Rinikold tab. No. 10

Release form, composition and packaging

Tablets 1 tab.

paracetamol 500 mg

caffeine 30 mg

phenylephrine hydrochloride 10 mg

chlorphenamine maleate 2 mg

microcrystalline cellulose, starch, magnesium stearate, talc, sodium starch glycolate, gelatin, polyvinylpyrrolidone, methylparaben, propylparaben

10 pieces.

- blisters (1) - cardboard packs.

10 pieces.

- blisters (2) - cardboard packs.

10 pieces.

- blisters (3) - cardboard packs.

10 pieces.

- blisters (4) - cardboard packs.

10 pieces.

- strips (1) - cardboard packs.

10 pieces.

- strips (2) - cardboard packs.

10 pieces.

- strips (3) - cardboard packs.

10 pieces.

- strips (4) - cardboard packs.

pharmachologic effect

Combined drug used for colds.

Paracetamol has antipyretic and analgesic effects.

Phenylephrine has a vasoconstrictor effect, helping to relieve nasal congestion and reduce nasal discharge.

Chlorphenamine has antiallergic and decongestant effects.

Reduces vascular permeability, eliminates swelling and hyperemia of the nasal mucosa, suppresses the symptoms of allergic rhinitis, making breathing easier.

Caffeine has a stimulating effect on the central nervous system, which leads to a decrease in fatigue and drowsiness, and an increase in mental and physical performance.

Pharmacokinetics

Data on the pharmacokinetics of Rinikold are not provided.

Indications for use

colds accompanied by rhinitis, nasal congestion, headache, fever, chills, pain in joints, muscles.

Contraindications for use

pregnancy

lactation period (breastfeeding)

children under 6 years old

concomitant use of tricyclic antidepressants, MAO inhibitors, beta-blockers

simultaneous administration of other drugs containing active substances that make up Rinikold

hypersensitivity to drug components.

The drug should be prescribed with caution in case of glucose-6-phosphate dehydrogenase deficiency, blood diseases, renal and / or liver failure, angle-closure glaucoma, prostate adenoma, Gilbert's syndrome, arterial hypertension, thyroid diseases, diabetes mellitus, bronchial asthma.

Dosage regimen

The drug is administered orally

Adults - 1-2 tab.

every 4-6 hours. The maximum daily dose is 8 tab.

Children over 6 years old - 1 tab.

every 4-6 hours, but no more than 4 times / day for no more than 5 days.

Overdose

Symptoms are mainly due to the action of paracetamol: pallor of the skin, anorexia, nausea, vomiting, hepatonecrosis, increased activity of hepatic transaminases, and an increase in prothrombin time are possible.

Treatment: gastric lavage followed by the appointment of activated charcoal, symptomatic therapy

The patient should be warned about the need to consult a doctor in case of overdose.

Side effect

From the side of the central nervous system: dizziness, sleep disturbances, hyperexcitability, headache

From the digestive system: nausea, dry mouth

Others: allergic reactions.

When taking the drug in the recommended doses, side effects are rare.

Drug interactions

The drug enhances the effect of sedatives, ethanol

Combined use with antidepressants, antiparkinsonian drugs, antipsychotics, phenothiazine derivatives (chlorpromazine, trifluoperazine, levomepromazine) increases the risk of urinary retention, dry mouth, constipation.

With simultaneous use with GCS, the risk of developing glaucoma increases.

Chlorphenamine when used simultaneously with MAO inhibitors, furazolidone can lead to hypertensive crisis, agitation

Tricyclic antidepressants enhance the sympathomimetic effect of the drug, the simultaneous administration of halothane increases the risk of ventricular arrhythmia.

Reduces the hypotensive effect of guanethidine, which

Structure

Active ingredients: paracetamol 500 mg

caffeine 30 mg

phenylephrine hydrochloride 10 mg

chlorpheniramine maleate 2 mg

Excipients: MCC

starch

magnesium stearate

talc

sodium starch glycolate

gelatin

polyvinylpyrrolidone

methylparaben

propylparaben.

INN / Active ingredient

phenylephrine hydrochloride, chlorphenamine maleate, paracetamol, caffeine

Storage conditions and periods

In a dry place, at a temperature not exceeding 25 degrees.

Specifications

Category

Pain and fever

Scope of the drug

General

Dosage (volume) of the substance in the preparation

paracetamol 500 mg

Release form

Tablet

Manufacturer country

India

Package quantity, pcs

ten

Minimum age from

6 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Shreya Life Sciences

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Dosage form

Pills

A type

Medicine

Expiration date in days

1095

Package weight, g

15

Mode of application

:

The drug is prescribed inside < br> Adults - 1-2 tablets every 4-6 hours. The maximum daily dose - 8 tablets < br> Children over 6 years old - 1 tablet every 4-6 hours, but not more than 4 times / day in within no more than 5 days.

Pharmaco-therapeutic group

:

ARI and cold" symptoms remedy (analgesic non-narcotic drug + psychostimulant + alpha-adrenergic agonist + H1-histamine receptor blocker)

Anatomical and therapeutic characteristics

:

R05X Preparations for the elimination of cold symptoms in combination with others

Information on technical characteristics, delivery set, country of manufacture "