Protargol 0.2 N1 bottle, portions for solution for topical application + solution

Dosage form

Light amorphous powder from yellow-brown to brown, odorless.

Slightly hygroscopic.

The appearance changes under the influence of light.

Structure

Active substance:

Silver proteinate (protargol) - 200.0 mg

Solvent: water for injection - 10.0 ml

general description

Antiseptic

Special conditions

Application during pregnancy and during breastfeeding

The use of the drug during pregnancy is contraindicated.

The drug is not recommended for use by nursing mothers

if necessary, use of the drug, breastfeeding should be discontinued.

It is possible to stain the discharge from the nose in gray or blue.

Influence on the ability to drive vehicles, mechanisms

Does not affect.

Drug interactions

Pharmacodynamic, pharmacokinetic interaction: not studied.

Pharmaceutical interaction: salts of zinc, copper, lead, silver, mercury, iron, aluminum form insoluble precipitates with a solution of silver proteinate

a solution of silver proteinate is inactivated by alkaloid salts and organic bases (epinephrine).

If you are using the above or other drugs (including over-the-counter) when using Protargol, consult your doctor.

Pharmacodynamics

Silver preparation.

Has astringent, antiseptic and anti-inflammatory effects.

Dissociates with the formation of silver ions, which bind to the DNA of bacteria and prevent their reproduction on the mucous membranes under conditions of local application.

Pharmokinetics

When applied topically, it is practically not absorbed.

Indications

Symptomatic therapy for acute nasopharyngitis (rhinitis), sinusitis.

Contraindications

Hypersensitivity to the drug, atrophic rhinitis, pregnancy, breastfeeding, children under 3 years of age (for a given dosage).

Overdose

Symptoms

With the recommended route of administration, overdose is unlikely.

Possible increased side effects.

If a large amount of the drug is accidentally swallowed, irritation of the gastrointestinal tract may occur.

With prolonged uncontrolled use of the drug, it is theoretically possible the appearance of a very rare disease - argyrosis (staining in a gray or bluish color of the skin and mucous membranes).

Subject to the recommended dosing regimen, the risk of argyrosis is unlikely.

Treatment.

In case of severe irritation, burning, itching of eyes, skin, mucous membranes, rinse with plenty of water for 15 minutes.

Treatment is symptomatic.

Side effects

Slight irritation of the mucous membrane, burning, itching, allergic reactions (urticaria, atopic dermatitis, Quincke's edema, anaphylactic shock).

If you have any side effects indicated in the instructions, or they are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor.

Special storage conditions

Store the reconstituted solution in a dark place at a temperature of 2 to 8 ° C for -14 days.

Dosage

200mg x 200mg

Indications

Symptomatic therapy for acute nasopharyngitis (rhinitis), sinusitis.

Contraindications

Hypersensitivity to the drug, atrophic rhinitis, pregnancy, breastfeeding, children under 3 years of age (for a given dosage).

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 2.5 years

reconstituted solution - 14 days (in a dark place, at a temperature of 2 to 8 degrees)

INN / Active ingredient

Silver proteinate

Specifications

Category

Runny nose

Scope of the drug

Ear, Throat, Nose

Release form

Solution

Manufacturer country

Russia

Package quantity, pcs

one

Vacation conditions

Without recipe

Components

pipette cap, solvent (ampoules) 10 ml

The amount of the dosage form in the primary package

200 mg

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiseptic

Anatomical and therapeutic characteristics

R01AX10 Other preparations

Dosage form

Powder for solution for topical application

Expiration date in days

912

Package weight, g

60