Ronaxan 20 mg

DESCRIPTION

Ronaxan (Ronaxan) - a drug for the treatment of diseases of bacterial etiology in dogs and cats. Dosage form - tablets for oral administration. In appearance, the drug is a round biconvex tablets from light yellow to yellow.

COMPOSITION

Ronaxan is produced in two dosages containing doxycycline (in the form of hyclate) as an active ingredient - 20 mg / tab. and 100 mg / table, as well as auxiliary substances: magnesium stearate and microcrystalline cellulose.

PHARMACOLOGICAL PROPERTIES

Ronaxan belongs to the tetracycline group of antibacterial drugs.

Doxycycline hyclate, which is a part of the drug, belongs to the semisynthetic antibiotics of the third generation of the tetracycline group, is active against gram-positive and gram-negative microorganisms: Staphylococcus spp., Streptococcus spp., Corynebacterium spp., Actinomyces spp., Clostridisus spp., Clostridrix ., Listeria spp. Fusobacterium spp., Pseudomonas spp., Pasteurella spp., Eikenella spp., Enterococcus spp., Enterobacteria spp., Moraxella spp., Brucella spp., Bartonella spp., Proteus mirabilis, Escherichia coli, Citrobacter, Serramonella , as well as mycoplasmas, spirochetes, chlamydia and rickettsia.

The mechanism of the bacteriostatic action of doxycycline is associated with inhibition of enzymes that catalyze the binding of aminoacetyl RNA to ribosomal acceptors, which leads to blocking of the interaction of aminoacyltransport RNA with the 30S subunit of the ribosomal membrane and disruption of microbial cell protein synthesis.

After oral administration of the drug, doxycycline hyclate is easily absorbed in the gastrointestinal tract and reaches the systemic circulation, the maximum plasma concentration is observed 3 hours after administration, remaining at a therapeutic level for 24 hours; easily penetrates into most organs and tissues, is metabolized in the liver with the formation of inactive metabolites, and is excreted from the body mainly with feces and urine.

According to the degree of its effect on the body, Ronaxan is classified as a moderately hazardous substance (hazard class 3 according to GOST 12.1.007-76), in the recommended doses it does not have a sensitizing, teratogenic and embryotoxic effect.

PURPOSE

Ronaxan is prescribed to cats and dogs with a therapeutic purpose for diseases of the respiratory system (rhinitis, tonsillitis, bronchopneumonia), the genitourinary system (cystitis, pyelonephritis, prostatitis, endometritis), skin (purulent dermatitis, abscesses) and other infections, the causative agents of which are sensitive to doxycycline.

DOSAGE AND APPLICATION

Ronaxan is administered to animals individually orally in a mixture with food or is injected forcibly onto the root of the tongue once a day at a dose of 10 mg doxycycline per 1 kg of animal weight. The course of treatment for the acute course of the disease is 3-5 days, for the chronic one - 8-10 days.

As prescribed by a veterinarian, the dosage and duration of use can be increased.

SPECIAL INSTRUCTIONS

In case of an overdose of Ronaxan, the animal may experience vomiting, refusal to feed, and impaired coordination of movement. In this case, you should stop using the drug and prescribe symptomatic therapy.

The peculiarities of the action of the drug during its first use and withdrawal were not revealed.

For pregnant and lactating females, Ronaxan is used for health reasons under the supervision of the attending veterinarian, since with systemic absorption, the drug can cause disorders in the development of fetal bone tissue.

Avoid skipping the next dose of the drug, as this can lead to a decrease in therapeutic effectiveness. If one dose is missed, the use of the drug is resumed in the same dose according to the same scheme.

With increased individual sensitivity to tetracyclines and the occurrence of allergic reactions, the drug is discontinued and antihistamines and symptomatic therapy are prescribed to the animal.

Ronaxan should not be used in conjunction with bactericidal antibiotics of the penicillin and cephalosporin groups (due to a possible decrease in antibacterial activity), with medicines and feed additives containing calcium, magnesium, iron and aluminum salts, barbiturates and phenytoin (due to a possible deterioration in absorption).

Ronaxan is not intended for use in productive animals.

CONTRAINDICATIONS

Contraindication to use is an increased sensitivity of the animal to the components of the drug and antibiotics of the tetracycline group, pronounced impaired liver and / or kidney function.

Ronaxan should not be used in pregnant and lactating females, as well as in puppies and kittens during the period of dental development.

SIDE EFFECTS

When using the drug in accordance with this instruction, side effects and complications in animals, as a rule, are not observed.

SHELF LIFE AND STORAGE

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 36 months from the date of production.

Do not use Ronaxan after the expiration date.

Store the medicinal product in the manufacturer's sealed packaging, separately from food and feed, in a place protected from direct sunlight, at a temperature from 0 В° C to 25 В° C, out of the reach of children.

PACKAGING

Ronaxan is produced packaged in 10 tablets in blisters made of polyvinyl chloride and aluminum foil on a paper basis. Blisters are packed in cardboard boxes by the piece, 2 pieces (for a dosage of 20 mg / tab.) Together with instructions for use.

Specifications

KolVUP

1

Manufacturer

Merial

Teaser

for the treatment of diseases of bacterial etiology in dogs and cats