Protargol-ENT 0.2 N1 tablets for solution for topical application + bottle + cap, pipette

Dosage form

Round flat-cylindrical tablets from brown to dark brown or almost black in color with a bluish tinge with an uneven surface color, with a chamfer and a score.

Structure

Composition for one tablet

Active ingredient: silver proteinate (protargol) - 200.0 mg.

Excipient: hydroxypropyl methylcellulose - 10.0 mg.

Special conditions

It is possible to stain the discharge from the nose in gray or blue.

Read the instructions for use carefully before using the drug.

Please keep the instructions for future use.

If you have any questions, see your doctor.

The medicinal product with which you are being treated is intended for you personally, and it should not be passed on to others, since it may harm them further if you have the same symptoms as you.

The effect of the drug on the ability to drive vehicles, mechanisms

The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.

Drug interactions

Pharmacodynamic, pharmacokinetic interaction: not studied.

Pharmaceutical interaction: salts of zinc, copper, lead, silver, mercury, iron, aluminum form insoluble precipitates with a solution of silver proteinate

a solution of silver proteinate is inactivated by alkaloid salts and organic bases (epinephrine).

If you are using the above or other drugs (including over-the-counter), consult your doctor before using Protargol - ENT.

Pharmacodynamics

When ingested, silver proteinate dissociates to form silver ions, which have an astringent, antiseptic and anti-inflammatory effect.

Silver ions actively inhibit the reproduction of infectious agents by binding their DNA.

The mechanism of action is based on the fact that silver ions on the damaged mucous membrane precipitate proteins and form a protective film.

At the same time, sensitivity decreases, blood vessels narrow (this leads to a decrease in edema) and the inflammatory process is suppressed.

Silver ions also inhibit the growth of various bacteria.

It is active against gram-positive and gram-negative bacteria: V. segesh, C. albicans, E. coli, P. aeruginosa.

C. aureus, A. niger, S. abony, etc.

Pharmokinetics

When applied topically, it is practically not absorbed.

Indications

Symptomatic therapy for acute nasopharyngitis (rhinitis), sinusitis.

Contraindications

Hypersensitivity to the components of the drug, atrophic rhinitis, pregnancy, breastfeeding, children under 3 years of age (for a given dosage).

Application during pregnancy and during breastfeeding

The use of the drug during pregnancy and during breastfeeding is contraindicated.

Overdose

Symptoms: with the recommended route of administration, overdose is unlikely.

Possible increased side effects.

If a large amount of the drug is accidentally swallowed, irritation of the gastrointestinal tract may occur.

With prolonged uncontrolled use of the drug, it is theoretically possible that a very rare disease - argyrosis (staining in a gray or bluish color of the skin and mucous membranes) appears.

Subject to the recommended dosing regimen, the risk of argyrosis is unlikely.

Treatment.

In case of severe irritation, burning, itching of eyes, skin, mucous membranes, rinse with plenty of water for 15 minutes.

Treatment is symptomatic.

Side effects

-Allergic reactions: itching, mucosal irritation, urticaria

- a burning sensation and numbness

- dry mouth

- redness of the eyes

-anaphylactic shock

- Quincke's library

-atopic dermatitis.

If any of the side effects indicated in the instructions are aggravated, the drug should be canceled.

If any of the side effects indicated in the instructions are aggravated by shea you notice any other side effects that are not listed in the instructions, inform your doctor.

Special storage conditions

Store the prepared solution for no more than 30 days in a dark place at a temperature not exceeding 25 ° C.

Dosage

200mg

Indications

Symptomatic therapy for acute nasopharyngitis (rhinitis), sinusitis.

Storage conditions and periods

At a temperature not exceeding 25 degrees, in the original packaging.

Expiration date: 2 years

after preparation - 30 days (in a dark place, at a temperature not exceeding 25 degrees)

INN / Active ingredient

Silver proteinate

Contraindications

Hypersensitivity to the drug, atrophic rhinitis, pregnancy, breastfeeding, children under 3 years of age (for a given dosage).

Specifications

Category

Runny nose

Scope of the drug

Ear, Throat, Nose

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

one

Vacation conditions

Without recipe

Brand name

Pharmstandard

Components

pipette cap, bottle

The amount of the dosage form in the primary package

1 PC.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiseptic

Anatomical and therapeutic characteristics

R01AX10 Other preparations

Dosage form

Tablets for preparation of a solution for topical use

Dosage (volume) of the substance in the preparation

silver proteinate (protargol) - 200.0 mg.

Expiration date in days

730

Package weight, g

twenty