Prazicide suspension Plus for puppies of small breeds 6ml

DESCRIPTION

Prazicide-suspension Plus for puppies and small breeds is an anthelmintic preparation in the form of a suspension.

In appearance, the drug is a suspension of light yellow color; during storage, stratification of the suspension is allowed, which disappears when shaken.

ADVANTAGES

Allows you to get rid of helminths (worms) most gently and effectively.

A wide range of anthelmintic action.

The drug is easily dosed to the weight of any animal.

The pleasant taste and aroma of milk chocolate suit even the most capricious animals.

The set includes: a convenient syringe dispenser.

Veterinary passport stickers.

COMPOSITION

In 1 ml Prazicide-suspension Plus for adult dogs, puppies of medium and large breeds contains: 45 mg of pyrantel pamoate, 45 mg of febantel, 15 mg of praziquantel and auxiliary substances: polyvinylpyrrolidone - 32 mg, glycerin - 50 mg, aspasvit C-200 - 5 mg, tween-80 - 6 mg, xanthan gum - 2.5 mg, sodium benzoate - 1.5 mg, potassium sorbate - 1.5 mg, antifoam - 0.7 mg, citric acid - 0.5 mg, flavor ' Milk chocolate '- 1 mg, Na-carboxymethyl cellulose - 2.5 mg and purified water - up to 1 ml; Prazicide-suspension Plus for adult cats, kittens and puppies of small breeds contains: 15 mg of pyrantel pamoate, 15 mg of febantel, 1.5 mg of praziquantel and auxiliary substances: polyvinylpyrrolidone - 10 mg, glycerin - 50 mg, aspasvit C-200 - 5 mg , tween-80 - 6 mg, xanthan gum - 3 mg, sodium benzoate - 1.5 mg, potassium sorbate - 1.5 mg, antifoam - 0.7 mg,

PHARMACOLOGICAL PROPERTIES

Prazicide-suspension Plus refers to combined anthelmintic drugs. The combination of praziquantel, febantel and pyrantel pamoate, which are part of the preparation, provides a wide spectrum of its anthelmintic action on gastrointestinal nematodes (Toxosara canis, Toxocara cati, Toxosara mistax, Toxascaris leonina, Uncinaria stenocephala, Trichlosturis vulpistodes) granulosus, Alveococus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobotrium latum, Multiceps multiceps), parasitizing dogs and cats.

Pirantel pamoat is a compound of the pyrimidine group, its mechanism of action is based on blocking the transmission of nerve impulses in neuromuscular synapses by depolarizing the membranes of muscle cells, which causes paralysis of the muscular system of nematodes; pyrantel is poorly absorbed, which ensures its prolonged action on helminths in the intestine; excreted from the body mostly unchanged (93%) with feces.

Praziquantel is a compound of the pyrazinisoquinoline group that is active against gastrointestinal cestodes at all stages of development. By increasing the permeability of the parasite's cell membranes for calcium ions (Ca2 +), it causes membrane depolarization, muscle contraction and destruction of the tegument, which leads to the death of helminths and promotes their excretion from the animal's body. The compound is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in the blood plasma after 1-3 hours, reversibly binds to serum proteins (70-80%), partially metabolized in the liver, re-excreted into the intestine, excreted from the body mainly in the urine (up to 80%) within 24 hours. Febantel refers to probenzimidazoles, which are biotransformed in the body into benzimidazoles.

The mechanism of action of febantel is based on inhibition of the enzyme fumarate reductase in the mitochondria of helminths, as a result of which glucose uptake and protein synthesis of tubulin are disrupted, which leads to the destruction of the microtubular apparatus of the parasite cells, causing its death. Febantel is absorbed in the intestines, metabolized in the liver and excreted with bile into the intestinal lumen, where its re-resorption is partially noted; it is excreted from the body both in unchanged form and in the form of several metabolites with feces and urine.

Prazicide-suspension Plus in terms of the degree of impact on the body refers to substances of low hazard (hazard class 4 according to GOST 12.1.007-76), in recommended doses it does not have an embryotoxic, teratogenic and sensitizing effect, is well tolerated by dogs and cats of different breeds and ages.

INDICATIONS

Prazicide-suspension Plus is prescribed to puppies from 3 weeks of age with prophylactic and therapeutic purposes for gastrointestinal nematoses (toxocariasis, toxascariasis, uncinariosis, trichocephalosis, ankylostomiasis), cestodoses (teniidosis, dipyldiosis, echinococcidosis) invasions.

APPLICATION

The drug is administered to animals orally individually, in the morning feeding with a small amount of food, or is injected forcibly onto the root of the tongue using a syringe-dispenser in the following doses: 1 ml per 1 kg of animal weight. For preventive purposes, deworming of animals is carried out once a quarter, as well as before each vaccination. For therapeutic purposes, as well as for the purpose of prophylaxis in case of group (crowded) keeping of animals (nurseries, shelters, vivariums), the treatment is carried out twice with an interval of 14 days: with nematodes once a day, with cestodes and mixed nematodes-cestodes once a day day for 3 consecutive days.

A preliminary fasting diet and the use of laxatives before deworming are not required. The suspension bottle should be shaken thoroughly before each use.

Violations of the deworming scheme should be avoided, as this can lead to a decrease in effectiveness. If the next dose is missed, the drug must be administered as soon as possible in the same dose, then the interval between drug injections does not change.

OVERDOSE

In case of an overdose of the drug, the animal may experience a depression, refusal to feed, excessive salivation, and upset of the gastrointestinal tract. In these cases, enterosorbents and symptomatic therapy are used.

SIDE EFFECTS

When using Prazicide-suspension Plus in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. In some animals, disturbances in the functioning of the gastrointestinal tract (loose stools, vomiting) and increased salivation are possible, which disappear spontaneously and do not require the use of drugs. With increased individual sensitivity to the components of the drug and the appearance of allergic reactions, its use is discontinued and antihistamines and symptomatic therapy are prescribed to the animal.

CONTRAINDICATIONS

A contraindication to use is an individual intolerance to the components of the drug (including a history). Prazicide-suspension Plus should not be used in females in the first half of pregnancy, in puppies and kittens under 3 weeks of age, malnourished, sick with infectious diseases and convalescent animals. Deworming of pregnant and lactating females, if necessary, is carried out under the supervision of a veterinarian 3 weeks before the expected birth and 2-3 weeks after birth.

Do not use Prazicide-Suspension Plus simultaneously with medicinal preparations containing piperazine and cholinesterase inhibitors. There are no data on the incompatibility of Prazcid-suspension Plus with drugs of other pharmacological groups and feed additives.

Prazicide suspension Plus is not intended for use in productive animals.

STORAGE

Store the drug in the manufacturer's sealed packaging, in a dry, dark place, separate from food and feed, at a temperature from 0 В° C to 25 В° C. The shelf life of the drug, subject to storage conditions, is 2 years from the date of production. It is prohibited to use Prazicide-suspension Plus after the expiration date.

PACKING

The drug is packaged in 6 ml polymer bottles.

Specifications

KolVUP

ten

Manufacturer

APICENNA

Temperature regime

from 0 to +25

Teaser

for deworming small breed puppies with nematodes and cystoses