Pratel 10 tablets
DESCRIPTION
Pratel is a combined anthelmintic drug. It is a pill of light yellow color, round in shape with beveled edges and a cruciform notch on one side.
COMPOSITION
1 tablet contains 144 mg of pyrantel embonate and 50 mg of praziquantel.
PHARMACOLOGICAL PROPERTIES
Combined anthelmintic drug. It has a wide spectrum of nematicidal and cestocidal action on all phases of development of round and tapeworms parasitizing in dogs and cats, incl. Toxocara canis, Toxocara cati, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Ancylostoma tubaeforme, Hydatigera taeniaeformis, Dipylidium caninum, Echinococcus granulosis, Echinococcus multilocularis.
The mechanism of action of the active components included in the drug is based on inhibition of fumarate reductase, persistent depolarization of muscle cells of the helminth, disruption of energy metabolism, which causes paralysis and death of the parasite, promotes its excretion from the gastrointestinal tract.
Praziquantel acts on tapeworms (cestodes). Primarily, it causes muscular excitement, leading to spastic paralysis of the muscles of the parasite. This leads to the vacuolization of the helminth cell membranes, which allows intestinal enzymes to act on the parasite, causing its death. When administered orally, praziquantel is rapidly absorbed in the intestine and distributed in organs and tissues, excreted from the body mainly in the urine in a metabolized form.
Pirantel is active against gastrointestinal nematodes. It is a neuromuscular ganglion blocker that causes persistent depolarization and spastic paralysis of the musculature of the roundworms. Pirantela embonate is partially absorbed in the intestine and excreted from the body mainly with feces within 24-48 hours. In terms of the degree of effect on the body, Pratel is classified as a low-hazard substance (hazard class 4 according to GOST 12.1.007-76) in recommended doses does not have a sensitizing effect, embryotoxic and teratogenic action. Well tolerated by dogs and cats of different breeds and ages.
INDICATIONS
Treatment and prevention of helminthiasis in dogs and cats, including: nematodes (toxocariasis, toxascariasis, uncinariosis, hookworm disease); cestodoses (teniasis, dipylidiosis, echinococcosis, mesocestodosis).
APPLICATION
The tablets are administered to dogs and cats once, individually in crushed form with food or forcibly on the root of the tongue in the following doses:
Type of animal, kg Number of tablets
kittens and dogs weighing up to 2kg ? pills
cats and dogs weighing from 2 to 5 kg ? pills
dogs weighing from 5 to 10kg 1 tablet
dogs weighing from 10 to 20kg 2 tablets
dogs weighing from 20 to 30 kg 3 tablets
dogs weighing from 30 to 40 kg 4 tablets
dogs weighing from 40 to 50kg 5 tablets
Pratel can be used in puppies and kittens from 6 weeks of age. A preliminary fasting diet and the use of laxatives before deworming are not required.
For therapeutic purposes, the drug is administered to animals once, for prophylactic purposes - once a quarter, as well as before vaccination and 2-4 weeks before the expected mating time in a therapeutic dose.
For pregnant females, the drug is used in the last third of pregnancy, for lactating females - 2-3 weeks after birth under the supervision of a veterinarian. The peculiarities of the action of the drug during its first use and cancellation have not been established.
If the next preventive deworming is missed, it should be carried out as soon as possible in the same dose.
SIDE EFFECTS
When using the drug according to indications and in recommended doses, side effects and complications are usually not observed.
With increased individual sensitivity of the animal to the components of the drug, allergic reactions are possible. Overdose symptoms have not been identified in dogs and cats.
CONTRAINDICATIONS
Increased individual sensitivity to the components of the drug, incl. in the anamnesis. It is forbidden to use Pratel in the first half of pregnancy, severely malnourished, sick with infectious diseases and recovering animals. It is not allowed to use the drug in case of severe violations of the liver and kidneys, as well as in puppies and kittens younger than 6 weeks of age. Do not exceed or underestimate the recommended doses of Pratel.
SPECIAL INSTRUCTIONS
With increased individual sensitivity of the animal to the components of the drug and the development of allergic reactions, its use is stopped and desensitizing therapy is carried out.
Pratel should not be used simultaneously with anthelmintic drugs containing piperazine.
The terms of use of livestock products after the use of the drug Pratel are not regulated.
PRECAUTIONS
When working with Pratel, you should follow the general rules of personal hygiene and safety measures provided for when working with medicines. When working with the drug, it is prohibited to drink, smoke and eat. After handling the preparation, wash your hands thoroughly with soap and water.
No special precautions are required when disposing of unused medicinal product.
STORAGE
Store in closed manufacturer's packaging, separate from food and feed, in a dry, dark place and out of reach of children and animals at temperatures from 0 В° C to 25 В° C. The shelf life is 3 years.
PACKING
Packed in 10 tablets in blisters, which are put in 1 or 10 blisters in cardboard boxes.
Specifications
KolVUP
ten
Manufacturer
Novartis Lek
Temperature regime
from 0 to +25
Teaser
broad spectrum anthelmintic for dogs and cats