Retasol solution for external use 0.025%, 50ml

In adults and adolescents over 11 years old, papulopustular and comedonal forms of acne vulgaris, rosacea (with a small number of rashes), perioral dermatitis, mild seborrheic dermatitis. After the withdrawal of retinoids administered orally or rectally, it is possible to use the drug Retasol in order to maintain the achieved clinical effect.

In adults and adolescents over 11 years old, papulopustular and comedonal forms of acne vulgaris, rosacea (with a small number of rashes), perioral dermatitis, mild seborrheic dermatitis. After the withdrawal of retinoids administered orally or rectally, it is possible to use the drug Retasol in order to maintain the achieved clinical effect.

Active ingredient: isotretinoin 0.25 mg
Excipients: butyl hydroxytoluene, butyl hydroxyanisole, propylene glycol, ethanol (ethyl alcohol) 95% up to 1 ml.

Individual hypersensitivity to the components of the drug, children under 11 years of age. Use with caution in chronic liver disease, kidney disease, chronic pancreatitis, cardiac decompensation.

Pregnancy and lactation
Contraindicated during pregnancy, lactation and women planning pregnancy.

Trade name: RetasolЃ

INN or Generic Name: Isotretinoin.

Dosage form:

solution for external use.

Composition:

Active ingredient: isotretinoin 0.25 mg
Excipients: butyl hydroxytoluene, butyl hydroxyanisole, propylene glycol, ethanol (ethyl alcohol) 95% up to 1 ml.

Description: transparent oily liquid from light yellow to yellow color with a slight specific smell of ethanol.

Pharmacological group: acne treatment

ATX code: (D10A01)

Pharmacological properties
Isotretinoin is one of the biologically active forms of vitamin A. It inhibits the terminal differentiation of sebocytes, hyperproliferation of the epithelium of the excretory ducts of the sebaceous glands, normalizes the composition of their secretions and facilitates its evacuation.
Due to this, the production of sebum decreases, its secretion is facilitated, the composition is normalized, and the inflammatory reaction around the glands decreases. The solution has an antiseborrheic, anti-inflammatory, keratolytic effect; enhances the regeneration processes in the skin.

Indications for use
In adults and adolescents over 11 years old, papulopustular and comedonal forms of acne vulgaris, rosacea (with a small number of rashes), perioral dermatitis, mild seborrheic dermatitis. After the withdrawal of retinoids administered orally or rectally, it is possible to use the drug Retasol in order to maintain the achieved clinical effect.

Contraindications
Increased individual sensitivity to the components of the drug. Use with caution in chronic liver disease, kidney disease, chronic pancreatitis, cardiac decompensation.

Pregnancy and lactation
Contraindicated during pregnancy, lactation and women planning pregnancy.

Method of administration and dosage
The solution is applied with a cotton swab on previously cleansed skin (after washing or wiping with a tonic that does not contain alcohol) 2 times a day. The duration of treatment is 4-12 weeks. A second course of treatment is possible after consulting a doctor.

Side effects
In the first week of treatment, an exacerbation reaction may occur - the appearance of new rashes, itching, swelling, redness and peeling of the skin. With a pronounced reaction, it is recommended to stop treatment for several days before it subsides. In some cases, intolerance to the drug is observed - on the first or second day of use, maculopapular rashes, itching and swelling appear. In such cases, you should discontinue the drug and consult a doctor.

Overdose
With prolonged use, overdose phenomena are possible: redness and peeling of the skin at the sites of application of the drug, cheilitis. Overdose phenomena quickly disappear after discontinuation of the drug and the use of local glucocorticosteroids.

Interaction with other medicinal products
The solution should not be administered to patients receiving other drugs from the group of reginoids in order to reduce the risk of hypervitaminosis A. The effect of the solution is weakened with the simultaneous administration of antibiotics of the tetracycline group, as well as with local application of glucocorticosteroids.

Special instructions
It is not recommended to apply the solution to the skin around the eyes, as well as in severe acute inflammation. Cannot be applied to mucous membranes.

Release form
Solution for external use 0.025% 10, 15, 20, 30 and 50 ml in orange glass vials. Each bottle, along with instructions for medical use, is placed in a cardboard box.

Storage conditions
In a dark place at a temperature not exceeding 22 ? C, out of reach of children.

Shelf life is
2 years. Do not use after the expiration date.

Terms of dispensing from pharmacies
Without prescription.