Pulmicort Turbuhaler powder 100mkg / dose, 200 dose

bronchial asthma, requiring maintenance therapy with corticosteroids to control the inflammatory process;

chronic obstructive pulmonary disease (COPD).

Inhalation The dose is selected individually. The recommended doses of the drug in case of initiation of inhaled glucocorticoid therapy during severe exacerbations of bronchial asthma, as well as against the background of dose reduction or cancellation of oral corticosteroids, are as follows:

Children over 6 years old - 100-800 mcg / day (the total daily dose can be divided into 2-4 inhalations). If the recommended dose does not exceed 400 mcg / day, the entire dose of the drug can be taken at one time (at a time).

In children, the transition to a single dose of the drug should be carried out under the supervision of a pediatrician.

Adults - the usual dose is 200-800 mcg / day (the total daily dose can be divided into 2-4 inhalations). For the treatment of severe exacerbation of bronchial asthma, the daily dose can be increased to 1600 mcg.

If the recommended dose does not exceed 400 mcg / day, the entire dose of the drug can be taken at one time (at a time).

When selecting a maintenance dose, it is necessary to strive for the appointment of the minimum effective dose.

The onset of the therapeutic effect after inhalation of 1 dose is several hours. The maximum therapeutic effect is achieved within 1Ц2 weeks after treatment. PulmicortЃ TurbuhalerЃ has a prophylactic effect on the course of bronchial asthma and does not affect the acute manifestations of the disease.

Better efficacy of budesonide was demonstrated when using TurbuhalerЃ compared to a similar dose of budesonide in the form of a metered-dose aerosol. In case of transfer of a patient in stable condition from PulmicortЃ in aerosol form to PulmicortЃ TurbuhalerЃ, the possibility of reducing the daily dose of budesonide should be considered.

To enhance the therapeutic effect, it is possible to recommend an increase in the daily dose of PulmicortЃ TurbuhaleraЃ instead of a combination of the drug with oral corticosteroids, due to the lower risk of developing systemic effects.

Patients receiving oral corticosteroids

Cancellation of oral corticosteroids should be carried out against the background of a stable state of health of the patient. Within 10 days, it is recommended to take a high dose of PulmicortЃ while taking oral corticosteroids in a selected dose. In the future, the dose of oral corticosteroids should be gradually reduced (for example, 2.5 mg of prednisolone or its analogue) to the lowest possible level. In many cases, it is possible to completely abandon the intake of oral corticosteroids.

There is no data on the use of budesonide in patients with renal insufficiency or impaired liver function. Taking into account the excretion of budesonide due to biotransformation in the liver, an increase in the duration of the drug's action in patients with severe liver cirrhosis can be expected.

hypersensitivity to budesonide;

children under 6 years of age.

With caution: in the treatment of inhaled corticosteroids in patients with active or inactive forms of pulmonary tuberculosis, fungal, viral or bacterial respiratory infections.