Relief Advance rectal ointment with applicator, 28.4 g

As a local analgesic:

• hemorrhoids;

• cracks in the anus;

• after proctological operations;

• when carrying out diagnostic manipulations.

The drug should be used after hygiene procedures.

Remove the protective cap from the applicator. Attach the applicator to the tube and squeeze out a small amount of ointment to lubricate the applicator. The ointment is carefully applied through the applicator to the affected areas outside or inside the anus up to 4 times / day in the morning, evening and after each bowel movement for 7-10 days.

After each use, rinse the applicator thoroughly and place it in a protective cap.

Children under 12 years of age: the drug should only be used as directed by a doctor.

If after treatment there is no improvement or the symptoms worsen, or new symptoms appear, the patient should consult a doctor.

The drug should be used in accordance with the indications and the indicated dosage regimen.

Active ingredient: benzocaine 200 mg / g (20%).

Excipients: shark liver oil 30 mg / g (3%), mineral oil 120 mg / g (12%), petrolatum 617 mg / g (61.7%), propylene glycol 20 mg / g (2%), methyl parahydroxybenzoate 2 , 4 mg / g (0.24%), propyl parahydroxybenzoate 0.6 mg / g (0.06%), sorbitan monostearate 10 mg / g (1%).

• thromboembolism;

• granulocytopenia;

• hypersensitivity to the components of the drug.

Trade name of the drug

ReliefЃ Advance

International non-proprietary name

Benzocaine

Dosage form

Ointment for rectal and external use

Composition

Active ingredient: benzocaine 200 mg / g (20%).

Excipients: shark liver oil 30 mg / g (3%), mineral oil 120 mg / g (12%), petrolatum 617 mg / g (61.7%), propylene glycol 20 mg / g (2%), methyl parahydroxybenzoate 2 , 4 mg / g (0.24%), propyl parahydroxybenzoate 0.6 mg / g (0.06%), sorbitan monostearate 10 mg / g (1%).

Description

Homogeneous white ointment with a yellowish tinge, with a weak characteristic odor, free of foreign inclusions.

Clinical and pharmacological group: A drug with anti-inflammatory, wound healing and local anesthetic action for local use in proctology

Pharmaco-therapeutic group: Local anesthetic

pharmachologic effect

Antihemorrhoidal drug.

Benzocaine is a local anesthetic that does not have a resorptive effect.

Pharmacokinetics

Data on the pharmacokinetics of ReliefЃ Advance are not provided.

Indications

As a local analgesic:

• hemorrhoids;

• cracks in the anus;

• after proctological operations;

• when carrying out diagnostic manipulations.

Dosage regimen

The drug should be used after hygiene procedures.

Remove the protective cap from the applicator. Attach the applicator to the tube and squeeze out a small amount of ointment to lubricate the applicator. The ointment is carefully applied through the applicator to the affected areas outside or inside the anus up to 4 times / day in the morning, evening and after each bowel movement for 7-10 days.

After each use, rinse the applicator thoroughly and place it in a protective cap.

Children under 12 years of age: the drug should only be used as directed by a doctor.

If after treatment there is no improvement or the symptoms worsen, or new symptoms appear, the patient should consult a doctor.

The drug should be used in accordance with the indications and the indicated dosage regimen.

Side effect

The following adverse reactions have been reported with the use of drugs containing benzocaine under various conditions. Since these reactions are given in reference materials, or voluntarily come from the population in an undetermined amount, it is not always possible to reliably estimate their frequency or establish a causal relationship when using the drug.

From the immune system: allergic reactions.

From the hematopoietic system: methemoglobinemia.

On the part of the skin and subcutaneous tissues: allergic dermatitis.

General and local reactions: erythema, local irritation, edema, pain, rash at the site of application.

If the patient notes other side effects, the doctor should be informed.

Contraindications for use

• thromboembolism;

• granulocytopenia;

• hypersensitivity to the components of the drug.

Application during pregnancy and lactation

ReliefЃ Advance is used during pregnancy and lactation (breastfeeding) with caution, in cases where the expected benefit to the mother outweighs the potential risk to the fetus or child.

Application in children

The question of prescribing the drug Relief Advance for children under the age of 12 should be decided individually, depending on the clinical situation.

special instructions

In case of profuse bloody discharge from the rectum or if painful symptoms persist for more than 7 days, it is necessary to additionally consult a proctologist.

There are reports that products containing benzocaine can cause methemoglobinemia. Symptoms such as cyanosis of the skin, lips and nails, headache, dizziness, shortness of breath (difficulty breathing), weakness, tachycardia that occur during treatment may indicate a potentially life-threatening methemoglobinemia that requires immediate medical attention.

In order to minimize systemic side effects, do not exceed the recommended daily dose, unless otherwise directed by your doctor.

It is not recommended to use the drug on damaged skin, because it may increase systemic absorption.

Contact of the drug with latex products (contraceptive diaphragms and condoms) should be avoided to avoid reducing their effectiveness.

Influence on the ability to drive vehicles and mechanisms

Does not affect.

Overdose

Possible symptoms can be associated with systemic absorption of benzocaine, which is part of the drug, and include drowsiness, anxiety, agitation; in severe cases, convulsions; extremely rarely - methemoglobinemia (manifested by respiratory disorders and cyanosis).

With a significant excess of the recommended single and daily doses of shark liver oil included in the preparation, a tendency to increased blood coagulation may develop.

Treatment: with methemoglobinemia - intravenous administration of methylene blue.

Drug interactions

The drug interaction of the drug ReliefЃ Advance is not described.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25 ? C.

Shelf life

Shelf life is 2 years.

Terms of sale

The drug is dispensed without a prescription.

Contacts for inquiries

BAYER AG (Germany)