Retinoic ointment 0.05%, 15 g

Acne vulgaris, seborrheic dermatitis, rosacea, perioral dermatitis.

The ointment is applied in a thin layer to the affected skin twice a day.

The duration of treatment is 4-12 weeks.

A second course of treatment is possible after consulting a doctor.

Active ingredient: isotretinoin 0.05 or 0.1 g.

Excipients: butylhydroxytoluene - 0.05 g, butylhydroxyanisole - 0.025 g, emulsion wax - 8.0 g, liquid paraffin - 8.0 g, glycerol (glycerin) - 10.0 g, ethanol (ethyl alcohol) 95% - 10 , 0 g, purified water up to 100 g.

Use with caution in chronic liver disease, kidney disease, chronic pancreatitis, cardiac decompensation.

Trade name:

Retinoic ointment

International non-proprietary name:

isotretinoin

Dosage form:

ointment for external use.

Composition:

Active ingredient: isotretinoin 0.05 or 0.1 g.

Excipients: butylhydroxytoluene - 0.05 g, butylhydroxyanisole - 0.025 g, emulsion wax - 8.0 g, liquid paraffin - 8.0 g, glycerol (glycerin) - 10.0 g, ethanol (ethyl alcohol) 95% - 10 , 0 g, purified water up to 100 g.

Description:

homogeneous ointment from light yellow to yellow.

Pharmacotherapeutic group:

tissue regeneration stimulant.

ATX code:

(D10AD04)

Pharmacological properties

Isotretinoin is one of the biologically active forms of vitamin A. It inhibits the terminal differentiation of sebocytes and hyperproliferation of the epithelium of the excretory ducts of the sebaceous glands, normalizes the composition of their secretions and facilitates its evacuation. This reduces the production of sebum and reduces the inflammatory response around the glands. The ointment has an antiseborrheic, anti-inflammatory, keratolytic effect, enhances the regeneration processes in the skin.

Indications for use

Acne vulgaris, seborrheic dermatitis, rosacea, perioral dermatitis.

Contraindications

Use with caution in chronic liver disease, kidney disease, chronic pancreatitis, cardiac decompensation.

Pregnancy and lactation

Not recommended for use on large areas of skin during pregnancy, breastfeeding and women planning a pregnancy.

Method of administration and dosage

The ointment is applied in a thin layer to the affected skin twice a day.

The duration of treatment is 4-12 weeks.

A second course of treatment is possible after consulting a doctor.

Side effect

In the second week of treatment, an exacerbation reaction is possible - the appearance of new rashes, itching, redness and peeling of the skin. In case of a pronounced reaction, it is recommended to stop treatment for several days before it subsides. In some cases, with individual sensitivity on the first - second day of use, maculopapular rashes, itching and swelling appear. In such cases, the drug should be discontinued. With prolonged use, the development of symptoms of chronic hypervitaminosis A (cheilitis, conjunctivitis, dryness and peeling of the skin) is possible.

Interaction with other medicinal products

The ointment should not be prescribed to patients receiving other drugs from the retinoid group in order to reduce the risk of hypervitaminosis A. The effect of the ointment is weakened with the simultaneous local use of glucocorticosteroids.

special instructions

It is not recommended to apply the ointment to the skin around the eyes, as well as in severe acute inflammation. Cannot be applied to mucous membranes. During treatment, you should avoid exposure to the sun, if necessary, resort to the use of sunscreens, prophylactic and therapeutic use of ultraviolet rays and a visit to the solarium are not recommended.

The drug does not affect the ability to drive and perform work that requires increased concentration.

Release form

Ointment for external use 0.05% and 0.1%.

Aluminum tubes of 10, 15, 20 and 35 g.

The tube, together with the instructions for use, is placed in a cardboard box.

Storage conditions

At a temperature of 2 to 8 ? C.

Avoid freezing.

Keep out of the reach of children.

Shelf life

2 years. Do not use after the expiration date.

Conditions of dispensing from pharmacies

Without recipe.