Salbutamol-Teva aerosol 100mkg / dose, 200 dose

Prevention and relief of bronchospasm in all forms of bronchial asthma. Reversible airway obstruction in chronic bronchitis and pulmonary emphysema, broncho-obstructive syndrome in children.

Threatening premature birth with uterine contractile activity; childbirth up to 37-38 weeks of pregnancy; isthmic-cervical insufficiency, a decrease in fetal heart rate depending on uterine contractions during periods of cervical dilatation and expulsion. For preventive purposes during operations on the pregnant uterus (the imposition of a circular suture in case of insufficiency of the internal pharynx of the uterus).

Inhalation

For relief of bronchospasm: 100 mcg (1 inhalation) 1-4 times a day. If necessary, the dose can be increased to 200 mcg (2 inhalations) 1Ц4 times a day.

For the prevention of bronchospasm: 100-200 mcg (1-2 inhalations) 15-30 minutes before physical activity or possible exposure to an allergen.

The maximum daily dose should not exceed 800 mcg (8 inhalations) during the day.

At least 4 hours should elapse between each dose taken.

Instructions for the patient on the use of the inhalation device

Before using the inhalation device for the first time, or if it has not been used for some time, it is necessary to check its serviceability by pressing the valve of the cartridge and releasing the dose of medication into the air.

1. Remove the protective cap from the inhalation device and ensure that the outlet tube of the inhalation device is clean. Hold the inhalation device between the index and thumb in an upright position, with the thumb on the bottom of the inhalation device, and the index finger on the dosing valve of the aluminum cylinder.

2. Shake the aluminum can vigorously up and down.

3. Take a deep breath through the mouth. Press the outlet tube of the inhalation device tightly with your lips.

4. Take a slow and deep breath. At the moment of inhalation, press the dosing valve of the balloon with your index finger, releasing a dose of Salbutamol-Teva, and continue to inhale slowly.

5. Remove the inhalation device from your mouth and hold your breath for 10 seconds or for a time that will not cause discomfort. Exhale slowly.

6. After inhalation, rinse your mouth with water, being careful not to swallow the aerosol that gets on the oral mucosa during inhalation.

7. If you need to enter more than one dose of the drug, wait 1 minute and repeat all steps from step 2 to step 6.

8. Close the inhalation device with a protective cap.

Take your time with steps 3 and 4. It is important to inhale as slowly as possible when the dose is released. Before use, you can practice in front of a mirror. If you notice 'steam' coming out of the top of the can or from the corners of your mouth, you should start over from step 2.

Cleaning the inhaler. The inhalation device should be cleaned at least once a week. Remove the aluminum can from the inhalation device. Gently rinse the inhalation device and protective cap with warm water. Do not use hot water! Shake the inhalation device and protective cap to remove water residues and dry them without using heating devices.

Do not allow the aluminum cylinder to come into contact with water!

Dosed inhalation aerosol

active substance: salbutamol sulfate 124 ?g (equivalent to 100 ?g salbutamol)

excipients: hydrofluoroalkane (HFA-134a) - 26.46 mg; ethanol - 3.42 mg

Threat of miscarriage in the first and second trimesters of pregnancy, premature placental abruption, bleeding or toxicosis in the third trimester of pregnancy; children under 2 years old; hypersensitivity to salbutamol. Application during pregnancy and lactation Salbutamol is contraindicated in case of a threat of miscarriage in the first and second trimesters of pregnancy, premature placental abruption, bleeding or toxicosis in the third trimester of pregnancy.

If it is necessary to use salbutamol during pregnancy, the expected benefits of treatment for the mother and the potential risk for the fetus should be weighed. Currently, there is insufficient data on the safety of the use of salbutamol in early pregnancy. Salbutamol is excreted in breast milk, therefore, if it is necessary to use it during lactation, the expected benefits of treatment for the mother and the possible risk for the child should also be assessed.

pharmachologic effect

Beta-adrenomimetic with a predominant effect on ?2-adrenergic receptors (localized, in particular, in the bronchi, myometrium, blood vessels). Prevents and relieves bronchospasm; reduces resistance in the airways, increases the vital capacity of the lungs. Prevents the release of histamine, a slow-reacting substance from mast cells and neutrophil chemotaxis factors. Compared with other drugs in this group, it has a less pronounced positive chrono- and inotropic effect on the myocardium. It causes expansion of the coronary arteries, practically does not reduce blood pressure. It has a tocolytic effect, lowering the tone and contractile activity of the myometrium.

Indications of the active substances of the drug Salbutamol

Prevention and relief of bronchospasm in all forms of bronchial asthma. Reversible airway obstruction in chronic bronchitis and pulmonary emphysema, broncho-obstructive syndrome in children.

Threatening premature birth with uterine contractile activity; childbirth up to 37-38 weeks of pregnancy; isthmic-cervical insufficiency, a decrease in fetal heart rate depending on uterine contractions during periods of cervical dilatation and expulsion. For preventive purposes during operations on the pregnant uterus (the imposition of a circular suture in case of insufficiency of the internal pharynx of the uterus).

Dosage regimen

Inside as a bronchodilator for adults and children over 12 years old - 2-4 mg 3-4 times / day, if necessary, the dose can be increased to 8 mg 4 times / day. Children aged 6-12 years - 2 mg 3-4 times / day; children 2-6 years old - 1-2 mg 3 times / day.

When administered by inhalation, the dose depends on the dosage form used, the frequency of use depends on the indications and the clinical situation.

As a tocolytic agent, intravenous drip is administered at a dose of 1-2 mg.

Side effect

From the side of the cardiovascular system: transient expansion of peripheral vessels, moderate tachycardia.

From the side of the central nervous system: headache, dizziness, nausea, vomiting.

From the side of metabolism: hypokalemia.

Allergic reactions: in isolated cases - angioedema, allergic reactions in the form of skin rash, urticaria, arterial hypotension, collapse.

Others: tremors of the hands, internal tremors, tension; rarely - paradoxical bronchospasm, muscle cramps.

Contraindications for use

Threat of miscarriage in the first and second trimesters of pregnancy, premature placental abruption, bleeding or toxicosis in the third trimester of pregnancy; children under 2 years old; hypersensitivity to salbutamol. Application during pregnancy and lactation Salbutamol is contraindicated in case of a threat of miscarriage in the first and second trimesters of pregnancy, premature placental abruption, bleeding or toxicosis in the third trimester of pregnancy.

If it is necessary to use salbutamol during pregnancy, the expected benefits of treatment for the mother and the potential risk for the fetus should be weighed. Currently, there is insufficient data on the safety of the use of salbutamol in early pregnancy. Salbutamol is excreted in breast milk, therefore, if it is necessary to use it during lactation, the expected benefits of treatment for the mother and the possible risk for the child should also be assessed.

Application in children

Contraindicated in children under 2 years of age.

special instructions

It is used with caution in tachyarrhythmias and other heart rhythm disorders, arterial hypertension, myocarditis, heart defects, aortic stenosis, diabetes mellitus, thyrotoxicosis, glaucoma, acute heart failure (subject to close medical supervision).

Increasing the dose or frequency of taking salbutamol should be supervised by a physician. Reducing the interval is possible only in exceptional cases and should be strictly justified.

When using salbutamol, there is a risk of hypokalemia, therefore, during the period of treatment in patients with severe bronchial asthma, the level of potassium in the blood should be monitored. The risk of hypokalemia increases with hypoxia.

Drug interactions

With the simultaneous use of salbutamol with noncardioselective beta-blockers, mutual suppression of therapeutic effects is possible; with theophylline - the risk of developing tachycardia and arrhythmia, in particular supraventricular extrasystole, increases.

With the simultaneous use of salbutamol and xanthine derivatives, corticosteroids or diuretics, the risk of hypokalemia increases.