Pyrantel | Pyrantel tablets 250 mg, 3 pcs.
Special Price
$11.04
Regular Price
$21.00
In stock
SKU
BID494442
Latin name
Pyrantel
Pyrantel
Latin name
Pyrantel
Packing
3 pcs
Pharmacological action
Pyrantel - anthelmintic.
Blocks neuromuscular transmission in sensitive helminths.
Pharmacodynamics
Acts on helminths in the early phase of development and on mature forms, does not affect larvae in the migration stage. Active against Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Trichostrongylus orientalis, Trichostrongylus colubriformis.
Pharmacokinetics
Practically not absorbed in the digestive tract. After oral administration in a single dose of 10 mg / kg body weight, Cmax is 0.005–0.13 μg / ml and is achieved within 1-3 hours. It is partially metabolized in the liver to N-methyl-1,3-propanediamine. It is excreted with feces (50% of the dose taken - unchanged) and with urine (about 7% - unchanged and as a metabolite).
Indications
Enterobiosis, ascariasis, hookworm infection, necatorosis.
Contraindications
Hypersensitivity.
Use during pregnancy and lactation
Pyrantel is contraindicated in pregnancy.
If necessary, use during lactation should decide on the termination of breastfeeding.
Composition of
1 tablet contains:
Active ingredient: pyrantel 250 mg
Excipients: starch, gelatin, acacia gum, methyl parahydroxybenzoate, propyl parahydroxybenzoate, sodium carboxymethyl starch magnesium, starch, magnesium, starch.
Dosage and Administration
Inside. The dose and frequency of administration are set individually, depending on the indications, age and body weight of the patient.
In case of ascariasis and enterobiasis, it is prescribed once at the rate of 10 mg / kg: for adults and children over 12 years old - 750 mg (for body weight over 75 kg - 1 g) for children from 6 months to 2 years old - 125 mg, 2-6 years old - 250 mg, 6-12 years - 500 mg. In order to avoid self-invasion, it is recommended that the course be repeated 3 weeks after the first dose.
With hookworm infection - 10 mg / kg in 1 dose for 3 days.
In case of necatorosis (severe forms) - 20 mg / kg / day for 2 days.
With isolated ascariasis, 5 mg / kg once.
Chew tablets before swallowing.
Side effects
From the nervous system and sensory organs: rarely - headache, dizziness, drowsiness, insomnia, weakness in some cases - hearing impairment, hallucinations, confusion, paresthesia.
From the digestive tract: nausea, vomiting, diarrhea, stomach pain rarely - increased activity of hepatic transaminases.
Other: skin rash, fever.
Storage Conditions
In a dark place, at a temperature of 15-25 РC.
Term hodnosty
3 years
Active substance
Pyrantel
Terms leave through pharmacies
In retseptu
lekarstvennaja form
tablets
Pyrantel
Packing
3 pcs
Pharmacological action
Pyrantel - anthelmintic.
Blocks neuromuscular transmission in sensitive helminths.
Pharmacodynamics
Acts on helminths in the early phase of development and on mature forms, does not affect larvae in the migration stage. Active against Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Trichostrongylus orientalis, Trichostrongylus colubriformis.
Pharmacokinetics
Practically not absorbed in the digestive tract. After oral administration in a single dose of 10 mg / kg body weight, Cmax is 0.005–0.13 μg / ml and is achieved within 1-3 hours. It is partially metabolized in the liver to N-methyl-1,3-propanediamine. It is excreted with feces (50% of the dose taken - unchanged) and with urine (about 7% - unchanged and as a metabolite).
Indications
Enterobiosis, ascariasis, hookworm infection, necatorosis.
Contraindications
Hypersensitivity.
Use during pregnancy and lactation
Pyrantel is contraindicated in pregnancy.
If necessary, use during lactation should decide on the termination of breastfeeding.
Composition of
1 tablet contains:
Active ingredient: pyrantel 250 mg
Excipients: starch, gelatin, acacia gum, methyl parahydroxybenzoate, propyl parahydroxybenzoate, sodium carboxymethyl starch magnesium, starch, magnesium, starch.
Dosage and Administration
Inside. The dose and frequency of administration are set individually, depending on the indications, age and body weight of the patient.
In case of ascariasis and enterobiasis, it is prescribed once at the rate of 10 mg / kg: for adults and children over 12 years old - 750 mg (for body weight over 75 kg - 1 g) for children from 6 months to 2 years old - 125 mg, 2-6 years old - 250 mg, 6-12 years - 500 mg. In order to avoid self-invasion, it is recommended that the course be repeated 3 weeks after the first dose.
With hookworm infection - 10 mg / kg in 1 dose for 3 days.
In case of necatorosis (severe forms) - 20 mg / kg / day for 2 days.
With isolated ascariasis, 5 mg / kg once.
Chew tablets before swallowing.
Side effects
From the nervous system and sensory organs: rarely - headache, dizziness, drowsiness, insomnia, weakness in some cases - hearing impairment, hallucinations, confusion, paresthesia.
From the digestive tract: nausea, vomiting, diarrhea, stomach pain rarely - increased activity of hepatic transaminases.
Other: skin rash, fever.
Storage Conditions
In a dark place, at a temperature of 15-25 РC.
Term hodnosty
3 years
Active substance
Pyrantel
Terms leave through pharmacies
In retseptu
lekarstvennaja form
tablets
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