Prazicide suspension Plus for dogs 10ml

DESCRIPTION

Prazicide-suspension Plus drug for deworming adult dogs with nematodes and cestodes.

INDICATIONS

Prazicide-suspension Plus is prescribed for preventive and therapeutic deworming of adult dogs against nematodes and cestodes, including mixed infestations.

COMPOSITION

In 1 ml of prazicide suspension Plus, praziquantel - 15 mg / ml and pyrantel pamoat - 45 mg / ml, febantel - 45 mg / ml, excipients as active ingredients.

PHARMACOLOGICAL PROPERTIES

Sweet prazicide suspension is a combined preparation with a wide spectrum of activity against all stages of the development of round and tape helminths, including Toxocara canis, Toxascaris leonina, Uncinaria spp., Ancylostoma spp., Trichuris vulpis, Echinococcus Mesocesto granulosatcus, Echinoiscocides , Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp., Parasitizing in dogs. Praziquantel, which is part of the suspension, increases the permeability of cell membranes for calcium ions and inhibits the parasite's enzyme - fumarate reductase, causing spastic contraction of the muscles, turning into paralysis. The mechanism of action of pyrantel pamoate is to block neuromuscular transmission, impair the permeability of cell membranes and inhibition of cholinesterase, which leads to paralysis and death of the helminth. When administered orally, praziquantel is rapidly absorbed in the gastrointestinal tract, reaches its maximum concentration in the blood plasma after 1 to 3 hours, is distributed in the organs and tissues of the animal, and is excreted from the body as metabolites in the urine (up to 80%) within 24 hours. Pirantel pamoate is poorly absorbed in the gastrointestinal tract, providing a longer parasiticidal effect directly in the intestine, and is excreted from the body mainly unchanged with feces (93%). The drug is easy to use, tastes good and is fairly well eaten by dogs. In terms of the degree of effect on the body of warm-blooded animals, Prazicide-suspension sweet refers to moderately hazardous substances and in recommended doses does not have a local irritating, sensitizing, teratogenic and embryotoxic effect.

APPLICATION AND DOSAGE

Sweet prazicide suspension is administered to the animals once individually in the morning feeding with a small amount of food or injected directly onto the root of the tongue using a syringe dispenser at the rate of 1 ml of suspension per 3 kg of body weight. Before use, the suspension bottle must be shaken thoroughly for 1? 2 minutes. A preliminary fasting diet and the use of laxatives are not required when using the drug. For prophylactic purposes, deworming is carried out every 3 months, as well as before each vaccination. Therapeutic measures against nematodes and cestodes are carried out according to indications. With a strong degree of invasion, the suspension is re-set after 10 days. For pregnant females, the drug is prescribed 3 weeks before the expected birth with caution, under the supervision of a veterinarian, for lactating females - 2 - 3 weeks after birth.

CONTRAINDICATIONS

Increased individual sensitivity to drug components. It is not recommended to deworm females in the first half of pregnancy and within 3 weeks after childbirth, as well as patients with infectious diseases, convalescent and malnourished animals. Do not administer the suspension simultaneously with piperazine derivatives and other drugs that inhibit cholinesterase.

STORAGE

Store the drug in a closed manufacturer's packaging in a dry, dark place, separate from food and feed, at a temperature of 0 В° C to 25 В° C.

SHELF LIFE

The shelf life of the drug, subject to storage conditions, is 2 years from the date of production.

Specifications

KolVUP

ten

Manufacturer

APICENNA

Temperature regime

from 0 to +25

Teaser

for deworming adult dogs with nematodes and cestodes