Rhodotium 45% granules 1kg

DESCRIPTION

Rhodotium 45% is an antibacterial drug for the treatment of chickens and turkeys: for mycoplasma infections caused by Mycoplasma gallisepticum, Mycoplasma synovia and Mycoplasma meleagridis, pigs for respiratory and gastrointestinal diseases of bacterial etiology, the pathogens of which are sensitive to tiamulin, as well as.

COMPOSITION

Contains 450 mg of tiamulin hydrogen fumarate as an active ingredient in 1 g, as well as auxiliary components - lactose monohydrate and povidone. It is a granules from white to pale yellow color with a slight specific odor, soluble in water.

PHARMACOLOGICAL PROPERTIES

Tiamulin, which is part of Rodotium 45%, belongs to the semisynthetic derivatives of the diterpene antibiotic pleuromutilin. The drug is active against gram-positive (Staphylococcus spp., Streptococcus spp., Clostridium spp., Corynebacterium spp., Erysipelothrix spp., Listeria spp.) And gram-negative (Pasteurella spp., Klebsiella pneumoniae., Actinobacterium spp. , Bacteroides spp., Lawsonia intracellularis) of microorganisms, mycoplasmas (Mycoplasma hyopneumoniae, M. hyorhinis, M. hyosynoviae, M. synoviae, M. gallisepticum, M. meleagridis), as well as brachyspira (Brachyspira hyodysenteriae, Br. Innoceicoli , Br. Suis). The mechanism of the bacteriostatic action of tiamulin is to suppress protein synthesis in the microbial cell at the ribosomal level.

The maximum concentration of the antibiotic in the body of the bird is found in 4 hours, and in the body of pigs in 2 hours after the administration of the drug. Tiamulin is metabolized in the liver and excreted from the body mainly in the bile and partially in the urine. Rhodotium 45% in terms of the degree of impact on the body of warm-blooded animals refers to low-hazard substances, in recommended doses does not have a local irritating and resorptive-toxic effect.

INDICATIONS

Assign to pigs - with a therapeutic purpose for dysentery, enzootic pneumonia and mycoplasma arthritis; chickens and turkeys - for therapeutic and therapeutic purposes in case of mycoplasma infections caused by Mycoplasma gallisepticum, Mycoplasma synovia and Mycoplasma meleagridis.

APPLICATION

Rhodotium 45% is used with water for individual or group drinking. During the period of medical and therapeutic-prophylactic treatments, the medicinal solution of tiamulin should be the only source of drinking water for pigs and birds. A fresh solution of the drug must be prepared daily.

For the treatment of dysentery in pigs, the drug is used at a dose of 0.02 g per 1 kg of animal weight, which corresponds to 8.8 mg / kg of tiamulin. The daily intake of the animals is ensured by drinking 0.006% tiamulin solution for 3-5 days.

For the treatment of enzootic pneumonia of pigs, Rhodotium 45% is used at a dose of 0.033-0.045g (15-20mg of tiamulin) per 1kg of animal weight. The daily intake of animals is ensured by drinking a 0.012-0.018% tiamulin solution for 5-10 days.

For the treatment of swine pleuropneumonia, the drug is used at a dose of 0.045 g (20 mg of tiamulin) per 1 kg of animal weight. The daily intake of the animals is ensured by drinking 0.018% tiamulin solution for 5-7 days.

Before use, the daily rate of water consumption by pigs is calculated and a medicinal solution of the required concentration is prepared.

To prepare a 0.006% solution of tiamulin (DV), 1 g of Rhodotium granules 45% is dissolved in 7.5 l of water; To prepare a 0.012% solution - 1 g of granules is dissolved in 3.75 l of water; To prepare a 0.018% solution, 1 g of granules is dissolved in 2.5 l of water.

For therapeutic and therapeutic purposes in case of mycoplasma infections, broiler chickens, replacement chickens up to 16 weeks of age and parent stock, Rodotium 45% is used at a dose of 0.067-0.11 g per 1 kg of bird weight, which corresponds to 30-50 mg / kg of tiamulin. The bird's daily dose is ensured by drinking 0.025% tiamulin solution for 3-5 days. To prepare a 0.025% solution of tiamulin, 1.1 g of the drug is dissolved in 2 liters of water.

For therapeutic and therapeutic purposes in turkeys with mycoplasma infections, the drug is used at a dose of 0.056-0.11 g per 1 kg of bird weight, which corresponds to 25-50 mg / kg of tiamulin. The bird's daily dose is ensured by drinking 0.025% tiamulin solution for 3-5 days. To prepare a 0.025% solution of tiamulin, 1.1 g of the drug is dissolved in 2 liters of water.

SPECIAL INSTRUCTIONS

Slaughter of pigs for meat is allowed after 7 days, chickens - after 3 days, turkeys - 4 days after stopping the use of the drug. Meat of pigs and poultry, who were forcedly killed before the established deadlines, can be used for the production of meat and bone meal or as feed for animals.

SIDE EFFECTS

Allergic reactions are possible in animals hypersensitive to tiamulin. With proper use and dosage, side effects are usually not observed.

CONTRAINDICATIONS

It is forbidden to use Rhodotium 45% for laying hens whose eggs are intended for food purposes, as well as for replacement hens from 16 weeks of age, due to the accumulation of tiamulin in eggs. It should not be administered to animals with impaired renal and hepatic function, as well as with increased individual sensitivity to tiamulin. Rhodotium 45% is not recommended to be used simultaneously, as well as 7 days before and 7 days after the use of ionophore coccidiostatics (monensin, salinomycin, maduramycin and narasin), as well as aminoglycoside antibiotics due to the possible occurrence of side effects and complications in animals (diarrhea, anorexia, paresis, nephrotoxic effects).

PRECAUTIONS

All work with the drug must be carried out using overalls and personal protective equipment (rubber gloves, goggles, respirator). Do not smoke, drink or eat while working. At the end of work, wash your face and hands thoroughly with soap, rinse your mouth with water.

STORAGE

With precautions according to list B. In the manufacturer's packaging in a dry, protected from direct sunlight and out of reach of children and animals. Separated from food and feed at temperatures from 0 to 25 В° C. Shelf life is 2 years.

PACKING

The drug is produced packaged in 1 kg polypropylene packages of appropriate capacity.

Specifications

KolVUP

five

Manufacturer

Huvepharma

Temperature regime

from 0 to +25

Teaser

antibacterial drug based on tiamulin for the prevention and treatment of pigs with dysentery, enterocolitis of spirochete etiology, enzootic bronchorneumonia