaЃ in terms of 100% substance (threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline diacetate) - 1.5 mg.

Excipients: methyl parahydroxybenzoate (nipagina) - 1 mg, purified water up to 1 ml. Description: colorless transparent liquid.

Individual intolerance to the drug.

Pregnancy, breastfeeding period (efficacy and safety studies have not been conducted).

Children under 18 years of age (efficacy and safety studies have not been conducted).

Application during pregnancy and during breastfeeding

Pregnancy

Since no controlled studies have been conducted on the use of SelankЃ in pregnant women, it should not be used during pregnancy. Breastfeeding period

If you need to use the drug during lactation, you should refrain from breastfeeding.

Trade name of the drug:

SelankЃ

Chemical name

threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline-diacetate.

Dosage form:

nasal drops

Composition

for 1 ml:

Active ingredient: SelankaЃ in terms of 100% substance (threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline diacetate) - 1.5 mg.

Excipients: methyl parahydroxybenzoate (nipagina) - 1 mg, purified water up to 1 ml. Description: colorless transparent liquid.

Pharmacotherapeutic group

anxiolytic agent (tranquilizer).

ATX code: N05BX

Pharmacological action
Pharmacodynamics

SelankЃ is a synthesized analogue of endogenous peptide taftcin, has an original mechanism of neurospecific action on the central nervous system.

SelankЃ has an anti-anxiety effect with an antidepressant effect; antiasthenic action.

Relieves symptoms of anxiety, anxiety, fear, apathy, depression and asthenia.

It has a positive effect on cognitive functions, improves memory, speech, increases attention, activates learning processes, in particular, memorization, analysis and reproduction of information. Normalizes psychomotor reactions.

When stressed, SelankЃ eliminates negative emotional stress and stimulates the development of adaptive behavior aimed at achieving a beneficial result.

Pharmacokinetics

SelankЃ is administered intranasally (nasal drops). The absolute bioavailability of SelankЃ when administered to the nasal mucosa is 92.8%. The drug is rapidly absorbed from the nasal mucosa and after 30 seconds is found in the blood plasma, and then rapidly distributed to various organs and tissues. Penetrates into the brain tissue. Plasma concentration decreases progressively within 5-5.5 minutes. In daily urine, neither unchanged drug nor metabolites are detected, which is due to the rapid degradation of SelankЃ under the influence of tissue peptidases.

Indications for use

Anxiety states:

• unmotivated anxiety, worry;

• panic attacks;

• neurasthenia;

• asthenia;

• instability of mood;

• sleep disorders;

• decreased will, initiation of activity, indecision, difficulty in making decisions, self-doubt;

• lack of confidence in communication;

• adjustment disorders; Prevention and Treatment of Stress Disorders.

Contraindications

Individual intolerance to the drug.

Pregnancy, breastfeeding period (efficacy and safety studies have not been conducted).

Children under 18 years of age (efficacy and safety studies have not been conducted).

Application during pregnancy and during breastfeeding

Pregnancy

Since no controlled studies have been conducted on the use of SelankЃ in pregnant women, it should not be used during pregnancy. Breastfeeding period

If you need to use the drug during lactation, you should refrain from breastfeeding.

Method of administration and dosage

SelankЃ is administered intranasally using a bottle sealed with a plastic screw cap or dropper cap.

If the vial is sealed with a plastic screw cap, upon initial use, remove the plastic screw cap and replace it with the supplied pipette with cap. Draw up the drug into a pipette.

Squeeze the required number of drops of the drug onto the clean mucous membrane of the nasal passage, then pinch the nostril with your finger for a short time.

If the bottle is sealed with a dropper cap, carefully cut off the tip of the pipette, tightly close the pipette cap. Invert the bottle before use so that the liquid fills the entire space of the pipette. Remove the cap. Squeeze the required number of drops of the drug onto the clean mucous membrane of the nasal passage, then pinch the nostril with your finger for a short time. The instillation of the drug into the nasal passages is carried out in a sitting position with the head slightly thrown or tilted to one side, after which each nostril is clamped with a finger for a short time. The effectiveness of absorption may be reduced in the presence of increased secretions of the nasal mucosa, therefore, it is recommended to clear the nasal passage before use (instillation).

Dose: 2 drops in each nasal passage 3 times a day.

The duration of the course of the drug is 14 days. If necessary, the course of treatment can be repeated after 1-3 weeks, after consulting a doctor.

Use the drug only according to the method of administration and in the doses indicated in the instructions. If necessary, please consult your doctor before using this medication.

Side effect

With increased sensitivity to the perception of smell and taste, when the drug gets from the nasal cavity to the mucous membrane of the pharynx, unpleasant taste sensations may appear. Development of allergic reactions with individual intolerance is possible.

If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects that are not indicated in the instructions, inform your doctor.

Overdose

When using SelankЃ, no cases of overdose have been reported. Interaction with other medicinal products

SelankЃ does not affect the effects of drugs that depress and stimulate the central nervous system - haloperidol, pentobarbital, hexobarbital, analeptics. SelankЃ can be combined with any psychoactive and neuroactive therapy.

SelankЃ is safe when used together with ethanol-containing products.

If you are taking other medicines (including over-the-counter medicines), consult your doctor before using SelankЃ.

special instructions

SelankЃ does not cause drug dependence and addiction.

Influence on the ability to drive vehicles, mechanisms

Does not affect the ability to drive vehicles and use mechanisms.

Release form

Nasal drops, 3 ml in a glass bottle sealed with a plastic pipette stopper, or in a glass bottle sealed with a plastic screw cap with an attached pipette with a cap. Each bottle with instructions for use is packed in a cardboard box.

Storage conditions

Store in a dark place at a temperature not exceeding 10 ? C. Do not freeze. Store the opened bottle at a temperature not exceeding 25 ? — for no more than 15 days. Keep out of the reach of children.

Shelf life

2 years. Do not use after the expiration date.

Vacation conditions

Available without a prescription.